Patents by Inventor Thomas O'Sullivan

Thomas O'Sullivan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12121879
    Abstract: The invention concerns polymeric media based on modified natural polysaccharides for removing one or both of Anti-A Antibodies and Anti-B Antibodies from human blood or plasma, the media comprising one or both of (i) a polymeric solid support with a blood group A Antigen ligand attached to the solid support at a ligand loading between 1-5 mg/mL of solid support, and wherein the media is stable under physiological pH conditions, and (ii) a polymeric solid support with a blood group B Antigen ligand attached to the solid support at a ligand loading between 1-5 mg/mL of solid support, and wherein the media is stable under physiological pH conditions.
    Type: Grant
    Filed: December 2, 2019
    Date of Patent: October 22, 2024
    Assignee: CytoSorbents, Inc.
    Inventors: Tamaz Guliashvili, Maryann Gruda, Thomas Golobish, David James, Karl-Gustav Ruggeberg, Pamela O'Sullivan, Sarah Patterson
  • Patent number: 11160470
    Abstract: In accordance with various embodiments herein, disclosed herein is an apparatus comprising an imaging probe-based device operably linked to an automated tracking system. Furthermore, in various embodiments, the apparatus may be used to track the position and movement of a handheld imaging probe, including with respect to a subject's 3D surface profile. In one embodiment, a device may be used to track the position and movement of a handheld imaging probe with respect to a subject's 3D surface profile, while simultaneously acquiring optical data.
    Type: Grant
    Filed: May 31, 2016
    Date of Patent: November 2, 2021
    Assignee: The Regents of the University of California
    Inventors: Bruce J. Tromberg, Kyle Cutler, Chris Van Wagenen, Seung-ha Lee, Thomas O'Sullivan, Gopi Meenakshisundaram, Aditi Majumder, Albert Cerussi
  • Patent number: 10827974
    Abstract: A quantitative, non-invasive optical spectroscopy technique for measuring dynamic changes in adipose tissue structure and metabolism in vivo. The technique requires multiple wavelengths of light in the near-infrared (650-1000 nm). Using these wavelengths of light, adipose tissue is illuminated and light that returns to a photodetector is analyzed. From the return signals, the absorption and reduced scattering coefficients (?a and ?s?) at each wavelength are calculated. The obtained ?a and ?s? values allow for quantification of biomarkers and indices which allow for measurement of fat composition and metabolism. The concentration of oxy- and deoxy-hemoglobin, the fractional water and lipid content, and information about the size distribution of light scatterers in the adipose tissue are also determined. A detailed and quantitative understanding of fat composition and metabolism is thereby provided which describes the effectiveness of interventions to improve the health of a patient.
    Type: Grant
    Filed: January 20, 2017
    Date of Patent: November 10, 2020
    Assignee: The Regents of the University of California
    Inventors: Robert Warren, Goutham Ganesan, Thomas O'Sullivan, Shaista Malik, Bruce J. Tromberg, Pietro Galassetti
  • Publication number: 20170209089
    Abstract: A quantitative, non-invasive optical spectroscopy technique for measuring dynamic changes in adipose tissue structure and metabolism in vivo. The technique requires multiple wavelengths of light in the near-infrared (650-1000 nm). Using these wavelengths of light, adipose tissue is illuminated and light that returns to a photodetector is analyzed. From the return signals, the absorption and reduced scattering coefficients (?a and ?s?) at each wavelength are calculated. The obtained pa and ?s? values allow for quantification of biomarkers and indices which allow for measurement of fat composition and metabolism. The concentration of oxy- and deoxy-hemoglobin, the fractional water and lipid content, and information about the size distribution of light scatterers in the adipose tissue are also determined. A detailed and quantitative understanding of fat composition and metabolism is thereby provided which describes the effectiveness of interventions to improve the health of a patient.
    Type: Application
    Filed: January 20, 2017
    Publication date: July 27, 2017
    Inventors: Robert Warren, Goutham Ganesan, Thomas O'Sullivan, Shaista Malik, Bruce J. Tromberg, Pietro Galassetti
  • Publication number: 20160345858
    Abstract: In accordance with various embodiments herein, disclosed herein is an apparatus comprising an imaging probe-based device operably linked to an automated tracking system. Furthermore, in various embodiments, the apparatus may be used to track the position and movement of a handheld imaging probe, including with respect to a subject's 3D surface profile. In one embodiment, a device may be used to track the position and movement of a handheld imaging probe with respect to a subject's 3D surface profile, while simultaneously acquiring optical data.
