Patents by Inventor Thomas O'Sullivan
Thomas O'Sullivan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12121879Abstract: The invention concerns polymeric media based on modified natural polysaccharides for removing one or both of Anti-A Antibodies and Anti-B Antibodies from human blood or plasma, the media comprising one or both of (i) a polymeric solid support with a blood group A Antigen ligand attached to the solid support at a ligand loading between 1-5 mg/mL of solid support, and wherein the media is stable under physiological pH conditions, and (ii) a polymeric solid support with a blood group B Antigen ligand attached to the solid support at a ligand loading between 1-5 mg/mL of solid support, and wherein the media is stable under physiological pH conditions.Type: GrantFiled: December 2, 2019Date of Patent: October 22, 2024Assignee: CytoSorbents, Inc.Inventors: Tamaz Guliashvili, Maryann Gruda, Thomas Golobish, David James, Karl-Gustav Ruggeberg, Pamela O'Sullivan, Sarah Patterson
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Patent number: 11160470Abstract: In accordance with various embodiments herein, disclosed herein is an apparatus comprising an imaging probe-based device operably linked to an automated tracking system. Furthermore, in various embodiments, the apparatus may be used to track the position and movement of a handheld imaging probe, including with respect to a subject's 3D surface profile. In one embodiment, a device may be used to track the position and movement of a handheld imaging probe with respect to a subject's 3D surface profile, while simultaneously acquiring optical data.Type: GrantFiled: May 31, 2016Date of Patent: November 2, 2021Assignee: The Regents of the University of CaliforniaInventors: Bruce J. Tromberg, Kyle Cutler, Chris Van Wagenen, Seung-ha Lee, Thomas O'Sullivan, Gopi Meenakshisundaram, Aditi Majumder, Albert Cerussi
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Patent number: 10827974Abstract: A quantitative, non-invasive optical spectroscopy technique for measuring dynamic changes in adipose tissue structure and metabolism in vivo. The technique requires multiple wavelengths of light in the near-infrared (650-1000 nm). Using these wavelengths of light, adipose tissue is illuminated and light that returns to a photodetector is analyzed. From the return signals, the absorption and reduced scattering coefficients (?a and ?s?) at each wavelength are calculated. The obtained ?a and ?s? values allow for quantification of biomarkers and indices which allow for measurement of fat composition and metabolism. The concentration of oxy- and deoxy-hemoglobin, the fractional water and lipid content, and information about the size distribution of light scatterers in the adipose tissue are also determined. A detailed and quantitative understanding of fat composition and metabolism is thereby provided which describes the effectiveness of interventions to improve the health of a patient.Type: GrantFiled: January 20, 2017Date of Patent: November 10, 2020Assignee: The Regents of the University of CaliforniaInventors: Robert Warren, Goutham Ganesan, Thomas O'Sullivan, Shaista Malik, Bruce J. Tromberg, Pietro Galassetti
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Publication number: 20170209089Abstract: A quantitative, non-invasive optical spectroscopy technique for measuring dynamic changes in adipose tissue structure and metabolism in vivo. The technique requires multiple wavelengths of light in the near-infrared (650-1000 nm). Using these wavelengths of light, adipose tissue is illuminated and light that returns to a photodetector is analyzed. From the return signals, the absorption and reduced scattering coefficients (?a and ?s?) at each wavelength are calculated. The obtained pa and ?s? values allow for quantification of biomarkers and indices which allow for measurement of fat composition and metabolism. The concentration of oxy- and deoxy-hemoglobin, the fractional water and lipid content, and information about the size distribution of light scatterers in the adipose tissue are also determined. A detailed and quantitative understanding of fat composition and metabolism is thereby provided which describes the effectiveness of interventions to improve the health of a patient.Type: ApplicationFiled: January 20, 2017Publication date: July 27, 2017Inventors: Robert Warren, Goutham Ganesan, Thomas O'Sullivan, Shaista Malik, Bruce J. Tromberg, Pietro Galassetti
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Publication number: 20160345858Abstract: In accordance with various embodiments herein, disclosed herein is an apparatus comprising an imaging probe-based device operably linked to an automated tracking system. Furthermore, in various embodiments, the apparatus may be used to track the position and movement of a handheld imaging probe, including with respect to a subject's 3D surface profile. In one embodiment, a device may be used to track the position and movement of a handheld imaging probe with respect to a subject's 3D surface profile, while simultaneously acquiring optical data.Type: ApplicationFiled: May 31, 2016Publication date: December 1, 2016Applicant: The Regents of the University of CaliforniaInventors: Bruce J. Tromberg, Kyle Cutler, Chris Van Wagenen, Seung-ha Lee, Thomas O'Sullivan, Gopi Meenakshisundaram, Aditi Majumder, Albert Cerussi
