Patents by Inventor Thomas P. Jerussi

Thomas P. Jerussi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DERIVATIVES OF (-)-VENLAFAXINE AND METHODS OF PREPARING AND USING THE SAME
    Publication number: 20150299102
    Abstract: Methods of preparing, and compositions comprising, derivatives of (?)-venlafaxine are disclosed. Also disclosed are methods of treating and preventing diseases and disorders including, but not limited to, affective disorders such as depression, bipolar and manic disorders, attention deficit disorder, attention deficit disorder with hyperactivity, Parkinson's disease, epilepsy, cerebral function disorders, obesity and weight gain, incontinence, dementia and related disorders.
    Type: Application
    Filed: July 1, 2015
    Publication date: October 22, 2015
    Inventors: Thomas P. Jerussi, Chrisantha H. Senanayake, Nandkumar N. Bhongle
  • Methods of using derivatives of (?)-venlafaxine
    Patent number: 9072700
    Abstract: Methods of preparing, and compositions comprising, derivatives of (?)-venlafaxine are disclosed. Also disclosed are methods of treating and preventing diseases and disorders including, but not limited to, affective disorders such as depression, bipolar and manic disorders, attention deficit disorder, attention deficit disorder with hyperactivity, Parkinson's disease, epilepsy, cerebral function disorders, obesity and weight gain, incontinence, dementia and related disorders.
    Type: Grant
    Filed: December 23, 2013
    Date of Patent: July 7, 2015
    Assignee: Sunovion Pharmaceuticals Inc.
    Inventors: Thomas P. Jerussi, Chrisantha H. Senanayake, Nandkumar N. Bhongle
  • METHODS OF USING DERIVATIVES OF (-)-VENLAFAXINE
    Publication number: 20140121283
    Abstract: Methods of preparing, and compositions comprising, derivatives of (?)-venlafaxine are disclosed. Also disclosed are methods of treating and preventing diseases and disorders including, but not limited to, affective disorders such as depression, bipolar and manic disorders, attention deficit disorder, attention deficit disorder with hyperactivity, Parkinson's disease, epilepsy, cerebral function disorders, obesity and weight gain, incontinence, dementia and related disorders.
    Type: Application
    Filed: December 23, 2013
    Publication date: May 1, 2014
    Applicant: Sunovion Pharmaceuticals Inc.
    Inventors: Thomas P. JERUSSI, Chrisantha H. SENANAYAKE, Nandkumar N. BHONGLE
  • Methods of using derivatives of (?)-venlafaxine
    Patent number: 8642662
    Abstract: Methods of preparing, and compositions comprising, derivatives of (?)-venlafaxine are disclosed. Also disclosed are methods of treating and preventing diseases and disorders including, but not limited to, affective disorders such as depression, bipolar and manic disorders, attention deficit disorder, attention deficit disorder with hyperactivity, Parkinson's disease, epilepsy, cerebral function disorders, obesity and weight gain, incontinence, dementia and related disorders.
    Type: Grant
    Filed: May 25, 2012
    Date of Patent: February 4, 2014
    Assignee: Sunovion Pharmaceuticals Inc.
    Inventors: Thomas P. Jerussi, Chrisantha H. Senanayake, Nandkumar N. Bhongle
  • Derivatives of venlafaxine and methods of preparing and using the same
    Publication number: 20120302794
    Abstract: Methods of preparing, and compositions comprising, derivatives of venlafaxine are disclosed. Also disclosed are methods of treating and preventing diseases and disorders including, but not limited to, affective disorders such as depression, bipolar and manic disorders, attention deficit disorder, attention deficit disorder with hyperactivity, Parkinson's disease, epilepsy, cerebral function disorders, obesity and weight gain, incontinence, dementia and related disorders.
    Type: Application
    Filed: August 9, 2012
    Publication date: November 29, 2012
    Inventors: Thomas P. Jerussi, Chrisantha H. Senanayake, Nandkumar N. Bhongle
  • Derivatives of venlafaxine and methods of preparing and using the same
    Patent number: 8269040
    Abstract: Methods of preparing, and compositions comprising, derivatives of venlafaxine are disclosed. Also disclosed are methods of treating and preventing diseases and disorders including, but not limited to, affective disorders such as depression, bipolar and manic disorders, attention deficit disorder, attention deficit disorder with hyperactivity, Parkinson's disease, epilepsy, cerebral function disorders, obesity and weight gain, incontinence, dementia and related disorders.
