Patents by Inventor Thomas P. Mathews

Thomas P. Mathews has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9908849
    Abstract: Imidamide (amidine) analogs that can inhibit the activity of sphingosine kinase 1 and sphingosine kinase 2 (SphK1 & SphK2) are provided. The compounds can prevent angiogenesis in tumors.
    Type: Grant
    Filed: August 19, 2016
    Date of Patent: March 6, 2018
    Assignee: University of Virginia Patent Foundation
    Inventors: Kevin R. Lynch, Timothy L. Macdonald, Thomas P. Mathews, Andrew Kennedy, Yugesh Kharel
  • Publication number: 20170166525
    Abstract: Imidamide (amidine) analogs that can inhibit the activity of sphingosine kinase 1 and sphingosine kinase 2 (SphK1 & SphK2) are provided. The compounds can prevent angiogenesis in tumors.
    Type: Application
    Filed: August 19, 2016
    Publication date: June 15, 2017
    Inventors: Kevin R. Lynch, Timothy L. Macdonald, Thomas P. Mathews, Andrew Kennedy, Yugesh Kharel
  • Patent number: 9421177
    Abstract: Imidamide (amidine) analogs that can inhibit the activity of sphingosine kinase 1 and sphingosine kinase 2 (SphK1 & SphK2) are provided. The compounds can prevent angiogenesis in tumors.
    Type: Grant
    Filed: August 16, 2010
    Date of Patent: August 23, 2016
    Assignee: University of Virginia Patent Foundation
    Inventors: Kevin R. Lynch, Timothy L. Macdonald, Thomas P. Mathews, Andrew Kennedy, Yugesh Kharel
  • Patent number: 8686046
    Abstract: Amidine analogs that can inhibit the activity of sphingosine kinase 1 and sphingosine kinase 2 (SphK1 & SphK2) are provided. The compounds can prevent angiogenesis in tumor cells.
    Type: Grant
    Filed: October 2, 2010
    Date of Patent: April 1, 2014
    Assignee: University of Virginia Patent Foundation
    Inventors: Kevin R. Lynch, Timothy L. Macdonald, Yugesh Kharel, Thomas P. Mathews, Brian R. Wamhoff
  • Publication number: 20120214858
    Abstract: Imidamide (amidine) analogs that can inhibit the activity of sphingosine kinase 1 and sphingosine kinase 2 (SphK1 & SphK2) are provided. The compounds can prevent angiogenesis in tumors.
    Type: Application
    Filed: August 16, 2010
    Publication date: August 23, 2012
    Applicant: University of Virginia Patent Foundation
    Inventors: Kevin R. Lynch, Timothy L. Macdonald, Thomas P. Mathews, Andrew Kennedy, Yugesh Kharel
  • Publication number: 20110106241
    Abstract: Amidine analogs that can inhibit the activity of sphingosine kinase 1 and sphingosine kinase 2 (SphK1 & SphK2) are provided. The compounds can prevent angiogenesis in tumor cells.
    Type: Application
    Filed: October 2, 2010
    Publication date: May 5, 2011
    Inventors: Kevin R. Lynch, Timothy L. Macdonald, Yugesh Kharel, Thomas P. Mathews, Brian R. Wamhoff
  • Patent number: 7124463
    Abstract: A street sweeper system is used typically in a motorized vehicle. The sweeper utilizes a cylindrical brush rotating about an axis that is typically perpendicular to the vehicle's direction of motion. A conveyor belt catches debris thrown forwards and upward by the brush and moves the debris to a hopper. A conveyor lip is mounted on a lower edge of the conveyor to improve sweeping performance. The conveyor lip covers a space between the lower edge of the conveyor and the ground. The lip's lower edge is angled towards the brush to deflect debris back towards the brush to recirculate the debris.
    Type: Grant
    Filed: September 6, 2002
    Date of Patent: October 24, 2006
    Assignee: Tennant Company
    Inventors: Thomas P. Mathews, Michael H. Lenzmeier, Archie A. Weidner, Gregory J. Engel
  • Publication number: 20040045583
    Abstract: A street sweeper system is used typically in a motorized vehicle. The sweeper utilizes a cylindrical brush rotating about an axis that is typically perpendicular to the vehicle's direction of motion. A conveyor belt catches debris thrown forwards and upward by the brush and moves the debris to a hopper. A conveyor lip is mounted on a lower edge of the conveyor to improve sweeping performance. The conveyor lip covers a space between the lower edge of the conveyor and the ground. The lip's lower edge is angled towards the brush to deflect debris back towards the brush to recirculate the debris.
    Type: Application
    Filed: September 6, 2002
    Publication date: March 11, 2004
    Applicant: Tennant
    Inventors: Thomas P. Mathews, Michael H. Lenzmeier, Archie A. Weidner, Gregory J. Engel
  • Publication number: 20040045584
    Abstract: A street sweeper system is used in a motorized vehicle. The sweeper utilizes a cylindrical brush rotating about a horizontal axis that is typically perpendicular to the vehicle's direction of motion. A conveyor belt catches debris thrown forwards and upward by the brush and moves the debris to a hopper. A conveyor flap is mounted on a lower edge of the conveyor to improve sweeping performance. The conveyor lip covers a space between the lower edge of the conveyor and the ground. A cutoff flap is located on a forward portion of the brush to deflect debris that is passing over the brush. A recirculation flap is located at a rear portion of the brush to recirculate debris that has passed over the top of the brush.
    Type: Application
    Filed: September 6, 2002
    Publication date: March 11, 2004
    Applicant: Tennant
    Inventors: Thomas P. Mathews, Michael H. Lenzmeier, Archie A. Weidner, Michael S. Wilmo, Gregory J. Engel
  • Patent number: 5996174
    Abstract: A vacuum trash collection vehicle includes a debris container and a source of vacuum, both mounted on the vehicle. There is a hose connected at one end to the debris container and the source of vacuum is applied thereto. The opposite end of the hose is open to form a collection nozzle. A boom supports the hose during use as a debris collection device. There is a driver accessible control for moving the hose and nozzle which includes an elongated tubular assembly, pivotally mounted at its upper end to the boom and movably mounted at its lower end to the collection nozzle. There is an operator's handle, having multiple hand-gripping areas, mounted on the tubular assembly and movable relative thereto during use of the debris collection hose.
    Type: Grant
    Filed: June 15, 1998
    Date of Patent: December 7, 1999
    Assignee: Tennant Company
    Inventors: Steven L. Boomgaarden, Thomas P. Mathews
  • Patent number: 5069136
    Abstract: A two-stage release self-righting mechanism and method employ a pair of primary and secondary releasable holder assemblies which respective hold upper and middle portions of leaf spring arms in a stowed position against the side wall of a load such as a submunition launcher tube. The primary holder assembly is released first which permits release of a portion of the energy stored by the spring legs, causing them to partially extend from the stowed position to a partially deployed position and partially erect the submunition. Then, a short time later, the secondary holder assembly is released, permitting release of the remaining energy stored by the spring legs, causing them to fully extend to a fully deployed position and complete the erecting of the submunition.
    Type: Grant
    Filed: September 14, 1990
    Date of Patent: December 3, 1991
    Assignee: Honeywell Inc.
    Inventors: Eric T. Axelson, Thomas P. Mathews