    Type: Application
    Filed: May 31, 2016
    Publication date: December 1, 2016
    Applicant: The Regents of the University of California
    Inventors: Bruce J. Tromberg, Kyle Cutler, Chris Van Wagenen, Seung-ha Lee, Thomas O'Sullivan, Gopi Meenakshisundaram, Aditi Majumder, Albert Cerussi
  • Patent number: 9171069
    Abstract: Method, apparatus, and computer-readable medium are provided for analyzing a document including text. In one example, a method for identifying patterns in a document is described. The method includes identifying a plurality of candidate phrases in the document based on candidate identification criteria, grouping the candidate phrases of the plurality of candidate phrases with a phrase family based on family criteria and comparison between candidate phrases of the plurality of candidate phrases to obtain consistent phrases, and, for remaining phrases not meeting all of the candidate identification criteria, associating at least one of the remaining phrases with a phrase family based on inconsistent phrase criteria to obtain inconsistent phrases. Identified in this manner, the inconsistent phrase may be displayed via a user interface to permit a user the opportunity to determine whether an inconsistent phrase requires modification.
    Type: Grant
    Filed: July 31, 2012
    Date of Patent: October 27, 2015
    Assignee: FREEDOM SOLUTIONS GROUP, LLC
    Inventors: Thomas O'Sullivan, Andrzej Jachowicz
  • Publication number: 20140040270
    Abstract: Method, apparatus, and computer-readable medium are provided for analyzing a document including text. In one example, a method for identifying patterns in a document is described. The method includes identifying a plurality of candidate phrases in the document based on candidate identification criteria, grouping the candidate phrases of the plurality of candidate phrases with a phrase family based on family criteria and comparison between candidate phrases of the plurality of candidate phrases to obtain consistent phrases, and, for remaining phrases not meeting all of the candidate identification criteria, associating at least one of the remaining phrases with a phrase family based on inconsistent phrase criteria to obtain inconsistent phrases. Identified in this manner, the inconsistent phrase may be displayed via a user interface to permit a user the opportunity to determine whether an inconsistent phrase requires modification.
    Type: Application
    Filed: July 31, 2012
    Publication date: February 6, 2014
    Applicant: Freedom Solutions Group, LLC, d/b/a Microsystems
    Inventors: Thomas O'Sullivan, Andrzej Jachowicz
  • Publication number: 20130174029
    Abstract: Method, apparatus, and computer-readable medium are provided for analyzing a document including text. In one example, the method includes obtaining the text from the document to provide obtained text, generating a plurality of indices representative of the obtained text, generating a user interface including at least a portion of the obtained text based on the plurality of indices, monitoring the document for a change in the text, updating the plurality of indices to reflect the change to provide updated indices in response to detecting a change in the text, updating the plurality of indices to reflect the change to provide updated indices, and generating an updated user interface based on the updated indices without user intervention.
    Type: Application
    Filed: January 4, 2012
    Publication date: July 4, 2013
    Applicant: Freedom Solutions Group, LLC d/b/a Microsystems
    Inventors: Thomas O'Sullivan, Andrzej Jachowicz
  • Publication number: 20130174030
    Abstract: Method, apparatus, and computer-readable medium are provided for analyzing a document including text. In one example, the method includes obtaining the text from the document to provide obtained text, generating a plurality of indices representative of the obtained text, generating a user interface including at least a portion of the obtained text that includes an abbreviation based on the plurality of indices, monitoring the document for a change in the text, updating the plurality of indices to reflect the change to provide updated indices in response to detecting a change in the text, updating the plurality of indices to reflect the change to provide updated indices, and generating an updated user interface based on the updated indices without user intervention.
    Type: Application
    Filed: June 25, 2012
    Publication date: July 4, 2013
    Applicant: Freedom Solutions Group, LLC, d/b/a Microsystems
    Inventors: Thomas O'Sullivan, Andrzej Jachowicz, Toby L. Adamson
  • Publication number: 20070113519
    Abstract: A method of repairing and renewing a manhole chimney utilizes a circumferentially stretchable liner sleeve which is inserted into the manhole and pressed by an inflatable bladder into engagement with the walls of the manhole chimney. The sleeve is coated with an uncured resin, which is allowed to cure as the sleeve is pressed against the chimney walls, thereby attaching the sleeve to the walls of the manhole chimney. The stretchable sleeve eliminates air spaces between the sleeve and the chimney walls, and precludes formation of undesirable folds in the sleeve. The sleeve stretches circumferentially up to 150% of its unstretched diameter, while having a substantially unstretchable length.
    Type: Application
    Filed: November 23, 2005
    Publication date: May 24, 2007
    Applicant: LMK ENTERPRISES, INC.
    Inventors: Larry Kiest, Jason Bartlett, Thomas O'Sullivan, Raymond Greek, Timothy Back, Donald Betzold
  • Publication number: 20050084762
    Abstract: A hybrid gelled-electrolyte VRLA battery and method for its manufacture are disclosed. In accordance with the present invention, the VRLA battery includes both an AGM separator and a first gelled electrolyte. In accordance with the method, a first silica-electrolyte mixture is placed in contact with the battery plates and AGM separator before formation. During plate formation, the mixture gels to form the first gelled electrolyte. In some embodiments, after forming the plates, a smaller amount of a second gelled electrolyte is added to the battery jar.
    Type: Application
    Filed: October 15, 2003
    Publication date: April 21, 2005
    Inventors: Frank Vaccaro, Thomas O'Sullivan, Bich Le