Abstract: The disclosure presents a system and method for preventing pharmacy errors for a prescription. The system and method receives prescription data comprising medication data and direction data for the delivery of medication identified within the medication data for the prescription, transmits the prescription data to a pharmacy computer memory associated with a pharmacy prescription entry and fill computer. The system and method further compares, at the pharmacy entry and fill computer, the direction data for the prescription to error prevention keyword data for the medication data, wherein the error prevention keyword data is stored in an error prevention keyword database associated with the pharmacy entry and fill computer and the pharmacy computer memory. A possible directions error message is transmitted to a display of a communication device for viewing by pharmacy personnel in response to the comparison.