Patents by Inventor Thomas Neils
Thomas Neils has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20130118609Abstract: The invention described herein pertains to an improved method of controlling the flow of gases into a process chamber. The method incorporates a gas source, one or more pressure reduction stages, a throttle valve, a pressure gauge, and a control system. When connected to a process chamber held at sub-atmospheric pressure, the invention provides a steady flow of gas such that the stability of said flow is superior to many commercially available metering devices, such as thermally-based mass flow controllers.Type: ApplicationFiled: October 25, 2012Publication date: May 16, 2013Inventor: Thomas Neil Horsky
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Patent number: 8377930Abstract: Compounds that inhibit PDE10 are disclosed that have utility in the treatment of a variety of conditions, including (but not limited to) psychotic, anxiety, movement disorders and/or neurological disorders such as Parkinson's disease, Huntington's disease, Alzheimer's disease, encephalitis, phobias, epilepsy, aphasia, Bell's palsy, cerebral palsy, sleep disorders, pain, Tourette's syndrome, schizophrenia, delusional disorders, drug-induced psychosis and panic and obsessive-compulsive disorders. Pharmaceutically acceptable salts, stereoisomers, solvates and prodrugs of the compounds are also provided. Also disclosed are compositions containing a compound in combination with a pharmaceutically acceptable carrier, as well as methods relating to the use thereof for inhibiting PDE10 in a warm-blooded animal in need of the same.Type: GrantFiled: August 4, 2009Date of Patent: February 19, 2013Assignee: Omeros CorporationInventors: Neil S. Cutshall, Jennifer Lynn Gage, Thomas Neil Wheeler
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Patent number: 8343970Abstract: Compounds that inhibit PDE10 are disclosed that have utility in the treatment of a variety of conditions, including (but not limited to) psychotic, anxiety, movement disorders and/or neurological disorders such as Parkinson's disease, Huntington's disease, Alzheimer's disease, encephalitis, phobias, epilepsy, aphasia, Bell's palsy, cerebral palsy, sleep disorders, pain, Tourette's syndrome, schizophrenia, delusional disorders, drug-induced psychosis and panic and obsessive-compulsive disorders. Pharmaceutically acceptable salts, stereoisomers, solvates and prodrugs of the compounds are also provided. Also disclosed are compositions containing a compound in combination with a pharmaceutically acceptable carrier, as well as methods relating to the use thereof for inhibiting PDE10 in a warm-blooded animal in need of the same.Type: GrantFiled: March 10, 2011Date of Patent: January 1, 2013Assignee: Omeros CorporationInventors: Neil S. Cutshall, Jennifer Lynn Gage, Thomas Neil Wheeler, Thomas L. Little
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Publication number: 20120214144Abstract: A patient simulator system for teaching patient care is provided. The system includes a patient simulator. The patient simulator includes a patient body comprising one or more simulated body portions. The one or more simulated body portions include a lung compliance simulation system in some instances. In that regard, the lung compliance system is configured to be used with an external ventilator, including positive end-expiratory pressure (PEEP) and assisted-control ventilation. In some instances, the lung compliance system includes a lung compartment, a simulated lung positioned within the lung compartment, where the lung compartment defines an available volume for the simulated lung to expand into and where the available volume for the simulated lung to expand into is adjustable to control a compliance of the simulated lung.Type: ApplicationFiled: February 18, 2011Publication date: August 23, 2012Applicant: GAUMARD SCIENTIFIC COMPANY, INC.Inventors: Thomas Neil Trotta, Siobhain Lowe, Alberto Rodriguez, Miguel Enrique Carvajal, Victor I. Fernandez
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Patent number: 8202299Abstract: Devices, tools and methods for minimally invasive implantation of a dynamic interspinous implant device for distracting between spinous processes and providing dynamic stabilization. One exemplary device includes a main body including a shaft having a longitudinal axis; a first clamping mechanism having first and second jaws configured to clamp a spinous process of a first vertebra, and a second clamping mechanism having third and fourth jaws configured to clamp a spinous process of a second vertebra. The first, second, third and fourth jaws extend transversely from the shaft and at least two of two of the jaws are releasably mounted to the shaft and are mountable to and removable from the shaft by relative movement between the respective jaw and the shaft in a direction normal to a longitudinal axis of the shaft.Type: GrantFiled: March 19, 2008Date of Patent: June 19, 2012Assignee: Collabcom II, LLCInventors: Jeffrey Chun Wang, Thomas Neil Scioscia, Adrian Slattery, Alan W. Cannon
