Patents by Inventor Thomas Ortmann
Thomas Ortmann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20250137887Abstract: A sample transport device for transporting a fluidic sample, in particular for an analyzer for analyzing the fluidic sample, includes a sample receptacle for receiving and/or dispensing the fluidic sample; a moving device, in particular a robot arm, for moving the sample receptacle, and a pumping element arranged to be moved by the moving device to perform and/or trigger a pumping operation.Type: ApplicationFiled: October 30, 2024Publication date: May 1, 2025Inventors: Blasius Nocon, Thomas Ortmann
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Patent number: 12235248Abstract: An injector, for injecting a fluidic sample into a flow path between a fluid drive and a sample separation unit, includes a sample accommodation volume, a sample drive, and a fluidic valve switchable to selectively couple the volume with the flow path or decouple the volume from the flow path. In an injection switching state, the fluid drive, the separation unit and the sample drive are coupled by the valve so that fluid driven by the sample drive and flowing from the volume to the separation unit and further fluid driven by the fluid drive and flowing from the fluid drive to the separation unit are combined at a fluidic connection upstream of the separation unit. A control unit controls an outlet flow rate value according to which a combination of the mobile phase and the fluidic sample is driven through the separation unit.Type: GrantFiled: September 18, 2023Date of Patent: February 25, 2025Assignee: Agilent Technologies, Inc.Inventors: Daniel Thielsch, Thomas Ortmann, Sam Wouters
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Publication number: 20250060340Abstract: A configurable injector for injecting a fluidic sample in a separation path of a sample separation apparatus includes a sample accommodation volume for accommodating the fluidic sample to be injected into the separation path, a valve arrangement fluidically couplable with the separation path, fluidically coupled with the sample accommodation volume, and being controllable for injecting the fluidic sample into the separation path, an input interface configured for receiving input data indicative of an injection profile of an injector to be emulated by the configurable injector, and a control unit configured for controlling the configurable injector, in particular the valve arrangement, so that the configurable injector is operated in accordance with the injection profile to thereby emulate the injector to be emulated.Type: ApplicationFiled: October 30, 2024Publication date: February 20, 2025Inventor: Thomas Ortmann
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Patent number: 12174160Abstract: A fluid processing apparatus includes a first fluid processing unit and a second fluid processing unit. A fluid unit is fluidically coupled to the first fluid processing unit and includes a first buffering unit configured for buffering fluid, and/or a mask flow source configured for providing a mask fluid or a flow thereof. A first coupling point is fluidically coupled between the first fluid processing unit and the fluid unit. A modulation unit is configured, selectively, for withdrawing fluid from the first coupling point, or for transferring withdrawn fluid into the second fluid processing unit. The apparatus may be utilized for chromatography.Type: GrantFiled: July 30, 2020Date of Patent: December 24, 2024Assignee: Agilent Technologies, Inc.Inventors: Dwight Robert Stoll, Konstantin Shoykhet, Thomas Ortmann, Stephan Buckenmaier, Sascha Lege
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Patent number: 12163932Abstract: A configurable injector for injecting a fluidic sample in a separation path of a sample separation apparatus includes a sample accommodation volume for accommodating the fluidic sample to be injected into the separation path, a valve arrangement fluidically couplable with the separation path, fluidically coupled with the sample accommodation volume, and being controllable for injecting the fluidic sample into the separation path, an input interface configured for receiving input data indicative of an injection profile of an injector to be emulated by the configurable injector, and a control unit configured for controlling the configurable injector, in particular the valve arrangement, so that the configurable injector is operated in accordance with the injection profile to thereby emulate the injector to be emulated.Type: GrantFiled: December 14, 2018Date of Patent: December 10, 2024Assignee: Agilent Technologies, Inc.Inventor: Thomas Ortmann
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Patent number: 12140575Abstract: A sample management device which comprises a source flow path in which a fluidic sample can flow, a volume flow adjustment unit configured for adjusting a volume flow of the fluidic sample to be branched off from the source flow path at a fluidic coupling point, and a fluidic valve fluidically coupled with the source flow path and with the volume flow adjustment unit, wherein the fluidic valve is switchable into a branch off state in which the fluidic coupling point is established within the source flow path to branch off an adjustable volume of the fluidic sample from the source flow path via the fluidic coupling point while a flow of the fluidic sample in the source flow path continues.Type: GrantFiled: May 26, 2022Date of Patent: November 12, 2024Assignee: Agilent Technologies, Inc.Inventors: Thomas Ortmann, Daniel Thielsch
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Patent number: 12078619Abstract: An injector, for injecting a fluidic sample in at least one selected one of a first sample separation apparatus and a second sample separation apparatus, includes a valve arrangement fluidically connectable to the first sample separation apparatus and the second sample separation apparatus, a sample accommodation volume for accommodating the fluidic sample, and a control unit configured for controlling the valve arrangement so that fluidic sample in the sample accommodation volume is selectively injectable into the selected first sample separation apparatus and/or second sample separation apparatus.Type: GrantFiled: October 26, 2018Date of Patent: September 3, 2024Assignee: Agilent Technologies, Inc.Inventor: Thomas Ortmann
