Abstract: Drilling mud is flowed through a valve assembly that is set at a particular open amount, measurements are taken of mud flowrate and a force exerted by the drilling mud onto a portion of the valve assembly, and density of the drilling mud is estimated based on historical data. The historical data is generated by directing multiple flows through the valve assembly, where the flows are at different flowrates, and at each flowrate different drilling muds having different densities are directed through the valve assembly. For each flow the valve assembly is adjusted to different open amounts, and a corresponding force exerted by the flow onto the valve assembly is measured. An example of the valve assembly is a mud pulser with a plug member that engages an orifice opening, a sensor in the pulser measures force exerted by the flow of mud.

Abstract: A method for calibrating a 3D printer includes the steps of providing information obtained in a factory calibration indicating a center of an inner diameter of a tip orifice in a metal extrusion nozzle and a center of a tip surface for the nozzle and inductively sensing the nozzle with an eddy current sensor when secured to a print head on a gantry or robotic arm of the 3D printer to identify a sensed location of the center of the tip surface of the nozzle. The method includes determining a location of the center of the inner diameter of the tip orifice on the nozzle on the print head and utilizing the provided information to locate the center of the inner diameter of the tip orifice.

Abstract: A drug delivery device includes a housing having proximal and distal ends and a longitudinal axis extending therebetween, an injection assembly at least partially disposed within the housing at or near the proximal end, a shield slidably coupled with the housing, a drive assembly operably coupled with the injection assembly and the shield, and a cap. The injection assembly includes a needle or a cannula. The shield is positionable in an extended position in which at least a proximal end thereof extends a distance beyond the proximal end of the housing. The drive assembly is engageable to deliver a medicament via the injection assembly. The cap is removably coupled with at least one of the shield or the housing and is adapted to limit movement of the shield when coupled with the shield and/or the housing such that the drive assembly is restricted from delivering the medicament via the injection assembly.

Abstract: A digital license plate includes a display system capable of showing a license number readable by camera systems even under poor external lighting conditions. A light redistribution element is positioned near the display system and a lighting system is positioned to direct light from the light redistribution element and toward the display system. In some embodiments the lighting system includes a narrowband lighting element such as can be provided by a narrowband light source, and the display system includes an electrophoretic or LCD display.

Abstract: The invention relates to a pharmaceutical composition of 8-chloro-5-methyl-1-1-[4-(2-pyridyloxy)cyclohexyl]-4,6-dihydro-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine, a process for the preparation thereof and its use in the treatment of diseases. The pharmaceutical composition includes a tablet kernel consisting of a disintegrant, a filler, a glidant and a lubricant.

Abstract: A drug delivery device includes a housing having proximal and distal ends and a longitudinal axis extending therebetween, an injection assembly at least partially disposed within the housing including a needle or a cannula, a drive assembly operably coupled with the injection assembly, a shield slidably coupled with the housing and operably coupled with the drive assembly, and a retention mechanism. The drive assembly is engageable to deliver a medicament via the injection assembly. The shield is positionable in an extended position in which at least a proximal end extends a distance beyond the proximal end of the housing and a retracted position where the proximal end of the housing protrudes a distance beyond the proximal end of the shield. Moving the shield to the retracted position engages the drive assembly to deliver the medicament via the injection assembly.

Abstract: Compounds, compositions and method of using these compounds are disclosed for treating a disease or disorder in which it is desirable to inhibit BAX, such as a cardiovascular disease or disorder.

Abstract: A nuclear radiation detector is disclosed. The detector includes a housing including therein: a scintillator; and a multi-pixel optical sensor positioned, relative to the scintillator, to receive photons emitted by the scintillator in response to interactions with nuclear radiation. The housing isolates the scintillator and the multi-pixel optical sensor from external light. The detector includes one or more processors operably connectable to the multi-pixel optical sensor; and one or more data stores coupled to the processors having instructions stored thereon which cause the processors to perform operations.

Abstract: The invention relates to a stable, peroxide-free pharmaceutical composition of 8-chloro-5-methyl-1-[4-(2-pyridyloxy)cyclohexyl]-4,6-dihydro-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine, and a process for the preparation thereof and its use in the treatment of diseases or conditions in which V1a inhibition plays a role or is implicated, such as autism spectrum disorder (ASD), and the core social and communication deficits of patients associated therewith. The formulation includes a compressed tablet kernel comprising: (a) compound of formula I, disintegrant, filler, glidant and lubricant; and (b) a film coating system comprising coating agent, colorant, plasticizer, anti-tacking agent, and coating vehicle. The process for making the formulation comprises combining the tablet kernel ingredients into a blend, sieving the blend, and compressing the blend to form a tablet kernel, and spraying the film coating system onto the tablet kernels.

