Patents by Inventor Thomas P. White

Thomas P. White has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11137310
    Abstract: GaN/Al0.20Ga0.80N/GaN heterostructures Micro-Hall effect sensors providing simultaneous current and temperature detection over at least a best performance temperature range of ?183° C. and 252° C.
    Type: Grant
    Filed: October 16, 2018
    Date of Patent: October 5, 2021
    Inventors: Thomas P. White, Satish Shetty, Morgan E. Ware, H. Alan Mantooth, Gregory J. Salamo
  • Publication number: 20190120712
    Abstract: GaN/Al0.20Ga0.80N/GaN heterostructures Micro-Hall effect sensors providing simultaneous current and temperature detection over at least a best performance temperature range of ?183° C. and 252° C.
    Type: Application
    Filed: October 16, 2018
    Publication date: April 25, 2019
    Inventors: Thomas P. White, Satish Shetty, Morgan E. Ware, H. Alan Mantooth, Gregory J. Salamo
  • Patent number: 9302225
    Abstract: A method and apparatus to trap, release and/or separate sample components in solution passing through a channel with or without packing material present by passing ion current through the channel driven by an electric field. A portion of the ion current includes cation and/or anion species generated from second solution flows separated from the sample solution flow path by semipermeable membranes. Cation and/or anion species generated in the second solution flow regions are transferred into the sample solution flow path through ion selective semipermeable membranes. Ion current moving along the sample solution flow path is controlled by varying the composition of the second solutions and/or changing the voltage between membrane sections for a given sample solution composition. The sample composition may also be varied separately or in parallel to enhance trapping, release and/or separation efficiency and range.
    Type: Grant
    Filed: July 15, 2013
    Date of Patent: April 5, 2016
    Assignee: PerkinElmer Health Sciences, Inc.
    Inventors: Craig M. Whitehouse, Thomas P. White
  • Patent number: 9299553
    Abstract: A multiple function atmospheric pressure ion source interfaced to a mass spectrometer comprises multiple liquid inlet probes configured such that the sprays from two or more probes intersect in a mixing region. Gas phase sample ions or neutral species generated in the spray of one probe can react with reagent gas ions generated from one or more other probes by such ionization methods as Electrospray, photoionization, corona discharge and glow discharge ionization. Reagent ions may be optimally selected to promote such processes as Atmospheric Pressure Chemical Ionization of neutral sample molecules, or charge reduction or electron transfer dissociation of multiply charged sample ions. Selected neutral reagent species can also be introduced into the mixing region to promote charge reduction of multiply charged sample ions through ion-neutral reactions. Different operating modes can be performed alternately or simultaneously, and can be rapidly turned on and off under manual or software control.
    Type: Grant
    Filed: March 26, 2014
    Date of Patent: March 29, 2016
    Assignees: PerkinElmer Health Sciences, Inc., Chem-Space Associates, Inc.
    Inventors: Craig M. Whitehouse, Thomas P. White, Ross C. Willoughby, Edward William Sheehan
  • Publication number: 20140326871
    Abstract: A multiple function atmospheric pressure ion source interfaced to a mass spectrometer comprises multiple liquid inlet probes configured such that the sprays from two or more probes intersect in a mixing region Gas phase sample ions or neutral species generated in the spray of one probe can react with reagent gas ions generated from one or more other probes by such ionization methods as Electrospray, photoionization, corona discharge and glow discharge ionization. Reagent ions may be optimally selected to promote such processes as Atmospheric Pressure Chemical Ionization of neutral sample molecules, or charge reduction or electron transfer dissociation of multiply charged sample ions.
    Type: Application
    Filed: March 26, 2014
    Publication date: November 6, 2014
    Applicants: Chem-Space Associates, Inc., PerkinElmer Health Sciences, Inc.
    Inventors: Craig M. Whitehouse, Thomas P. White, Ross C. Willoughby, Edward William Sheehan
  • Patent number: 8723110
    Abstract: An apparatus for generating ions includes an Electrospray ionization source configured to provide a spray of charged droplets from a sample solution during operation of the apparatus; an atmospheric pressure chemical ionization (APCI) source including a corona discharge needle configured to produce a corona discharge that further ionizes the spray during operation of the apparatus; and a gas delivery system configured to deliver a gas flow to the corona discharge needle during operation of the apparatus, wherein the gas flow comprises a reagent ion gas which facilitates ionization of the spray by the corona discharge.
    Type: Grant
    Filed: August 26, 2011
    Date of Patent: May 13, 2014
    Assignees: PerkinElmer Health Sciences, Inc., Chem-Space Associates, Inc.
