Abstract: The present invention is directed to compounds of formula IIa These compounds are considered useful for the treatment of diseases associated with leucine-rich repeat kinase 2 (LRRK2) such as Parkinson's disease. Furthermore, the invention relates to pharmaceutical compositions comprising said compounds.

Abstract: Bi-specific fusion proteins with therapeutic uses are provided, as well as pharmaceutical compositions comprising such fusion proteins, and methods for using such fusion proteins to repair or regenerate damaged or diseased tissue. The bi-specific fusion proteins generally comprise: (a) a targeting polypeptide domain that binds to a target molecule; and (b) an activator domain that detectably modulates tissue regeneration.

Abstract: Systems and methods are provided for tunable band pass filtering for Tunable RF Anti-Jamming Systems. A tunable notch filter includes a transmission line coupled to an antenna, a splitter, a band-stop filter, a polarity inverter, and a combiner. In operation, the band-stop filter suppresses predetermined frequency bands of a received signal creating a filtered signal, the polarity inverter creates an inverted signal, and the combiner combines the filtered and inverted signals to create a pass band including the predetermined frequency bands and suppressing frequency bands adjacent the predetermined frequency bands.

Abstract: A non-transitory computer readable medium for storing one or more sequences of one or more instructions for execution by one or more processors in a processing system to perform a method for determining a dichotomy for a parametric decision process, the instructions when executed by the one or more processors are presented. Embodiments can be configured to define a network having a plurality of members as inter-member coherency coupling represented by elements of a coherency matrix, wherein for each ith member the network includes an intensity value, Ii. Further embodiments may include determining non-diagonal elements Tij of the coherency matrix in which i?j and in which i and j represent ith and jth members of the network, and constructing diagonal kernels Ki or non-diagonal kernels Hi based on the non-diagonal elements Tij of the coherency matrix and intensity values (Ii) of the members.

Abstract: A tunable band pass filtering for Tunable RF Anti-Jamming Systems is provided. Such embodiments include a first bandpass filter tunable to a first frequency band and a second bandpass filter coupled to the first bandpass filter and tunable to a second frequency band. In addition, a plurality of tunable passive components may be adapted to tune the first and second bandpass filters to the first and second frequency bands, respectively, thereby creating a multiband pass band signal to include the first and second frequency bands and attentuating frequency bands adjacent to the first and second frequency bands.

Abstract: Systems and methods for controlling access to relationship information in a social network are described. One described method comprises receiving a request from an observer for relationship information indicating at least a first relationship between a target in a social network and a second entity in the social network, identifying at least a first privacy rule for the first relationship, and outputting at least part of the relationship information to the observer if the first privacy rule is satisfied.

Abstract: A micro-payment system has buyers, sellers, and a broker. The buyers establish accounts with the broker and provide payment information allowing the broker to invoice the buyers. The sellers establish accounts with the brokers and specify terms for accessing items, including electronic content, available from the sellers. The sellers also provide payment information that allows the broker to credit the sellers for sales of the items. The broker aggregates the buyers' micro-payment purchases and invoices the buyers. The broker also aggregates the sellers' micro-payment sales and credits the sellers.

Abstract: A micro-payment system has buyers, sellers, and a broker. The buyers establish accounts with the broker and provide payment information allowing the broker to invoice the buyers. The sellers establish accounts with the brokers and specify terms for accessing items, including electronic content, available from the sellers. The sellers also provide payment information that allows the broker to credit the sellers for sales of the items. The broker aggregates the buyers' micro-payment purchases and invoices the buyers. The broker also aggregates the sellers' micro-payment sales and credits the sellers.

Abstract: A micro-payment system has buyers, sellers, and a broker. The buyers establish accounts with the broker and provide payment information allowing the broker to invoice the buyers. The sellers establish accounts with the brokers and specify terms for accessing items, including electronic content, available from the sellers. The sellers also provide payment information that allows the broker to credit the sellers for sales of the items. The broker aggregates the buyers' micro-payment purchases and invoices the buyers. The broker also aggregates the sellers' micro-payment sales and credits the sellers.

Abstract: A micro-payment system has buyers, sellers, and a broker. The buyers establish accounts with the broker and provide payment information allowing the broker to invoice the buyers. The sellers establish accounts with the brokers and specify terms for accessing items, including electronic content, available from the sellers. The sellers also provide payment information that allows the broker to credit the sellers for sales of the items. The broker aggregates the buyers' micro-payment purchases and invoices the buyers. The broker also aggregates the sellers' micro-payment sales and credits the sellers.

Abstract: The invention concerns a hearing aid with anti feed back system. The hearing aid according to the invention comprises: a signal path from at least one input transducer to an output transducer, a signal processing unit, acoustic environment detection means, means for generating input to the setting of signal processing parameters to be used in the signal processing unit based on either manual input or output from the acoustic environment detection means, means for generating an alert signal to the anti feed back system whenever one or more preselected input to the generation of signal processing parameters undergoes changes.

Abstract: Independent software integration is described. In an embodiment, source code of independently developed software is received for integration into a developing software build and the source code is maintained as a limited-access resource to protect proprietary information contained within the source code. The source code is tested independent of the developing software build for error-free integration into the developing software build. Binary data is generated from the source code, and the binary data is integrated into the developing software build such that the independently developed software executes as an integrated component when the software build is complete.

Abstract: The present invention relates to a method of preparing heterocyclic organic com-pounds involving intramolecular formation of an N-acyliminium ion and an in-tramolecular Pictet-Spengler reaction. The invention furthermore discloses precursor molecules useful for the method and methods of preparing these precursor mole-cules. The invention also relates to heterocyclic organic compounds prepared by the methods, libraries of such heterocyclic organic compound and methods of preparing them, as well as to various uses of the heterocyclic organic compounds.

Abstract: Process and apparatus for the preparation of synthesis gas by catalytic steam and/or CO2 reforming of a hydrocarbon feedstock comprising the following steps: (a) heating the reaction mixture of hydrocarbon and steam and/or CO2 in a heated steam reforming unit integrated with the flue gas containing waste heat section from the fired tubular reformer in which reforming of the reaction mixture takes place by contact with a solid reforming catalyst (b) feeding the partially steam reformed mixture to the fired tubular reformer and further reforming the mixture to the desired composition and temperature, wherein the heated steam reforming unit comprises a piping system containing reaction sections with solid reforming catalyst comprising catalyst pellets and/or catalysed structured elements, the piping system being part of the process gas piping system integrated with the flue gas-containing waste heat section.

Abstract: A micro-payment system has buyers, sellers, and a broker. The buyers establish accounts with the broker and provide payment information allowing the broker to invoice the buyers. The sellers establish accounts with the brokers and specify terms for accessing items, including electronic content, available from the sellers. The sellers also provide payment information that allows the broker to credit the sellers for sales of the items. The broker aggregates the buyers' micro-payment purchases and invoices the buyers. The broker also aggregates the sellers' micro-payment sales and credits the sellers.

Abstract: A process for making an integral one piece rotor liner for use with a high speed rotor. The liner has an inner chamber and an annular chamber designed to operate in conjunction with the rotor operation to automatically allow fluid communication between the respective chambers during centrifugation and automatically establish a seal between the respective chambers subsequent to the centrifugation operation. The process for making the one piece rotor liner generally comprises a first step of molding the liner in an intermediate elongated configuration wherein the inner chamber portion is integrally joined to and spaced from the annular chamber portion of the liner by a reversing section. The general configuration of the inner chamber is located at one end of the elongated liner shape and the general configuration of the annular chamber is located at the other end of the elongated liner.