Patents by Inventor Thomas Palmieri

Thomas Palmieri has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8215821
    Abstract: A test vessel agitator assembly that agitates test vessels and the contents therein within an immunoassay automated analyzer system. The test vessels are transported along an element that is comprised of ridges and troughs such that the test vessel is moved in a directions that is approximately perpendicular to the direction of transportation.
    Type: Grant
    Filed: December 15, 2006
    Date of Patent: July 10, 2012
    Assignee: Siemens Healthcare Diagnostics Inc.
    Inventors: Arthur L. Babson, Thomas Palmieri
  • Patent number: 7951329
    Abstract: A rotary luminometer subsystem presents test vessels to a detection mechanism to be read as part of the automated immunoassay analyzer system. The rotary luminometer provides a read station separate from that of the transportation element of the luminometer. Within the read station, a housing and shield eliminates light leakage from the sample under test. In addition, the read station regulates the intensity of the light by providing an attenuation capability.
    Type: Grant
    Filed: March 31, 2004
    Date of Patent: May 31, 2011
    Assignee: Siemens Healthcare Diagnostics Inc.
    Inventors: Ilya Malyarov, Thomas Palmieri
  • Publication number: 20070097783
    Abstract: A test vessel agitator assembly that agitates test vessels and the contents therein within an immunoassay automated analyzer system. The test vessels are transported along an element that is comprised of ridges and troughs such that the test vessel is moved in a directions that is approximately perpendicular to the direction of transportation.
    Type: Application
    Filed: December 15, 2006
    Publication date: May 3, 2007
    Inventors: Arthur Babson, Thomas Palmieri
  • Patent number: 7175334
    Abstract: A test vessel agitator assembly that agitates test vessels and the contents therein within an immunoassay automated analyzer system. The test vessels are transported along an element that is comprised of ridges and troughs such that the test vessel is moved in a directions that is approximately perpendicular to the direction of transportation.
    Type: Grant
    Filed: March 31, 2004
    Date of Patent: February 13, 2007
    Assignee: DPC Cirrus, Inc.
    Inventors: Arthur L. Babson, Thomas Palmieri
  • Publication number: 20050220669
    Abstract: A rotary luminometer subsystem presents test vessels to a detection mechanism to be read as part of the automated immunoassay analyzer system. The rotary luminometer provides a read station separate from that of the transportation element of the luminometer. Within the read station, a housing and shield eliminates light leakage from the sample under test. In addition, the read station regulates the intensity of the light by providing an attenuation capability.
    Type: Application
    Filed: March 31, 2004
    Publication date: October 6, 2005
    Inventors: Ilya Malyarov, Thomas Palmieri
  • Publication number: 20050219944
    Abstract: A test vessel agitator assembly that agitates test vessels and the contents therein within an immunoassay automated analyzer system. The test vessels are transported along an element that is comprised of ridges and troughs such that the test vessel is moved in a directions that is approximately perpendicular to the direction of transportation.
    Type: Application
    Filed: March 31, 2004
    Publication date: October 6, 2005
    Inventors: Arthur Babson, Thomas Palmieri
  • Publication number: 20050220670
    Abstract: A multipath incubator that enables an immunoassay analyzer to perform tests that are not conducted serially relative to when the test samples entered the analyzer is provided.
    Type: Application
    Filed: March 31, 2004
    Publication date: October 6, 2005
    Inventors: Thomas Palmieri, Arthur Babson, Ilya Malyarov, David Stein
  • Patent number: 5885529
    Abstract: An improved automated immunoassay analyzer including a high throughput automated immunoassay system which can perform high volume testing on a broad range of analytes while selecting from among a diverse set of immunoassays for any given sample. The immunoanalyzer has the capacity to perform a wide range of different types of immunoassays by facile storage and automated combination aboard the instrument among a wide variety of different types of reagents and heterogenous immunoassay beads stored on-board the instrument. The automated design allows reduced user interface (e.g., tests are performed automatically from computer input) including the ability to order, perform and reassay tests reflexively based on test results without operator intervention. Further, the inventive analyzer is not sample tube specific; that is, an instrument that can accept sample tube sizes within a broad size range.
    Type: Grant
    Filed: June 28, 1996
    Date of Patent: March 23, 1999
    Assignee: DPC Cirrus, Inc.