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Publication number: 20120101863Abstract: A method is disclosed for using information related to the service history of a power-train component. The method may include using a machine-management system with at least one information processor to acquire information related to loads experienced by the power-train component during a first period, the first period occurring before a disassembly procedure involving disassembly of the power-train component from a power train. The method may also include employing the machine-management system and the acquired information related to loads experienced by the power-train component during the first period to perform one or more tasks in connection with use of the power-train component after the disassembly procedure.Type: ApplicationFiled: October 22, 2010Publication date: April 26, 2012Inventors: Byron Edwin Truax, Rick Thomas Lasko, Jason Edward Carter, Conrad Gene Grembowicz, Thomas Neil Brooks, JR., Christopher John Beckman, Christopher Michael Sprock, Lonny Eric Johnson
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Patent number: 8154210Abstract: An ion source is disclosed incorporating various aspects of the invention including i) a vaporizer, ii) a vaporizer valve, iii) a gas feed, iv) an ionization chamber, v) an electron gun, vi) a cooled mounting frame, and vii) an ion exit aperture. The ion source includes means for introducing gaseous feed material into the ionization chamber, means for vaporizing solid feed materials and introducing their vapors into the ionization chamber, means for ionizing the introduced gaseous feed materials within the ionization chamber, and means for extracting the ions thus produced from an ion exit aperture adjacent to the ionization region. In addition, means for accelerating and focusing the exiting ions are provided. The vaporizer, vaporizer valve, gas feed, ionization chamber, electron gun, cooled mounting frame, and ion exit aperture are all integrated into a single assembly in preferred embodiments of the novel ion source.Type: GrantFiled: December 18, 2009Date of Patent: April 10, 2012Assignee: SemEquip, Inc.Inventors: Thomas Neil Horsky, John Noel Williams
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Publication number: 20110224202Abstract: Compounds that inhibit PDE10 are disclosed that have utility in the treatment of a variety of conditions, including (but not limited to) psychotic, anxiety, movement disorders and/or neurological disorders such as Parkinson's disease, Huntington's disease, Alzheimer's disease, encephalitis, phobias, epilepsy, aphasia, Bell's palsy, cerebral palsy, sleep disorders, pain, Tourette's syndrome, schizophrenia, delusional disorders, drug-induced psychosis and panic and obsessive-compulsive disorders. Pharmaceutically acceptable salts, stereoisomers, solvates and prodrugs of the compounds are also provided. Also disclosed are compositions containing a compound in combination with a pharmaceutically acceptable carrier, as well as methods relating to the use thereof for inhibiting PDE10 in a warm-blooded animal in need of the same.Type: ApplicationFiled: March 10, 2011Publication date: September 15, 2011Applicant: Omeros CorporationInventors: Neil S. Cutshall, Jennifer Lynn Gage, Thomas Neil Wheeler, Thomas L. Little
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Publication number: 20110207103Abstract: Devices, systems, and methods appropriate for use in medical training that include materials that better mimic natural human tissue are disclosed. In one aspect a polysiloxane mixture for simulating human biological tissue, especially human breast tissue, is disclosed. In another aspect, a method of manufacturing a biological tissue ultrasound phantom is disclosed. In another aspect, a human breast tissue models are disclosed. In some instances, the human breast tissue model includes at least one simulated pathological structure that simulates such pathologies as a cyst, a medullary carcinoma, a ductal carcinoma, an infiltrating scirrhus carcinoma, a lobular carcinoma, and a fibroadenoma.Type: ApplicationFiled: February 18, 2011Publication date: August 25, 2011Applicant: GAUMARD SCIENTIFIC COMPANY, INC.Inventors: Thomas Neil Trotta, Jennifer Anne Trotta, Siobhain Lowe
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Publication number: 20110207102Abstract: A patient simulator system for teaching patient care is provided. The system includes a patient simulator. The patient simulator includes a patient body comprising one or more simulated body portions. The one or more simulated body portions include at least one simulated finger that is configured to interface with a pulse oximeter to simulate an oxygen saturation of the patient simulator. In some instances, the simulated finger is further configured to interface with the pulse oximeter to simulate a pulse rate of the patient simulator. In some embodiments, the simulated finger may be calibrated to accurately interface with a particular pulse oximeter. Methods of utilizing the patient simulator systems, including the simulated finger for interfacing with a pulse oximeter, are also provided.Type: ApplicationFiled: February 19, 2010Publication date: August 25, 2011Applicant: GAUMARD SCIENTIFIC COMPANY, INC.Inventors: Thomas Neil Trotta, Siobhain Lowe, Alberto Rodriguez, Miguel Enrique Carvajal, Victor I. Fernandez