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Publication number: 20240241086Abstract: A switching unit is configured for selectively fluidically coupling a sampling volume, a sampling drive, a mobile phase drive, and a separating device. In a sample load configuration, the switching unit is configured for fluidically coupling the sampling volume and the sampling drive, for moving the fluidic sample into the sampling volume. In a decouple configuration, the switching unit is configured for fluidically coupling the sampling volume between the sampling drive and the separating device, while the mobile phase drive is fluidically decoupled from the separating device. In a sample introduction configuration, the switching unit is configured for fluidically coupling the mobile phase drive, the sampling volume, and the separating device for introducing at least an amount of the fluidic sample stored in the sampling volume into the mobile phase for fluid separation by the separating device.Type: ApplicationFiled: May 17, 2022Publication date: July 18, 2024Inventors: Thomas Ortmann, Dominik Ruf
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Publication number: 20240201143Abstract: A sample separation device includes a separation path and a control unit. The separation path is between a fluid drive and a sample separation unit, and is configured to inject a fluidic sample in an injector path into a mobile phase in the separation path driven by the fluid drive to the sample separation unit for chromatographically separating the fluidic sample. The control unit is configured to control blocking the injector path or at least a partial path thereof, generating an overpressure in the blocked injector path or the partial path thereof by a pressure source, and subsequently fluidically coupling the injector path or the partial path thereof to a region of lower pressure than the overpressure to generate an expansion stroke for releasing unwanted components from the injector path.Type: ApplicationFiled: February 1, 2024Publication date: June 20, 2024Inventors: Thomas Ortmann, Martin Seifried, Sam Wouters, Irina Spuling
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Patent number: 11946913Abstract: An injector is configured for injecting a fluidic sample from an injector path into a mobile phase in a separation path between a fluid drive and a sample separation unit of a sample separation device. The injector includes a control unit configured for generating a first overpressure in a blocked first partial path of the injector path by a first pressure source, for generating a second overpressure in a blocked second partial path of the injector path by a second pressure source, for subsequently fluidically coupling the first partial path with the second partial path for generating an expansion stroke for releasing a gas bubble in the injector path, and for rinsing the released gas bubble from the injector path.Type: GrantFiled: April 27, 2022Date of Patent: April 2, 2024Assignee: Agilent Technologies, Inc.Inventors: Thomas Ortmann, Martin Seifried, Sam Wouters, Irina Spuling
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Patent number: 11931918Abstract: A microfluidic component for a sample separation apparatus includes a component body including ceramic and at least one microfluidic structure in the component body. The component body is manufactured by additive manufacturing, in particular by three-dimensional printing.Type: GrantFiled: November 19, 2018Date of Patent: March 19, 2024Assignee: Agilent Technologies, Inc.Inventors: Darijo Zeko, Tony Ziegler, Thomas Ortmann
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Publication number: 20240077460Abstract: An injector, for injecting a fluidic sample into a flow path between a fluid drive and a sample separation unit, includes a sample accommodation volume, a sample drive, and a fluidic valve switchable to selectively couple the volume with the flow path or decouple the volume from the flow path. In an injection switching state, the fluid drive, the separation unit and the sample drive are coupled by the valve so that fluid driven by the sample drive and flowing from the volume to the separation unit and further fluid driven by the fluid drive and flowing from the fluid drive to the separation unit are combined at a fluidic connection upstream of the separation unit. A control unit controls a pressure of the fluid and/or the further fluid during injecting.Type: ApplicationFiled: September 18, 2023Publication date: March 7, 2024Inventors: Daniel Thielsch, Thomas Ortmann, Sam Wouters
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Patent number: 11921093Abstract: A mounting device for mounting a sample separation unit configured for separating, preferably chromatographically separating, compounds in a fluidic sample includes a first fluid connector configured for being mechanically and fluidically coupled with a first fluid interface of the sample separation unit, a second fluid connector configured for being mechanically and fluidically coupled with a second fluid interface of the sample separation unit, and a swivel mechanism configured for swivelling the first fluid connector between a mounting orientation for mounting the first fluid interface of the sample separation unit at the first fluid connector and an alignment orientation for aligning the second fluid interface of the mounted sample separation unit with the second fluid connector for subsequently coupling the second fluid interface with the second fluid connector.Type: GrantFiled: January 25, 2022Date of Patent: March 5, 2024Assignee: Agilent Technologies, Inc.Inventors: Daniela Loraing, Lena Höninger, Uwe Effelsberg, Andreas Otto, Ansgar Waldbaur, Armin Steinke, Thomas Ortmann, Michael Lang
