Patents by Inventor Thomas Newmark

Thomas Newmark has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8252345
    Abstract: The inventive subject matter relates to methods for modulating an eicosanoid metabolic process in cells of an animal in need thereof, which comprises administering to the animal an amount of the inventive compositions effective for regulating the activity of an eicosanoid oxygenase. In particular, the inventive subject matter relates to methods for modulating arachidonic acid metabolism by administering an amount of the inventive compositions effective for regulating the activity of lipoxygenases and cyclooxygenases.
    Type: Grant
    Filed: December 29, 2008
    Date of Patent: August 28, 2012
    Assignee: New Chapter Inc.
    Inventors: Thomas Newmark, Paul Schulick, Robert Newman, Bharat Aggarwal
  • Patent number: 8114446
    Abstract: The inventive subject matter relates to methods for modulating an eicosanoid metabolic process in cells of an animal in need thereof, which comprises administering to the animal an amount of the inventive compositions effective for regulating the activity of an eicosanoid oxygenase. In particular, the inventive subject matter relates to methods for modulating arachadonic acid metabolism by administering an amount of the inventive compositions effective for regulating the activity of lipoxygenases and cyclooxygenases.
    Type: Grant
    Filed: June 29, 2010
    Date of Patent: February 14, 2012
    Assignees: New Chapter Inc., Board Of Regents Of The University Of Texas System
    Inventors: Thomas Newmark, Paul Schulick, Robert Newman, Bharat Aggarwal
  • Publication number: 20110200689
    Abstract: The inventive subject matter relates to methods for treating glioblastoma, comprising administration of a composition comprising therapeutically effective amounts of supercritical extracts of rosemary, turmeric, oregano and ginger; and therapeutically effective amounts of hydroalcoholic extracts of holy basil, ginger, turmeric, Scutellaria baicalensis, rosemary, green tea, huzhang, Chinese goldthread, and barberry. The inventive subject matter further relates to methods for modulating gene expression of genes selected from the group consisting of interleukin-1?, interleukin-1?, heme oxygenase 1, aldo-keto reductase family 1, member C2, colony stimulating factor 3, leukemia inhibitory factor, heat shock 70 kDa protein, and combinations thereof, by administration of an effective amount of said compositions.
    Type: Application
    Filed: March 24, 2011
    Publication date: August 18, 2011
    Applicants: NEW CHAPTER INC., THE CLEVELAND CLINIC FOUNDATION
    Inventors: Thomas NEWMARK, Mladen GOLUBIC, Paul SCHULICK
  • Patent number: 7931922
    Abstract: The inventive subject matter relates to methods for treating glioblastoma, comprising administration of a composition comprising therapeutically effective amounts of supercritical extracts of rosemary, turmeric, oregano and ginger; and therapeutically effective amounts of hydroalcoholic extracts of holy basil, ginger, turmeric, Scutellaria baicalensis, rosemary, green tea, huzhang, Chinese goldthread, and barberry. The inventive subject matter further relates to methods for modulating gene expression of genes selected from the group consisting of interleukin-1?, interleukin-1?, heme oxygenase 1, aldo-keto reductase family 1, member C2, colony stimulating factor 3, leukemia inhibitory factor, heat shock 70 kDa protein, and combinations thereof, by administration of an effective amount of said compositions.
    Type: Grant
    Filed: November 20, 2009
    Date of Patent: April 26, 2011
    Assignees: New Chapter Inc., The Cleveland Clinic Foundation
    Inventors: Thomas Newmark, Mladen Golubic, Paul Schulick
  • Publication number: 20110020479
    Abstract: The inventive subject matter relates to methods for modulating an eicosanoid metabolic process in cells of an animal in need thereof, which comprises administering to the animal an amount of the inventive compositions effective for regulating the activity of an eicosanoid oxygenase. In particular, the inventive subject matter relates to methods for modulating arachadonic acid metabolism by administering an amount of the inventive compositions effective for regulating the activity of lipoxygenases and cyclooxygenases.