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Patent number: 9171069Abstract: Method, apparatus, and computer-readable medium are provided for analyzing a document including text. In one example, a method for identifying patterns in a document is described. The method includes identifying a plurality of candidate phrases in the document based on candidate identification criteria, grouping the candidate phrases of the plurality of candidate phrases with a phrase family based on family criteria and comparison between candidate phrases of the plurality of candidate phrases to obtain consistent phrases, and, for remaining phrases not meeting all of the candidate identification criteria, associating at least one of the remaining phrases with a phrase family based on inconsistent phrase criteria to obtain inconsistent phrases. Identified in this manner, the inconsistent phrase may be displayed via a user interface to permit a user the opportunity to determine whether an inconsistent phrase requires modification.Type: GrantFiled: July 31, 2012Date of Patent: October 27, 2015Assignee: FREEDOM SOLUTIONS GROUP, LLCInventors: Thomas O'Sullivan, Andrzej Jachowicz
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Publication number: 20140040270Abstract: Method, apparatus, and computer-readable medium are provided for analyzing a document including text. In one example, a method for identifying patterns in a document is described. The method includes identifying a plurality of candidate phrases in the document based on candidate identification criteria, grouping the candidate phrases of the plurality of candidate phrases with a phrase family based on family criteria and comparison between candidate phrases of the plurality of candidate phrases to obtain consistent phrases, and, for remaining phrases not meeting all of the candidate identification criteria, associating at least one of the remaining phrases with a phrase family based on inconsistent phrase criteria to obtain inconsistent phrases. Identified in this manner, the inconsistent phrase may be displayed via a user interface to permit a user the opportunity to determine whether an inconsistent phrase requires modification.Type: ApplicationFiled: July 31, 2012Publication date: February 6, 2014Applicant: Freedom Solutions Group, LLC, d/b/a MicrosystemsInventors: Thomas O'Sullivan, Andrzej Jachowicz
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Publication number: 20130174029Abstract: Method, apparatus, and computer-readable medium are provided for analyzing a document including text. In one example, the method includes obtaining the text from the document to provide obtained text, generating a plurality of indices representative of the obtained text, generating a user interface including at least a portion of the obtained text based on the plurality of indices, monitoring the document for a change in the text, updating the plurality of indices to reflect the change to provide updated indices in response to detecting a change in the text, updating the plurality of indices to reflect the change to provide updated indices, and generating an updated user interface based on the updated indices without user intervention.Type: ApplicationFiled: January 4, 2012Publication date: July 4, 2013Applicant: Freedom Solutions Group, LLC d/b/a MicrosystemsInventors: Thomas O'Sullivan, Andrzej Jachowicz
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Publication number: 20130174030Abstract: Method, apparatus, and computer-readable medium are provided for analyzing a document including text. In one example, the method includes obtaining the text from the document to provide obtained text, generating a plurality of indices representative of the obtained text, generating a user interface including at least a portion of the obtained text that includes an abbreviation based on the plurality of indices, monitoring the document for a change in the text, updating the plurality of indices to reflect the change to provide updated indices in response to detecting a change in the text, updating the plurality of indices to reflect the change to provide updated indices, and generating an updated user interface based on the updated indices without user intervention.Type: ApplicationFiled: June 25, 2012Publication date: July 4, 2013Applicant: Freedom Solutions Group, LLC, d/b/a MicrosystemsInventors: Thomas O'Sullivan, Andrzej Jachowicz, Toby L. Adamson
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Publication number: 20070113519Abstract: A method of repairing and renewing a manhole chimney utilizes a circumferentially stretchable liner sleeve which is inserted into the manhole and pressed by an inflatable bladder into engagement with the walls of the manhole chimney. The sleeve is coated with an uncured resin, which is allowed to cure as the sleeve is pressed against the chimney walls, thereby attaching the sleeve to the walls of the manhole chimney. The stretchable sleeve eliminates air spaces between the sleeve and the chimney walls, and precludes formation of undesirable folds in the sleeve. The sleeve stretches circumferentially up to 150% of its unstretched diameter, while having a substantially unstretchable length.Type: ApplicationFiled: November 23, 2005Publication date: May 24, 2007Applicant: LMK ENTERPRISES, INC.Inventors: Larry Kiest, Jason Bartlett, Thomas O'Sullivan, Raymond Greek, Timothy Back, Donald Betzold
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Publication number: 20050084762Abstract: A hybrid gelled-electrolyte VRLA battery and method for its manufacture are disclosed. In accordance with the present invention, the VRLA battery includes both an AGM separator and a first gelled electrolyte. In accordance with the method, a first silica-electrolyte mixture is placed in contact with the battery plates and AGM separator before formation. During plate formation, the mixture gels to form the first gelled electrolyte. In some embodiments, after forming the plates, a smaller amount of a second gelled electrolyte is added to the battery jar.Type: ApplicationFiled: October 15, 2003Publication date: April 21, 2005Inventors: Frank Vaccaro, Thomas O'Sullivan, Bich Le