    Inventors: Craig M. Whitehouse, Thomas P. White, Ross C. Willoughby, Edward William Sheehan
  • Publication number: 20140048700
    Abstract: A method and apparatus to trap, release and/or separate sample components in solution passing through a channel with or without packing material present by passing ion current through the channel driven by an electric field. A portion of the ion current includes cation and/or anion species generated from second solution flows separated from the sample solution flow path by semipermeable membranes. Cation and/or anion species generated in the second solution flow regions are transferred into the sample solution flow path through ion selective semipermeable membranes. Ion current moving along the sample solution flow path is controlled by varying the composition of the second solutions and/or changing the voltage between membrane sections for a given sample solution composition. The sample composition may also be varied separately or in parallel to enhance trapping, release and/or separation efficiency and range.
    Type: Application
    Filed: July 15, 2013
    Publication date: February 20, 2014
    Inventors: Craig M. Whitehouse, Thomas P. White
  • Patent number: 8525105
    Abstract: Electrospray ionization sources interfaced to mass spectrometers have become widely used tools in analytical applications Processes occurring in Electrospray (ES) ionization generally include the addition or removal of a charged species such as II+ or other cation to effect ionization of a sample species. Electrospray includes ionization processes that occur in the liquid and gas phase and in both phases ionization processes require a source or sink for such charged species. Electrolyte species, that aid in oxidation or reduction reactions occurring in Electrospray ionization, are added to sample solutions in many analytical applications to increase the ES ion signal amplitude detected by a mass spectrometer (MS). Electrolyte species that may be required to enhance an upstream sample preparation or separation process may be less compatible with the downstream ES processes and cause reduction in MS signal.
    Type: Grant
    Filed: September 10, 2010
    Date of Patent: September 3, 2013
    Assignee: PerkinElmer Health Sciences, Inc.
    Inventors: Craig M. Whitehouse, Thomas P. White
  • Patent number: 8487243
    Abstract: The invention provides a method and apparatus for trapping, releasing and/or separating sample components in solution passing through a channel with or without packing material present by passing ion current through the channel driven by an electric field. A portion of the ion current comprises cation and/or anion species generated from second solution flows separated from the sample solution flow path by semipermeable membranes. Cation and/or Anion ion species generated in the second solution flow regions are transferred into the sample solution flow path through ion selective semipermeable membranes. Ion current moving along the sample solution flow path is controlled by varying the composition of the second solutions and/or changing the voltage between membrane sections for a given sample solution composition. The sample composition may also be varied separately or in parallel to enhance trapping, release and/or separation efficiency and range.
    Type: Grant
    Filed: January 14, 2011
    Date of Patent: July 16, 2013
    Assignee: PerkinElmer Health Sciences, Inc.
    Inventors: Craig M. Whitehouse, Thomas P. White
  • Publication number: 20110006198
    Abstract: Electrospray ionization sources interfaced to mass spectrometers have become widely used tools in analytical applications Processes occurring in Electrospray (ES) ionization generally include the addition or removal of a charged species such as II+ or other cation to effect ionization of a sample species. Electrospray includes ionization processes that occur in the liquid and gas phase and in both phases ionization processes require a source or sink for such charged species. Electrolyte species, that aid in oxidation or reduction reactions occurring in Electrospray ionization, are added to sample solutions in many analytical applications to increase the ES ion signal amplitude detected by a mass spectrometer (MS). Electrolyte species that may be required to enhance an upstream sample preparation or separation process may be less compatible with the downstream ES processes and cause reduction in MS signal.
    Type: Application
    Filed: September 10, 2010
    Publication date: January 13, 2011
    Inventors: Craig M. Whitehouse, Thomas P. White
  • Patent number: 7800057
    Abstract: Electrospray ionization sources interfaced to mass spectrometers have become widely used tools in analytical applications. Processes occurring in Electrospray (ES) ionization generally include the addition or removal of a charged species such as H+ or other cation to effect ionization of a sample species. Electrospray includes ionization processes that occur in the liquid and gas phase and in both phases ionization processes require a source or sink for such charged species. Electrolyte species, that aid in oxidation or reduction reactions occurring in Electrospray ionization, are added to sample solutions in many analytical applications to increase the ES ion signal amplitude detected by a mass spectrometer (MS). Electrolyte species that may be required to enhance an upstream sample preparation or separation process may be less compatible with the downstream ES processes and cause reduction in MS signal.
    Type: Grant
    Filed: June 2, 2008
    Date of Patent: September 21, 2010
    Assignee: PerkinElmer Health Sciences, Inc.
    Inventors: Craig M. Whitehouse, Thomas P. White
  • Publication number: 20090008547
    Abstract: Electrospray ionization sources interfaced to mass spectrometers have become widely used tools in analytical applications. Processes occurring in Electrospray (ES) ionization generally include the addition or removal of a charged species such as H+ or other cation to effect ionization of a sample species. Electrospray includes ionization processes that occur in the liquid and gas phase and in both phases ionization processes require a source or sink for such charged species. Electrolyte species, that aid in oxidation or reduction reactions occurring in Electrospray ionization, are added to sample solutions in many analytical applications to increase the ES ion signal amplitude detected by a mass spectrometer (MS). Electrolyte species that may be required to enhance an upstream sample preparation or separation process may be less compatible with the downstream ES processes and cause reduction in MS signal.