    Type: Application
    Filed: June 29, 2010
    Publication date: January 27, 2011
    Applicants: NEW CHAPTER INC., BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: Thomas NEWMARK, Paul SCHULICK, Robert NEWMAN, Bharat AGGARWAL
  • Publication number: 20100278947
    Abstract: The inventive subject matter relates to methods for modulating an eicosanoid metabolic process in cells of an animal in need thereof, which comprises administering to the animal an amount of the inventive compositions effective for regulating the activity of an eicosanoid oxygenase. In particular, the inventive subject matter relates to methods for modulating arachadonic acid metabolism by administering an amount of the inventive compositions effective for regulating the activity of lipoxygenases and cyclooxygenases.
    Type: Application
    Filed: December 29, 2008
    Publication date: November 4, 2010
    Applicants: New Chapter Inc., The University of Texas MD Anderson Cancer Center
    Inventors: Thomas Newmark, Paul Schulick, Robert Newman, Bharat Aggarwal
  • Patent number: 7744931
    Abstract: The inventive subject matter relates to methods for treating oral cancers, comprising administration of a composition comprising therapeutically effective amounts of supercritical extracts of rosemary, turmeric, oregano and ginger; and therapeutically effective amounts of hydroalcoholic extracts of holy basil, ginger, turmeric, Scutellaria baicalensis, rosemary, green tea, huzhang, Chinese goldthread, and barberry. The inventive subject matter further relates to methods for modulating gene expression of genes selected from the group consisting of interleukin-1?, interleukin-1?, heme oxygenase 1, aldo-keto reductase family 1, member C2, colony stimulating factor 3, leukemia inhibitory factor, heat shock 70 kDa protein, and combinations thereof, by administration of an effective amount of said compositions.
    Type: Grant
    Filed: November 8, 2007
    Date of Patent: June 29, 2010
    Assignees: New Chapter Inc., Board of Regents of the University of Texas System
    Inventors: Thomas Newmark, Robert Newman, Peiying Yang, Paul Schulick
  • Patent number: 7744934
    Abstract: The inventive subject matter relates to methods for treating prostate cancer, comprising administration of a composition comprising therapeutically effective amounts of supercritical extracts of rosemary, turmeric, oregano and ginger; and therapeutically effective amounts of hydroalcoholic extracts of holy basil, ginger, turmeric, Scutellaria baicalensis, rosemary, green tea, huzhang, Chinese goldthread, and barberry.
    Type: Grant
    Filed: December 29, 2008
    Date of Patent: June 29, 2010
    Assignees: New Chapter Inc., Board of Regents of the University of Texas System
    Inventors: Thomas Newmark, Paul Schulick, Aaron Katz
  • Publication number: 20100074977
    Abstract: The inventive subject matter relates to methods for treating glioblastoma, comprising administration of a composition comprising therapeutically effective amounts of supercritical extracts of rosemary, turmeric, oregano and ginger; and therapeutically effective amounts of hydroalcoholic extracts of holy basil, ginger, turmeric, Scutellaria baicalensis, rosemary, green tea, huzhang, Chinese goldthread, and barberry. The inventive subject matter further relates to methods for modulating gene expression of genes selected from the group consisting of interleukin-1?, interleukin-1?, heme oxygenase 1, aldo-keto reductase family 1, member C2, colony stimulating factor 3, leukemia inhibitory factor, heat shock 70 kDa protein, and combinations thereof, by administration of an effective amount of said compositions.