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Publication number: 20110207104Abstract: Devices, systems, and methods appropriate for use in medical training that include materials that better mimic natural human tissue are disclosed. In one aspect a polysiloxane mixture for simulating human biological tissue, especially human breast tissue, is disclosed. In another aspect, a method of manufacturing a biological tissue phantom is disclosed. In another aspect, a human breast tissue models are disclosed. In one instances, the human breast tissue model comprises a simulated breast tissue comprising a mixture of a silicone foam and a silicone oil and a simulated skin layer covering the simulated breast tissue, where the simulated breast tissue and the simulated skin layer are sized and shaped to mimic a natural human breast. In some instances, the human breast tissue model includes at least one simulated pathological structure that simulates such pathologies as a cyst, a medullary carcinoma, a ductal carcinoma, an infiltrating scirrhus carcinoma, a lobular carcinoma, and a fibroadenoma.Type: ApplicationFiled: February 18, 2011Publication date: August 25, 2011Applicant: Gaumard Scientific Company, Inc.Inventors: Thomas Neil Trotta, Jennifer Anne Trotta, Siobhain Lowe
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Patent number: 7994031Abstract: A method of manufacturing a semiconductor device is further described, comprising the steps of providing a supply of dopant atoms or molecules into an ionization chamber, combining the dopant atoms or molecules into clusters containing a plurality of dopant atoms, ionizing the dopant clusters into dopant cluster ions, extracting and accelerating the dopant cluster ions with an electric field, selecting the desired cluster ion by mass analysis, modifying the final implant energy of the cluster ion through post-analysis ion optics, and implanting the dopant cluster ions into a semiconductor substrate. In general, dopant clusters contain n dopant atoms where n can be 2, 3, 4 or any integer number. This method provides the advantages of increasing the dopant dose rate to n times the implantation current with an equivalent per dopant atom energy of 1/n times the cluster implantation energy.Type: GrantFiled: December 29, 2006Date of Patent: August 9, 2011Assignee: Semequip, Inc.Inventors: Thomas Neil Horsky, Dale Conrad Jacobson, Wade Allen Krull
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Patent number: 7800312Abstract: A direct electron impact ion source is disclosed that includes a vaporizer for producing a process gas; an electron source for generating an electron beam; and an ionization chamber. The electron source is located outside the ionization chamber. Aligned apertures are provided in opposing walls of the ionization chamber to allow an electron beam to pass through the ionization chamber. The process gas is directed into the ionization chamber and ionized and extracted from the ionization chamber by way of an extraction aperture. In one embodiment, the direct electron impact ion source is configured with a form factor to enable it to be retrofit into the volume of an existing ion source , for example, an arc discharge type ion source. Alternatively, the direct electron impact ion source may be used together with an arc discharge ion source to create a dual mode or universal ion source.Type: GrantFiled: September 26, 2006Date of Patent: September 21, 2010Assignee: SemEquip, Inc.Inventor: Thomas Neil Horsky
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Publication number: 20100148089Abstract: An ion source is disclosed incorporating various aspects of the invention including i) a vaporizer, ii) a vaporizer valve, iii) a gas feed, iv) an ionization chamber, v) an electron gun, vi) a cooled mounting frame, and vii) an ion exit aperture. The ion source includes means for introducing gaseous feed material into the ionization chamber, means for vaporizing solid feed materials and introducing their vapors into the ionization chamber, means for ionizing the introduced gaseous feed materials within the ionization chamber, and means for extracting the ions thus produced from an ion exit aperture adjacent to the ionization region. In addition, means for accelerating and focusing the exiting ions are provided. The vaporizer, vaporizer valve, gas feed, ionization chamber, electron gun, cooled mounting frame, and ion exit aperture are all integrated into a single assembly in preferred embodiments of the novel ion source.Type: ApplicationFiled: December 18, 2009Publication date: June 17, 2010Inventors: Thomas Neil Horsky, John Noel Williams
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Patent number: 7732787Abstract: An ion source is disclosed that is capable of providing ions of decaborane in commercial ion current levels to the ion extraction system of an ion implanter is provided, the ion source comprising an ionization chamber defined by walls enclosing an ionization volume, there being an ion extraction aperture in a side wall of the ionization chamber, arranged to enable the ion current to be extracted from the ionization volume by an extraction system, an electron gun mounted on a support that is outside of and thermally isolated from the walls of the ionization chamber, the ion extraction aperture plate is biased to a negative voltage with respect to the ionization chamber to further increase the drift velocity of the ions, and hence the maximum obtainable current in the resulting ion beam.Type: GrantFiled: December 29, 2006Date of Patent: June 8, 2010Assignee: Semequip, Inc.Inventor: Thomas Neil Horsky