    Type: Application
    Filed: June 2, 2008
    Publication date: January 8, 2009
    Inventors: Craig M. Whitehouse, Thomas P. White
  • Publication number: 20080103720
    Abstract: The present invention provides a managed or “hosted” service offering that facilitates timely and accurate communication of clinical information, such as critical test results, within a health care environment. The inventive system enables pathologists, laboratory technicians, and laboratory staff to communicate to ordering physicians clinical information (such as lab results) in real-time via a traceable and verifiable communication system. According to the invention, a recipient of the clinical test results is prompted to verify the test results that he or she has just heard to confirm receipt of such results, as well as confirmation that the information provided was properly understood. The read back function ensures that the actual communication of complete clinical information (such as critical tests results) occurs in a seamless, real-time manner.
    Type: Application
    Filed: October 25, 2006
    Publication date: May 1, 2008
    Inventors: Peter M. White, Thomas P. White
  • Patent number: 6670607
    Abstract: The present invention relates to a nanospray emitter including an emitter body which includes a fluid inlet, an outlet orifice, and a passage communicating between the fluid inlet and outlet orifice; and an electrically conductive polymer coating on at least a portion of the emitter body. Also disclosed are a nano-electrospray device including the nanospray emitter of the present invention, a method for making a nanospray emitter of the present invention, a method of forming a nanospray using the nanospray emitter of the present invention, and a method of analyzing a solution using the nanospray emitter of the present invention.
    Type: Grant
    Filed: January 4, 2001
    Date of Patent: December 30, 2003
    Assignee: The Research Foundation of State University of New York
    Inventors: Troy D. Wood, E. Peter Maziarz, III, Sarah A. Lorenz, Thomas P. White
  • Publication number: 20020003209
    Abstract: The present invention relates to a nanospray emitter including an emitter body which includes a fluid inlet, an outlet orifice, and a passage communicating between the fluid inlet and outlet orifice; and an electrically conductive polymer coating on at least a portion of the emitter body. Also disclosed are a nano-electrospray device including the nanospray emitter of the present invention, a method for making a nanospray emitter of the present invention, a method of forming a nanospray using the nanospray emitter of the present invention, and a method of analyzing a solution using the nanospray emitter of the present invention.
    Type: Application
    Filed: January 4, 2001
    Publication date: January 10, 2002
    Inventors: Troy D. Wood, E. Peter Maziarz, Sarah A. Lorenz, Thomas P. White
  • Patent number: 4286348
    Abstract: A conventional shoe last is provided with an adapter assembly to facilitate lasting of boots and/or other ankle-covering malleoli circumventing footwear. The assembly includes an upward extension that has medially, laterally adjustable medial and lateral portions, each preferably with an adjustable cup-forming member, and each with a skirt for filling in around the thinner top backpart of the conventional shoe last. The V-notch of the conventional shoe last is provided with an adjustable cone portion that at least partially covers the cone portion of the shoe last in order to provide the close fit needed for active wear boots.
    Type: Grant
    Filed: September 5, 1979
    Date of Patent: September 1, 1981
    Inventor: Thomas P. White, Sr.
  • Patent number: 4153253
    Abstract: A puck for playing an ice hockey-like game, on untraditional surfaces, is provided with a generally cylindrical body of foam rubber or the like. Two smaller-diameter disks or end plates of glide material are secured coaxially therewith on respective opposite ends of the body. The disks and main body are attached to each other by adhesive bonding; maybe a provision is made within the main body and between the end disks to receive weights. An aperture is provided for installing selected amount of material internally of the body weighting after the disks and main body have been secured together.
    Type: Grant
    Filed: January 11, 1978
    Date of Patent: May 8, 1979
    Inventor: Thomas P. White, Sr.
  • Patent number: RE44887
    Abstract: The invention provides a method and apparatus for trapping, releasing and/or separating sample components in solution passing through a channel with or without packing material present by passing ion current through the channel driven by an electric field. A portion of the ion current comprises cation and/or anion species generated from second solution flows separated from the sample solution flow path by semipermeable membranes. Cation and/or Anion ion species generated in the second solution flow regions are transferred into the sample solution flow path through ion selective semipermeable membranes. Ion current moving along the sample solution flow path is controlled by varying the composition of the second solutions and/or changing the voltage between membrane sections for a given sample solution composition. The sample composition may also be varied separately or in parallel to enhance trapping, release and/or separation efficiency and range.
    Type: Grant
    Filed: March 23, 2011
    Date of Patent: May 13, 2014
    Assignee: PerkinElmer Health Sciences, Inc.
    Inventors: Craig M. Whitehouse, Thomas P. White