    Type: Grant
    Filed: November 25, 2003
    Date of Patent: September 18, 2012
    Assignee: Wyeth LLC
    Inventors: Thomas P. Jerussi, Chrisantha H. Senanayake, Nandkumar N. Bhongle
  • METHODS OF USING DERIVATIVES OF (-)-VENLAFAXINE
    Publication number: 20120232157
    Abstract: Methods of preparing, and compositions comprising, derivatives of (?)-venlafaxine are disclosed. Also disclosed are methods of treating and preventing diseases and disorders including, but not limited to, affective disorders such as depression, bipolar and manic disorders, attention deficit disorder, attention deficit disorder with hyperactivity, Parkinson's disease, epilepsy, cerebral function disorders, obesity and weight gain, incontinence, dementia and related disorders.
    Type: Application
    Filed: May 25, 2012
    Publication date: September 13, 2012
    Inventors: Thomas P. Jerussi, Chrisantha H. Senanayake, Nandkumar N. Bhongle
  • Treatment of CNS Disorders with trans 4-(3,4-Dichlorophenyl)-1,2,3,4-Tetrahydro-1-Napthalenamine
    Publication number: 20120136065
    Abstract: Treatment of CNS disorders with (1R,4S)-trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine; and (1S,4R)-trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine is disclosed. A process for preparing 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine is also disclosed. The process includes the preparation of all four isomers of N-[4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydronaphthalen-1-yl]formamide, which are also useful.
    Type: Application
    Filed: February 3, 2012
    Publication date: May 31, 2012
    Applicant: SUNOVION PHARMACEUTICALS INC.
    Inventors: Thomas P. JERUSSI, Qun Kevin FANG, Mark G. CURRIE
  • Treatment of CNS Disorders With trans 4-(3,4-Dichlorophenyl)-1,2,3,4-Tetrahydro-1-Napthalenamine
    Publication number: 20100292340
    Abstract: Treatment of CNS disorders with (1R,4S)-trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine; and (1S,4R)-trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine is disclosed. A process for preparing 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine is also disclosed. The process includes the preparation of all four isomers of N-[4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydronaphthalen-1-yl]formamide, which are also useful.
    Type: Application
    Filed: July 30, 2010
    Publication date: November 18, 2010
    Applicant: SEPRACOR INC.
    Inventors: Thomas P. JERUSSI, Qun Kevin FANG, Mark G. CURRIE
  • Imidazo[1,2-A]pyridine anxiolytics
    Patent number: 7723324
    Abstract: Imidazo[1,2-a]pyridines of the formulae I and II: are disclosed. The compounds are useful to treat anxiety and insomnia. Pharmaceutical compositions and methods are also disclosed.
    Type: Grant
    Filed: October 28, 2004
    Date of Patent: May 25, 2010
    Assignee: Sepracor, Inc.
    Inventors: Q. Kevin Fang, Paul Grover, Thomas P. Jerussi
  • Treatment of CNS Disorders With trans 4-(3,4-Dichlorophenyl)-1,2,3,4-Tetrahydro-1-Napthalenamine
    Publication number: 20090292026
    Abstract: Treatment of CNS disorders with (1R,4S)-trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine; and (1S,4R)-trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine is disclosed. A process for preparing 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine is also disclosed. The process includes the preparation of all four isomers of N-[4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydronaphthalen-1-yl]formamide, which are also useful.
    Type: Application
    Filed: August 10, 2009
    Publication date: November 26, 2009
    Applicant: Sepracor Inc.
    Inventors: Thomas P. Jerussi, Qun Kevin Fang, Mark G. Currie
  • Imidazo[1,2-A] pyridine anxiolytics
    Patent number: 7566725
    Abstract: Imidazo[1,2-a]pyridines of the formulae I and II: are disclosed. The compounds are useful to treat anxiety and insomnia. Pharmaceutical compositions and methods are also disclosed.
    Type: Grant
    Filed: September 15, 2006
    Date of Patent: July 28, 2009
    Assignee: Sepracor Inc.
    Inventors: Q. Kevin Fang, Paul Grover, Thomas P. Jerussi
  • Compositions comprising zopiclone derivatives and methods of making and using the same
    Patent number: 7456173
    Abstract: The invention is directed to racemic and stereomerically pure compounds of Formula 3: and to pharmaceutical compositions comprising them, methods of their use, and methods of their preparation.