    Inventors: Arthur L. Babson, Thomas Palmieri, Anthony P. Montalbano, Chris P. Montalbano, Greg A. Montalbano, Eric C. Fleischer
  • Patent number: 5885530
    Abstract: An improved automated immunoassay analyzer including a high throughput automated immunoassay system which can perform high volume testing on a broad range of analytes while selecting from among a diverse set of immunoassays for any given sample. The immunoanalyzer has the capacity to perform a wide range of different types of immunoassays by facile storage and automated combination aboard the instrument among a wide variety of different types of reagents and heterogenous immunoassay beads stored on-board the instrument. The automated design allows reduced user interface (e.g., tests are performed automatically from computer input) including the ability to order, perform and reassay tests reflexively based on test results without operator intervention. Further, the inventive analyzer is not sample tube specific; that is, an instrument that can accept sample tube sizes within a broad size range.
    Type: Grant
    Filed: July 10, 1998
    Date of Patent: March 23, 1999
    Assignee: DPC Cirrus, Inc.
    Inventors: Arthur L. Babson, Thomas Palmieri, Anthony P. Montalbano, Chris P. Montalbano, Greg A. Montalbano, Eric C. Fleischer
  • Patent number: 5721141
    Abstract: A tube washing system including a tube spinning station having a rotatable chuck and a waste chamber surrounding the chuck for capturing and draining tube fluids expelled from a spun tube driven in rotation by the chuck. The chuck has a body portion and a plurality of spaced apart teeth defining intervening grooves extending through the body portion with at least one of the grooves permitting passage of fluid through the body portion and at least one other of the grooves receives and mechanically connects a projection on an open end of a tube. A pipette for dispensing wash water into a tube is located centrally within the chuck. There is also a tube elevating device located beneath the tube spinning station, the tube elevating device comprising a freely rotatable tube holder, and lift drive motor provided to vertically move the tube holder towards and way from the chuck. The tube used in the washing system has at least one projection provided on its open end which can interlock with a chuck groove.
    Type: Grant
    Filed: June 28, 1996
    Date of Patent: February 24, 1998
    Assignee: DPC Cirrus Inc.
    Inventors: Arthur L. Babson, Thomas Palmieri
  • Patent number: 5632399
    Abstract: Self-sealing reagent container, and a system of same on a carousel, related to a vessel having a plurality of separate compartments, each compartment having an opening in an upper surface of the vessel, with a hinged lid member attached to said vessel having spring-like biasing to automatically reseal openings of the vessel after reagent extraction. The lid has a first arm that is normally biased such that its caps cover the compartment openings, but external force can be applied to said first arm to permit the first arm to be translated so as to displace the caps from covering the compartment openings whereby reagent in the compartments can be accessed and withdrawn. Once the reagent extraction is completed and the compartment opening cleared of the extraction device, the normal biasing acting on the first arm of the lid causes it to move back to reseal the caps over the compartment openings.
    Type: Grant
    Filed: June 28, 1996
    Date of Patent: May 27, 1997
    Assignee: DPC Cirrus Inc.
    Inventors: Thomas Palmieri, Arthur L. Babson
  • Patent number: 5468453
    Abstract: An improved pipette probe in an automated chemical analysis system is provided, along with a pipette tip wash protocol to reduce carryover. The pipette tip comprises an elongated stainless-steel barrel which houses a polytetrafluoroethylene tube. The non-wettable properties of polytetrafluoroethylene inhibit fluid adhesion and thereby reduce carryover. The pipette tip is swaged at a fluid dispensing end to a restrictive diameter for good pipetting precision and accuracy. A novel wash protocol is also provided which includes a novel wash solution comprising quantities of Triton X-100 nonionic detergent, Diethanolamine, and NaCl.
    Type: Grant
    Filed: June 14, 1993
    Date of Patent: November 21, 1995
    Assignee: Cirrus Diagnostics, Inc.
    Inventors: Robert W. Holt, Thomas Palmieri
  • Patent number: 5244635
    Abstract: A centrifuge vessel for performing immunoassays, affinity chromatography, and like experiments includes a center tube and an outer waste chamber. A biomaterial is held within the center tube and is capable of binding specific analytes in test samples. In operation the centrifuge vessel is rotated at high speed about its longitudinal axis, thereby causing all fluid within the center tube to be transported into the outer waste chamber while the analyte of interest remains bound to the biomaterial positioned within the center tube In the centrifuge vessel, a cap connected to the outer waste chamber and extending over the center tube includes structure for preventing waste fluid expelled to the waste chamber from re-entering the center tube. In a first embodiment, the cap is either constructed from or the inside surface is coated with a hydrophobic material which repels fluids back into the waste chamber.
