Abstract: Presented are multilayer composite panels for motor vehicles, methods for making/using such panels, and motor vehicles with transparent composite roof panels having localized reinforcement features. A sandwich-type multilayer composite panel contains one or more exterior layers each including a transparent rigid material, one or more bonding layers each including a transparent adhesive material, and one or more structural reinforcement layers each including a fiber-reinforced polymer material. Each structural reinforcement layer may be attached directly to a bonding layer and/or exterior layer. The composite panel may also include one or more IR-reflective layers, one or more light-absorbing sunshade layers, and one or more insulating low-k layers.

Abstract: Compounds that are inhibitors of at least one of ARG1 and ARG2, and compositions containing the compounds and methods for synthesizing the compounds, are described herein. The use of such compounds and compositions for the treatment of a diverse array of diseases, disorders, and conditions, including cancer- and immune-related disorders that are mediated, at least in part, by ARG1 and ARG2 are also described herein.

Abstract: Compounds that are inhibitors of at least one of the ARG1 and ARG2, and compositions containing the compounds and methods for synthesizing the compounds, are described herein. The use of such compounds and compositions for the treatment of a diverse array of diseases, disorders, and conditions, including cancer- and immune-related disorders that are mediated, at least in part, by ARG1 and ARG2 are also described herein.

Abstract: A mold assembly device for use in sand casting of engine cylinder blocks is disclosed, the mold assembly device includes a magnet for securing a cast-in-place cylinder bore liner during assembly of a mold package, wherein the magnet militates against undesirable movement of the bore liner during assembly of the mold package.

Abstract: A mold assembly device for use in sand casting of engine cylinder blocks is disclosed, the mold assembly device includes a magnet for securing a cast-in-place cylinder bore liner during assembly of a mold package, wherein the magnet militates against undesirable movement of the bore liner during assembly of the mold package.

Abstract: A cast-in-place cylinder bore liner (15) is disclosed for use in sand casting of engine cylinder blocks, the cylinder bore liner (15) having a protuberant portion (60) adjacent a first end (61) thereof, whereby accuracy in the positioning of cast-in-place bore liners (15) is maximized.

Abstract: A method is disclosed for producing a casting mold for an engine block, the casting mold includes a mold seat for a cast-in-place cylinder bore liner, the seat having a surface disposed at an angle relative to a longitudinal axis of the cylinder bore liner, wherein the cylinder bore liner becomes slightly unseated upon thermal expansion.

Abstract: A mold design is disclosed for precision sand casting of engine cylinder blocks, such as engine cylinder V-blocks, having chills disposed therein, wherein an expansion and contraction caused by changes in temperature during the casting operation are accommodated by the chills.

Abstract: A mold design is disclosed for sand casting of engine cylinder blocks, such as engine cylinder V-blocks, with cast-in-place cylinder bore liners, wherein a dimensional accuracy in the positioning of cast-in-place bore liners is maximized.

Abstract: A casting mold for an engine block and method for manufacturing the casting mold. In one embodiment, the casting mold includes a mold seat with a double-curved surface, and a cast-in cylinder liner. The cylinder liner has an axis and an end surface. The end surface is in tangential contact with the double-curved surface in a seated position prior to any thermal expansion of the cylinder liner. In various embodiments, the cylinder liner becomes slightly unseated upon thermal expansion.