Patents by Inventor Thomas P. Dooley

Thomas P. Dooley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20020035611
    Abstract: A system and method for providing an information network on the Internet is provided. The system includes a plurality of websites and at least one redirect assigned to each website. The websites each include a category, information about the category and a domain name that corresponds to the category. The redirect includes a URL redirect that directs a browser or a server to the assigned website. The method includes the steps of: (1) providing a plurality of websites; (2) providing each website with a category, information about the category, and a domain name that corresponds to the category; (3) providing at least one redirect assigned to each website; and (4) providing each redirect with a URL redirect that directs at least one of a browser and a server to the assigned website.
    Type: Application
    Filed: December 28, 2000
    Publication date: March 21, 2002
    Inventor: Thomas P. Dooley
  • Publication number: 20010046671
    Abstract: The present invention is directed to methods for making and using informative nucleic acid arrays (e.g., DNA including cDNA, RNA, PNA) for research and other applications in various disciplines or areas of interest. Examples of such disciplines include, without limitation, dermatology, pharmacology, toxicology, oncology, gynecology, urology, gastroenterology, as well as studies of sentinel gene discovery, signature gene discovery, mechanism of action, drug screening, drug metabolism, etc. The informative nucleic acid arrays of the present invention may contain only the gene sequences that are of interest in a particular area of interest or application, and may exclude other gene sequences.
    Type: Application
    Filed: January 16, 2001
    Publication date: November 29, 2001
    Inventors: Thomas P. Dooley, Ernest V. Curto, Richard L. Davis
  • Patent number: 6229001
    Abstract: The invention relates to the nucleic acid sequence and amino acid sequence of dihydrofolate reductase (DHFR) from mycobacteria and to expression of recombinant DHFR protein. Utilizing the recombinant protein, novel therapies and diagnostic strategies can be developed and selective antimycobacterial compositions can be designed and utilized to treat mycobacterial infections in patients. This invention includes all or portions of novel recombinant nucleic acids encoding DHFR for mycobacteria such as M. avium, to novel recombinant DHFR peptides produced by such sequences, and to vaccines, diagnostic kits, cells and therapies utilizing these peptides and nucleic acid sequences. The present invention relates to methods for using the sequences of the present invention to develop drugs specific to M. avium and other mycobacteria, to identify and sequence corresponding sequences in species other than M. avium, as well as diagnostic and treatment methods incorporating the disclosed sequences and peptides.
    Type: Grant
    Filed: December 15, 1997
    Date of Patent: May 8, 2001
    Assignee: Southern Research Institute
    Inventors: William W. Barrow, Sabrina Z. Van Ginkel, Thomas P. Dooley, William J. Suling
  • Patent number: 5910424
    Abstract: A cell line of metastatic, pigmented, malignant melanoma cells made by exposing a litter of Monodelphis domestica suckling young to an accumulated dose of ultraviolet radiation and then continuing the ultraviolet exposure after the young are weaned to induce malignant melanoma tumors and culturing the tumor cells from lymph nodes. This cell line can be used to test anti-cancer agents in vitro. Further this cell line can be injected into Monodelphis domestica suckling young so that tumors develop in the animals, and the anti-cancer agents can be tested in vivo.
    Type: Grant
    Filed: December 3, 1997
    Date of Patent: June 8, 1999
    Assignee: Southwest Foundation for Biomedical Research
    Inventors: Thomas P. Dooley, Edward S. Robinson
  • Patent number: 5869332
    Abstract: A cell line of metastatic, pigmented, malignant melanoma cells made by exposing a litter of Monodelphis domestica suckling young to an accumulated dose of ultraviolet radiation and then continuing the ultraviolet exposure after the young are weaned to induce malignant melanoma tumors and culturing the tumor cells from lymph nodes. This cell line can be used to test anti-cancer agents in vitro. Further this cell line can be injected into Monodelphis domestica suckling young so that tumors develop in the animals, and the anti-cancer agents can be tested in vivo.
    Type: Grant
    Filed: June 3, 1994
    Date of Patent: February 9, 1999
    Assignee: Southwest Foundation for Biomedical Research
    Inventors: Thomas P. Dooley, Edward S. Robinson
  • Patent number: 5424192
    Abstract: This invention is directed to the identification, isolation and use of nonprostate derived markers, such as markers derived from the seminal vesicles, and antibodies which recognize these markers in the diagnosis of invasive proatic neoplasia, to diagnostic aids for screening biological samples for evidence of invasive prostatic neoplasia, and to methods for the use of these diagnostic aids.
    Type: Grant
    Filed: March 29, 1993
    Date of Patent: June 13, 1995
    Assignee: Baylor College of Medicine
    Inventors: Timothy C. Thompson, Thomas P. Dooley