    Type: Application
    Filed: November 20, 2009
    Publication date: March 25, 2010
    Applicants: NEW CHAPTER, INC., The Cleveland Clinic Foundation
    Inventors: Thomas Newmark, Mladen Golubic, Paul Schulick
  • Patent number: 7622142
    Abstract: The inventive subject matter relates to methods for treating glioblastoma, comprising administration of a composition comprising therapeutically effective amounts of supercritical extracts of rosemary, turmeric, oregano and ginger; and therapeutically effective amounts of hydroalcoholic extracts of holy basil, ginger, turmeric, Scutellaria baicalensis, rosemary, green tea, huzhang, Chinese goldthread, and barberry. The inventive subject matter further relates to methods for modulating gene expression of genes selected from the group consisting of interleukin-1?, interleukin-1?, heme oxygenase 1, aldo-keto reductase family 1, member C2, colony stimulating factor 3, leukemia inhibitory factor, heat shock 70 kDa protein, and combinations thereof, by administration of an effective amount of said compositions.
    Type: Grant
    Filed: September 14, 2005
    Date of Patent: November 24, 2009
    Assignees: New Chapter Inc., The Cleveland Clinic Foundation
    Inventors: Thomas Newmark, Mladen Golubic, Paul Schulick
  • Patent number: 7563462
    Abstract: The inventive subject matter relates to methods for modulating an eicosanoid metabolic process in cells of an animal in need thereof, which comprises administering to the animal an amount of the inventive compositions effective for regulating the activity of an eicosanoid oxygenase. In particular, the inventive subject matter relates to methods for modulating arachadonic acid metabolism by administering an amount of the inventive compositions effective for regulating the activity of lipoxygenases and cyclooxygenases.
    Type: Grant
    Filed: June 14, 2006
    Date of Patent: July 21, 2009
    Assignees: The University of Texas MD Anderson Cancer Center, New Chapter Inc.
    Inventors: Thomas Newmark, Paul Schulick, Robert Newman, Bharat Aggarwal
  • Publication number: 20090110757
    Abstract: The inventive subject matter relates to methods for treating prostate cancer, comprising administration of a composition comprising therapeutically effective amounts of supercritical extracts of rosemary, turmeric, oregano and ginger; and therapeutically effective amounts of hydroalcoholic extracts of holy basil, ginger, turmeric, Scutellaria baicalensis, rosemary, green tea, huzhang, Chinese goldthread, and barberry.
    Type: Application
    Filed: December 29, 2008
    Publication date: April 30, 2009
    Applicant: New Chapter Inc.
    Inventors: Thomas Newmark, Paul Schulick, Aaron Katz
  • Patent number: 7470440
    Abstract: The inventive subject matter relates to methods for treating prostate cancer, comprising administration of a composition comprising therapeutically effective amounts of supercritical extracts of rosemary, turmeric, oregano and ginger; and therapeutically effective amounts of hydroalcoholic extracts of holy basil, ginger, turmeric, Scutellaria baicalensis, rosemary, green tea, huzhang, Chinese goldthread, and barberry.
    Type: Grant
    Filed: June 26, 2006
    Date of Patent: December 30, 2008
    Assignee: New Chapter, Inc.
    Inventors: Thomas Newmark, Paul Schulick, Aaron Katz
  • Publication number: 20080233218
    Abstract: The inventive subject matter relates to methods for treating oral cancers, comprising administration of a composition comprising therapeutically effective amounts of supercritical extracts of rosemary, turmeric, oregano and ginger; and therapeutically effective amounts of hydroalcoholic extracts of holy basil, ginger, turmeric, Scutellaria baicalensis, rosemary, green tea, huzhang, Chinese goldthread, and barberry. The inventive subject matter further relates to methods for modulating gene expression of genes selected from the group consisting of interleukin-1?, interleukin-1?, heme oxygenase 1, aldo-keto reductase family 1, member C2, colony stimulating factor 3, leukemia inhibitory factor, heat shock 70 kDa protein, and combinations thereof, by administration of an effective amount of said compositions.
