Abstract: The present application provides pharmaceutical formulations comprising PEGylated FGF?21, e.g., a FGF-21 conjugate, and one or more stabilizers such as the chelator DPTA. The formulations can be can further stabilized by including a surfactant such as polysorbate 80 and/or adjusting the pH to about 7.1. Also provided are methods of manufacture, methods of treatment, and kits.

Abstract: The present application provides pharmaceutical formulations comprising PEGylated FGF-21, e.g., a FGF-21 conjugate, and one or more stabilizers such as the chelator DPTA. The formulations can be can further stabilized by including a surfactant such as polysorbate 80 and/or adjusting the pH to about 7.1. Also provided are methods of manufacture, methods of treatment, and kits.

Abstract: The present application provides pharmaceutical formulations comprising a FGF-21 polypeptide, e.g., a modified FGF-21 polypeptide such as PEG-FGF-21, and one or more stabilizers such as the chelator DPTA. The formulations can be can further stabilized by including a surfactant such as polysorbate 80 and/or adjusting the pH to about 7.1. Also provided are methods of manufacture, methods of treatment, and kits.

Abstract: A solvent extraction apparatus comprises a cooler for condensing solvent vapor and a funnel provided towards its lower end. The funnel has an upper surface at which terminates a central downwards directed elongate outlet having an internal exit port formed in a side wall. A vertically movable lifting rod passes through the cooler and the outlet. A section of the lifting rod is shaped to delimit a passage-way for condensate while simultaneously sealing the port. A liquid guide is provided at the upper surface to preferentially direct flow of condensate towards the passage-way.

Abstract: A single use filtering device comprises a filter body formed at least in part of a filter medium configured to hold a sample during filtration and a fastening element configured for releasably mounting the filtering device to a holder. The fastening element being adapted to undergo an irreversible structural alteration during the mounting or removal of the filtering device from the holder to prevent remounting of the filtering device to the holder.

Abstract: A solvent extraction apparatus comprises a cooler for condensing solvent vapour and a funnel provided towards its lower end. The funnel has an upper surface at which terminates a central downwards directed elongate outlet having an internal exit port formed in a side wall. A vertically movable lifting rod passes through the cooler and the outlet. A section of the lifting rod is shaped to delimit a passage-way for condensate whilst simultaneously sealing the port. A liquid guide is provided at the upper surface to preferentially direct flow of condensate towards the passage-way.

Abstract: The invention relates to a wood substrate rendered flame-retardant. The invention provides that on the substrate there is a coating and/or impregnation system with a flame retardant selected from the group consisting of room-temperature-liquid organic halogen compounds and organic phosphorus compounds and organic boron compounds, and that there is also a layer of coating material applied thereto.

Abstract: A high speed servo laner apparatus and system includes an entrance to the laner which receives products from an upstream processing line. A pivoting guide has a distal end attached to the entrance and a proximal end attached to a movable portion. At least one pacing screw is also attached to the moveable portion. The at least one pacing screw includes a thread, which has a pitch and radius configured to accommodate passage of a unit of product between two axially adjacent portions of the thread.

Abstract: A method of operating a portable ultrasound device to display digital video information from a video camera includes loading instructions into a memory of the device that configures processor electronics to process digital video signals. When a request for the video is received, the ultrasound device can ready itself to receive digital video information and display an image at a display of the ultrasound device based at least in part on the video information. In one embodiment, the video modality is enabled when the portable ultrasound device detects that the digital camera device has been connected to a port.

Abstract: The invention relates to a wood substrate rendered flame-retardant. The invention provides that on the substrate there is a coating and/or impregnation system with a flame retardant selected from the group consisting of room-temperature-liquid organic halogen compounds and organic phosphorus compounds and organic boron compounds, and that there is also a layer of coating material applied thereto.

Abstract: A high speed servo laner apparatus and system includes an entrance to the laner which receives products from an upstream processing line. A pivoting guide has a distal end attached to the entrance and a proximal end attached to a movable portion. At least one pacing screw is also attached to the moveable portion. The at least one pacing screw includes a thread, which has a pitch and radius configured to accommodate passage of a unit of product between two axially adjacent portions of the thread.

Abstract: An application issues an application command to a file system of the computing device, where the application command includes a location of data at a source. The file system allocates space on a medium for the data and compiles a list including an identification of each portion of the medium that is to be used to store the data. The file system then issues a file system command to a block driver of the medium, where the file system command includes the location of the data at the source and the compiled list. The block driver contacts the source, requests the data at the location thereof, and writes the data to the portions of the medium included in the compiled list.

Abstract: The present invention relates to a solvent-borne two-component (2K) coating composition comprising: as a first component, a dispersion comprising: a hydroxyl-functional acrylate binder; a first solvent being at least one compound selected from the group consisting of 2-propoxyethanol and 2-butoxyethanol; water in an amount from 5 to 50 wt. % by weight of the composition; and, optionally at least one further organic solvent; and, as a second component, at least one crosslinking agent. More particularly, the present invention provides a solvent-borne two-component (2K) polyurethane coating composition, wherein said second component comprises at least one crosslinking agent having isocyanate groups.

Abstract: A single use filtering device comprises a filter body formed at least in part of a filter medium configured to hold a sample during filtration and a fastening element configured for releasably mounting the filtering device to a holder. The fastening element being adapted to undergo an irreversible structural alteration during the mounting or removal of the filtering device from the holder to prevent remounting of the filtering device to the holder.

Abstract: An application issues an application command to a file system of the computing device, where the application command includes a location of data at a source. The file system allocates space on a medium for the data and compiles a list including an identification of each portion of the medium that is to be used to store the data. The file system then issues a file system command to a block driver of the medium, where the file system command includes the location of the data at the source and the compiled list. The block driver contacts the source, requests the data at the location thereof, and writes the data to the portions of the medium included in the compiled list.

Abstract: An application issues an application command to a file system of the computing device, where the application command includes a location of data at a source. The file system allocates space on a medium for the data and compiles a list including an identification of each portion of the medium that is to be used to store the data. The file system then issues a file system command to a block driver of the medium, where the file system command includes the location of the data at the source and the compiled list. The block driver contacts the source, requests the data at the location thereof, and writes the data to the portions of the medium included in the compiled list.

Abstract: A logic circuit having at least a first input terminal and at least a first output terminal, comprises at least a first and a second electron-wave Y-branch switch, each having a source, a first drain, a second drain, and at least a first gate for switching a source current between the first and the second drain. The sources of said first and second Y-branch switches are adapted to be connected to a high voltage supply and a low voltage supply, respectively. The first gates of said first and second Y-branch switches are interconnected, and the interconnection point between said first gates constitutes said first input terminal. The first drain of the first Y-branch switch is connected to the second drain of the second Y-branch switch, and the second drain of the first Y-branch switch is connected to the first drain of the second Y-branch switch.