    Type: Grant
    Filed: June 19, 1992
    Date of Patent: September 14, 1993
    Assignee: Cirrus Diagnostics, Inc.
    Inventors: Arthur L. Rabson, Thomas Palmieri, Douglas R. Olson
  • Patent number: 5149501
    Abstract: An instrument (50) automatically determines the concentrations of HDL cholesterol, LDL cholesterol, total cholesterol and triglycerides for a sample (80) of whole, anticoagulated blood placed in a doughnut shaped container (10). The sample (80) is first separated into its blood cell and plasma (84) constituents using high speed centrifugation (54) and a thixotropic gel (82). Part of the plasma (84) is then deposited in an HDL separation chamber (14) where LDL cholesterol and VLDL cholesterol are precipitated by a reagent and the precipitant is sedimented by high speed centrifugation (54) against V-shaped grooves (40) in the outermost wall (38) of the HDL separation chamber (14). Part of the plasma (84) is diluted ten-fold. The supernatant in the HDL separation chamber is then placed in a cuvette reaction chamber (b 18) where it reacts with a cholesterol reagent. The diluted plasma is placed in two other cuvette reaction chambers (18) where it reacts with chloesterol and triglycerides reagents, respectively.
    Type: Grant
    Filed: January 29, 1990
    Date of Patent: September 22, 1992
    Assignee: Cirrus Diagnostics, Inc.
    Inventors: Arthur L. Babson, Thomas Palmieri, Douglas R. Olson
  • Patent number: 5029583
    Abstract: An optical analyzer for determining an analyte in a fluid of interest such as a body fluid of interest satisfying the foregoing need and embodying the present invention may include a housing; combination optically transparent cuvette and lancet mounted removably in the housing, the cuvette may receive an optically transparent reagent test system for reacting with the body fluid to produce a change in at least one optical transmissive characteristic of the system indicative of the analyte; a cuvette carrier mounted slidably in the housing and for removably receiving the cuvette; a spring actuator mounted in the housing and connected to the cuvette carrier, the spring actuator may be compressed and released to advance the carrier and thereby advance the lancet into engagement with a portion of a body to produce the body fluid; depth control apparatus for controlling the depth of penetration of the lancet into the body portion; an electrooptical system mounted in the housing in optical engagement with the cuvett
    Type: Grant
    Filed: November 6, 1989
    Date of Patent: July 9, 1991
    Assignee: Personal Diagnostics, Inc.
    Inventors: Peter M. Meserol, Thomas Palmieri
  • Patent number: 4902629
    Abstract: Apparatus for and process of facilitating reaction between analyte contained in a sample and test reagent system at least one of which sample and test reagent system is a liquid, wherein the liquid one of the sample and test reagent system is placed in a reservoir, the other of the analyte and test reagent system is placed in capillary means dimensioned for entry into the reservoir, the reservoir and capillary means being mounted for at least relative movement towards each other and entry of the capillary means into the reservoir to draw by capillary attraction the liquid one of the sample and test reagent system from the reservoir into the capillary means and to bring the analyte and test reagent system into contact in the capillary means and facilitate the reaction.
    Type: Grant
    Filed: October 6, 1987
    Date of Patent: February 20, 1990
    Assignee: Personal Diagnostics, Inc.
    Inventors: Peter M. Meserol, Philip Bernstein, Rita C. Prodell, Thomas Palmieri
  • Patent number: 4873993
    Abstract: Cuvette with or without a lancet secured thereto and extending therefrom for producing skin puncture to produce body fluid of interest, the cuvette is made of optically transparent material and is provided with a shape and a plurality of optical elements such as integrally formed optical elements for causing a light beam to pass therethrough by total internal reflectance and for causing the beam of light to be reflected back along a line different from the direction of the line of entry of the beam of light into the cuvette such as back along a line generally parallel to the line of entry of the beam of light into the cuvette and in the opposite direction to the direction of entry of the beam of light into the cuvette.
    Type: Grant
    Filed: July 13, 1987
    Date of Patent: October 17, 1989
    Assignee: Personal Diagnostics, Inc.
    Inventors: Peter M. Meserol, Thomas Palmieri