    Type: Application
    Filed: November 8, 2007
    Publication date: September 25, 2008
    Inventors: Thomas Newmark, Robert Newman, Peiying Yang, Paul Schulick
  • Publication number: 20070042059
    Abstract: The inventive subject matter relates to methods for modulating an eicosanoid metabolic process in cells of an animal in need thereof, which comprises administering to the animal an amount of the inventive compositions effective for regulating the activity of an eicosanoid oxygenase. In particular, the inventive subject matter relates to methods for modulating arachadonic acid metabolism by administering an amount of the inventive compositions effective for regulating the activity of lipoxygenases and cyclooxygenases.
    Type: Application
    Filed: June 14, 2006
    Publication date: February 22, 2007
    Inventors: Thomas Newmark, Paul Schulick, Robert Newman, Bharat Aggarwal
  • Publication number: 20060240130
    Abstract: The inventive subject matter relates to methods for treating prostate cancer, comprising administration of a composition comprising therapeutically effective amounts of supercritical extracts of rosemary, turmeric, oregano and ginger; and therapeutically effective amounts of hydroalcoholic extracts of holy basil, ginger, turmeric, Scutellaria baicalensis, rosemary, green tea, huzhang, Chinese goldthread, and barberry.
    Type: Application
    Filed: June 26, 2006
    Publication date: October 26, 2006
    Inventors: Thomas Newmark, Paul Schulick, Aaron Katz
  • Patent number: 7070816
    Abstract: The inventive subject matter relates to methods for treating prostatic intraepithelial neoplasia, comprising administration of a composition comprising therapeutically effective amounts of supercritical extracts of rosemary, turmeric, oregano and ginger; and therapeutically effective amounts of hydroalcoholic extracts of holy basil, ginger, turmeric, Scutellaria baicalensis, rosemary, green tea, huzhang, Chinese goldthread, and barberry.
    Type: Grant
    Filed: December 5, 2003
    Date of Patent: July 4, 2006
    Assignee: New Chapter, Inc.
    Inventors: Thomas Newmark, Paul Schulick, Aaron Katz
  • Patent number: 7067159
    Abstract: The inventive subject matter relates to methods for treating prostate cancer, comprising administration of a composition comprising therapeutically effective amounts of supercritical extracts of rosemary, turmeric, oregano and ginger; and therapeutically effective amounts of hydroalcoholic extracts of holy basil, ginger, turmeric, Scutellaria baicalensis, rosemary, green tea, huzhang, Chinese goldthread, and barberry.
    Type: Grant
    Filed: December 5, 2003
    Date of Patent: June 27, 2006
    Assignee: New Chapter, Inc.
    Inventors: Thomas Newmark, Paul Schulick, Aaron Katz
  • Patent number: 7041321
    Abstract: A method is provided for effecting smoke detoxification in a human by using a composition that is made of effective amounts of supercritical extract and hydroalcoholic extract of turmeric.
    Type: Grant
    Filed: December 2, 2004
    Date of Patent: May 9, 2006
    Assignee: New Chapter, Inc.
    Inventors: Thomas Newmark, Paul Schulick
  • Publication number: 20060078631
    Abstract: The inventive subject matter relates to methods for treating glioblastoma, comprising administration of a composition comprising therapeutically effective amounts of supercritical extracts of rosemary, turmeric, oregano and ginger; and therapeutically effective amounts of hydroalcoholic extracts of holy basil, ginger, turmeric, Scutellaria baicalensis, rosemary, green tea, huzhang, Chinese goldthread, and barberry. The inventive subject matter further relates to methods for modulating gene expression of genes selected from the group consisting of interleukin-1?, interleukin-1?, heme oxygenase 1, aldo-keto reductase family 1, member C2, colony stimulating factor 3, leukemia inhibitory factor, heat shock 70 kDa protein, and combinations thereof, by administration of an effective amount of said compositions.
    Type: Application
    Filed: September 14, 2005
    Publication date: April 13, 2006
    Inventors: Thomas Newmark, Mladen Golubic, Paul Schulick