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Publication number: 20240027407Abstract: A fluid valve, for a sample separation device such as for liquid chromatography, includes a rotor, a stator, and external terminals for fluidically connecting one or more components. By rotating the rotor, different fluidic coupling and/or decoupling states between components are adjustable. Ports are connectable with one or more external terminals. A first channel is formed along a first circular path. A second channel includes a first coupling point located on the first circular path and a second coupling point located on a second circular path. By rotating the rotor, a fluidic coupling between a first port and a second port can be established, by the first channel being connected with the first port and at least the first coupling point with the second channel, and by the second channel being connected at least via the second coupling point with the second port.Type: ApplicationFiled: December 7, 2021Publication date: January 25, 2024Inventors: Konstantin Shoykhet, Thomas Ortmann
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Publication number: 20240011957Abstract: A sampling unit is fluidically coupled to a source. The sampling unit is configured for receiving a fluidic sample from the source and chromatographically separating the received fluidic sample. The sampling unit is operated to introduce a test sample into the source. At least a portion of the introduced test sample from the source is received into the sampling unit, and the received portion of the test sample is chromatographically separated in the sampling unit.Type: ApplicationFiled: November 19, 2021Publication date: January 11, 2024Inventors: Dominik Ruf, Thomas Ortmann
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Patent number: 11835495Abstract: An injector, for injecting a fluidic sample into a flow path between a fluid drive and a sample separation unit, includes a sample accommodation volume, a sample drive, and a fluidic valve switchable to selectively couple the volume with the flow path or decouple the volume from the flow path. In an injection switching state, the fluid drive, the separation unit and the sample drive are coupled by the valve so that fluid driven by the sample drive and flowing from the volume to the separation unit and further fluid driven by the fluid drive and flowing from the fluid drive to the separation unit are combined at a fluidic connection upstream of the separation unit. A control unit controls a pressure of the fluid and/or the further fluid during injecting.Type: GrantFiled: December 30, 2021Date of Patent: December 5, 2023Assignee: Agilent Technologies, Inc.Inventors: Daniel Thielsch, Thomas Ortmann, Sam Wouters
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Patent number: 11773999Abstract: A fluid valve for a sample separation apparatus includes a first valve component and a second valve component, which are adjacent to one another and movable relative to one another. The valve components are configured such that, in at least one switching state, at least one switchable fluid channel is formed between the valve components, and at least one part of a surface of at least one of the first valve component and the second valve component is provided with a coating containing gold and/or platinum.Type: GrantFiled: January 23, 2018Date of Patent: October 3, 2023Assignee: Agilent Technologies, Inc.Inventors: Tony Ziegler, Darijo Zeko, Thomas Ortmann
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Publication number: 20230296571Abstract: A valve may be utilized in a high-performance chromatography system for separating components of a sample liquid introduced into a mobile phase. The valve has a first valve element and a second valve element. By a movement of one valve element relative to the other, a first effective surface of the first valve element is brought into connection with a second effective surface of the second valve element, and a flow path may be produced or suppressed. The second valve element has an elastic region to compensate for an axial angle between the first valve element and the second valve element, such that the first effective surface and the second effective surface may be oriented parallel to each other. This may favorably influence a fluidic leak tightness and/or longevity of the valve.Type: ApplicationFiled: July 29, 2021Publication date: September 21, 2023Inventors: Thomas Ortmann, Blasius Nocon, Armin Steinke, Christian Daniel Ruf
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Publication number: 20230210420Abstract: A sampling unit includes a needle for aspirating a sample fluid, a housing, and a fitting. The needle includes a needle tip and a needle channel through the needle for guiding the aspirated sample fluid. The needle channel opens at the needle tip. The housing includes a housing cavity and a housing channel opening into the housing cavity. The fitting includes a fitting cavity and a fitting channel. The fitting is configured for sealingly receiving the needle tip into the fitting cavity and for being inserted into the housing cavity, so that the fitting channel on one side fluidically couples to the needle channel and on another side couples to the housing channel.Type: ApplicationFiled: June 22, 2021Publication date: July 6, 2023Inventors: Thomas Ortmann, Michael Lang
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Patent number: 11630090Abstract: A sample dispatcher for a fluid separation apparatus includes a sampling path including a sampling volume, a sampling unit, and a retaining unit. The sampling unit receives a fluidic sample, and the sampling volume temporarily stores an amount of the received sample. The retaining unit receives and retains from the sampling volume at least a portion of the stored sample, and has different retention characteristics for different components of the sample. A switching unit is coupled to the sampling path, a sampling fluid drive, a mobile phase drive, and a separating device. In a feed injection configuration of the switching unit, the mobile phase drive, the separating device, and the sampling path are coupled together in a coupling point for combining a flow from the sampling fluid drive containing the fluidic sample retained by the retaining unit with a flow of the mobile phase from the mobile phase drive.Type: GrantFiled: July 30, 2020Date of Patent: April 18, 2023Assignee: Agilent Technologies, Inc.Inventors: Thomas Ortmann, Thomas Glauner