    Type: Grant
    Filed: October 26, 2006
    Date of Patent: November 25, 2008
    Assignee: Sepracor Inc.
    Inventors: Thomas P. Jerussi, Qun K. Fang
  • Treatment of CNS Disorders With trans 4-(3,4-Dichlorophenyl)-1,2,3,4-Tetrahydro-1-Napthalenamine
    Publication number: 20080280993
    Abstract: Treatment of CNS disorders with (1R,4S)-trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine; and (1S,4R)-trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine is disclosed. A process for preparing 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine is also disclosed. The process includes the preparation of all four isomers of N-[4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydronaphthalen-1-yl]formamide, which are also useful.
    Type: Application
    Filed: July 15, 2008
    Publication date: November 13, 2008
    Applicant: SEPRACOR INC.
    Inventors: Thomas P. Jerussi, Qun Kevin Fang, Mark G. Currie
  • Dosage forms of O-desmethylvenlafaxine
    Publication number: 20080132578
    Abstract: Methods of preparing, and compositions comprising, derivatives of venlafaxine are disclosed. Also disclosed are methods of treating and preventing diseases and disorders including, but not limited to, affective disorders such as depression, bipolar and manic disorders, attention deficit disorder, attention deficit disorder with hyperactivity, Parkinson's disease, epilepsy, cerebral function disorders, obesity and weight gain, incontinence, dementia and related disorders.
    Type: Application
    Filed: January 23, 2008
    Publication date: June 5, 2008
    Inventors: Thomas P. Jerussi, Chrisantha H. Senanayake, Nandkumar N. Bhongle
  • Imidazo[1,2-A] Pyridine Anxiolytics
    Publication number: 20080096867
    Abstract: Imidazo[1,2-a]pyridines of the formulae I and II: are disclosed. The compounds are useful to treat anxiety and insomnia. Pharmaceutical compositions and methods are also disclosed.
    Type: Application
    Filed: October 28, 2004
    Publication date: April 24, 2008
    Applicant: Sepracor inc.
    Inventors: Q. Kevin Fang, Paul Grover, Thomas P. Jerussi
  • Compositions comprising zopiclone derivatives and methods of making and using the same
    Patent number: 7189715
    Abstract: The invention is directed to racemic and stereomerically pure compounds of Formula 3: and to pharmaceutical compositions comprising them, methods of their use, and methods of their preparation.
    Type: Grant
    Filed: October 24, 2003
    Date of Patent: March 13, 2007
    Assignee: Sepracor Inc.
    Inventors: Thomas P. Jerussi, Qun K. Fang
  • Imidazo[1,2-a] pyridine anxiolytics
    Patent number: 7148353
    Abstract: Imidazo[1,2-a]pyridines of the formulae I and II: are disclosed. The compounds are useful to treat anxiety and insomnia. Pharmaceutical compositions and methods are also disclosed.
    Type: Grant
    Filed: October 28, 2004
    Date of Patent: December 12, 2006
    Assignee: Sepracor Inc.
    Inventors: Kevin Fang, Paul Grover, Thomas P. Jerussi
  • Treatment of CNS disorders with trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine and its formamide
    Patent number: 7105699
    Abstract: Treatment of CNS disorders with (1R,4S)-trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine; and (1S,4R)-trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine is disclosed. A process for preparing 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine is also disclosed. The process includes the preparation of all four isomers of N-[4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydronaphthalen-1-yl]formamide, which are also useful.
    Type: Grant
    Filed: September 7, 2005
    Date of Patent: September 12, 2006
    Assignee: Sepracor Inc.
    Inventors: Thomas P. Jerussi, Qun Kevin Fang, Mark G. Currie
  • Treatment of CNS disorders with trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine and its formamide
    Patent number: 7087785
    Abstract: Treatment of CNS disorders with (1R,4S)-trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine; and (1S,4R)-trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine is disclosed. A process for preparing 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine is also disclosed. The process includes the preparation of all four isomers of N-[4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydronaphthalen-1-yl]formamide, which are also useful.
    Type: Grant
    Filed: September 16, 2003
    Date of Patent: August 8, 2006
    Assignee: Sepracor Inc.
    Inventors: Thomas P. Jerussi, Qun Kevin Fang, Mark G. Currie