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Publication number: 20100035872Abstract: Compounds that inhibit PDE10 are disclosed that have utility in the treatment of a variety of conditions, including (but not limited to) psychotic, anxiety, movement disorders and/or neurological disorders such as Parkinson's disease, Huntington's disease, Alzheimer's disease, encephalitis, phobias, epilepsy, aphasia, Bell's palsy, cerebral palsy, sleep disorders, pain, Tourette's syndrome, schizophrenia, delusional disorders, drug-induced psychosis and panic and obsessive-compulsive disorders. Pharmaceutically acceptable salts, stereoisomers, solvates and prodrugs of the compounds are also provided. Also disclosed are compositions containing a compound in combination with a pharmaceutically acceptable carrier, as well as methods relating to the use thereof for inhibiting PDE10 in a warm-blooded animal in need of the same.Type: ApplicationFiled: August 4, 2009Publication date: February 11, 2010Applicant: Omeros CorporationInventors: Neil S. Cutshall, Jennifer Lynn Gage, Thomas Neil Wheeler
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Publication number: 20090240280Abstract: Devices, tools and methods for minimally invasive implantation of a dynamic interspinous implant device for distracting between spinous processes and providing dynamic stabilization. One exemplary device includes a main body including a shaft having a longitudinal axis; a first clamping mechanism having first and second jaws configured to clamp a spinous process of a first vertebra, and a second clamping mechanism having third and fourth jaws configured to clamp a spinous process of a second vertebra. The first, second, third and fourth jaws extend transversely from the shaft and at least two of two of the jaws are releasably mounted to the shaft and are mountable to and removable from the shaft by relative movement between the respective jaw and the shaft in a direction normal to a longitudinal axis of the shaft.Type: ApplicationFiled: March 19, 2008Publication date: September 24, 2009Inventors: Jeffrey Chun Wang, Thomas Neil Scioscia, Adrian Slattery, Alan W. Cannon
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Publication number: 20090062918Abstract: Devices, tools and methods for minimally invasive implantation and distraction between spinous processes for treatment of spinous disorders. An interspinous implant device for distracting at least one pair of adjacent spinous processes includes a main body including a shaft having a longitudinal axis; and first and second arms extending transversely from the main body, wherein at least one of the first and second arms is slidably mounted with respect to the shaft. The arms are configured and dimensioned to extend laterally from both sides of the spinous processes when implanted therebetween and to be inserted between the spinous processes laterally from a single side thereof. The arms are variably positionable between a closed configuration, to facilitate insertion of the arms between the adjacent spinous processes, and an open configuration, in which the arms are separated from one another.Type: ApplicationFiled: August 30, 2007Publication date: March 5, 2009Inventors: Jeffrey Chun Wang, Thomas Neil Scioscia, Adrian Slattery, Alan W. Cannon
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Patent number: 7479643Abstract: The ionization chamber is defined by a removable block disposed in heat transfer relationship to a temperature controlled mounting block, preferably the removable block comprised of graphite, silicon carbide or aluminum. The ion source includes a mounting flange for joining the ion source to the housing of an ion implanter, the ionization chamber being located on the inside of the mounting flange and the vaporizer being removably mounted to the exterior of the mounting flange via at least one isolation valve which is separable from the mounting flange with the vaporizer, enabling the vaporizer charge volume to be isolated by the valve in closed position during handling, preferably there being two isolation valve in series, one unified with and transportable with a removed vaporizer unit, and one constructed to remain with and isolate the remainder of the ion source from the atmosphere.Type: GrantFiled: July 1, 2005Date of Patent: January 20, 2009Assignee: SemEquip, Inc.Inventor: Thomas Neil Horsky
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Publication number: 20080319389Abstract: The medical devices of the present invention include self-reinforcing polymer materials, based on the rigid-rod paraphenylene copolymer chemistry. Accordingly, the materials of the present invention provide a unique combination of physical properties that are advantageous for use in various medical devices. The medical devices may include those for maneuvering through the body passages of a patient, such as for example the circulatory system, to a desired site for treatment.Type: ApplicationFiled: September 28, 2005Publication date: December 25, 2008Inventors: Patricia A. Davis-Lemessy, Thomas Neil Trotta