Abstract: Data including current locations of candidate clouds to be seeded is obtained; based on same, a vehicle is caused to move proximate at least one of the candidate clouds to be seeded. Weather and cloud system data are obtained from a sensor suite associated with the vehicle, while the vehicle and sensor suite are proximate the at least one of the candidate clouds to be seeded. Vehicle position parameters are obtained from the sensor suite associated with the vehicle. Based on the weather and cloud system data and the vehicle position parameters, it is determined, via a machine learning process, which of the candidate clouds should be seeded, and, within those of the candidate clouds which should be seeded, where to disperse an appropriate seeding material. The vehicle is controlled to carry out the seeding on the candidate clouds to be seeded, in accordance with the determining step.

Abstract: Systems and techniques are provided for performing wireless communications. In some aspects, calibration of a station (STA) in a wireless communication network can be managed based on receiving a beacon frame that includes a Restricted Access Window (RAW) Parameter Set (RPS) Information Element (IE), and determining that an Association Identity (AID) indicated in the RPS IE of the received beacon frame matches a calibration AID associated with the STA. A process can further include determining a RAW based on the RPS IE and scheduling a RAW clear medium calibration (RAW-cmc) event within the RAW, based at least in part on the determination that the AID indicated in the RPS IE matches the calibration AID. Subsequently, the scheduled RAW-cmc event within the RAW can be used to perform calibration for the STA as scheduled.

Abstract: A manhole lock system includes a frame positioned over an access opening, a cover movable between a closed position in which the cover extends over the access opening, and an open position in which the access opening is exposed; and a lock mechanism for locking the cover in the closed position. The lock mechanism includes a lock member that is movable along a path between a unlocked position and a locked position, wherein in the locked position the lock member prevents the cover from moving to the open position, wherein in the unlocked position the lock member is retracted to enable movement of the cover to the open position.

Abstract: This disclosure describes a system and method for generating a subsurface model representing lithological characteristics and attributes of the subsurface of a celestial body or planet. By automatically ingesting data from many sources, a machine learning system can infer information about the characteristics of regions of the subsurface and build a model representing the subsurface rock properties. In some cases, this can provide information about a region using inferred data, where no direct measurements have been taken. Remote sensing data, such as aerial or satellite imagery, gravimetric data, magnetic field data, electromagnetic data, and other information can be readily collected or is already available at scale.

Abstract: An induction sensing method for identifying the center of a tip surface of a nozzle of print head of a 3D printer includes providing an eddy current sensor in a fixed position and providing a metal nozzle with a tip orifice in a main body and a tip surface about the tip orifice. The method includes moving the metal nozzle over the eddy current sensor in a predetermined motion path above the eddy current sensor while the eddy current sensor remains stationary and samples the magnitude of inductance in a generated inductive field, thereby generating a curve representing the inductive field. The method includes identifying a maximum amplitude of the curve to identify the center of the tip surface.

Abstract: A method for calibrating a 3D printer includes the steps of providing information obtained in a factory calibration indicating a center of an inner diameter of a tip orifice in a metal extrusion nozzle and a center of a tip surface for the nozzle and inductively sensing the nozzle with an eddy current sensor when secured to a print head on a gantry or robotic arm of the 3D printer to identify a sensed location of the center of the tip surface of the nozzle. The method includes determining a location of the center of the inner diameter of the tip orifice on the nozzle on the print head and utilizing the provided information to locate the center of the inner diameter of the tip orifice.

Abstract: A process to remove impurities from a surface of a cargo tank of a vessel used to transport liquid hydrocarbons includes using an active chemical solution to dissolve at least a portion of the impurities or the matrix in which they are embedded deposited n the surface of the cargo tank. The process also includes allowing the active chemical solution to subsequently remove embedded impurities from the surface.

Abstract: An industrial fluid additive composition comprises one or more sequestering agents one or more compounds of formula (A): (A) wherein R1 and R2 are independently selected from substituted hydrocarbyl moieties containing from 1 to 10 carbon atoms or unsubstituted hydrocarbyl moieties containing from 1 to 10 carbon atoms.

Abstract: A method for calibrating a 3D printer includes the steps of providing information obtained in a factory calibration indicating a center of an inner diameter of a tip orifice in a metal extrusion nozzle and a center of a tip surface for the nozzle and inductively sensing the nozzle with an eddy current sensor when secured to a print head on a gantry or robotic arm of the 3D printer to identify a sensed location of the center of the tip surface of the nozzle. The method includes determining a location of the center of the inner diameter of the tip orifice on the nozzle on the print head and utilizing the provided information to locate the center of the inner diameter of the tip orifice.

Abstract: The disclosed technology is generally directed to identifying media documents embedded within other media documents. In one example of the technology, source fingerprints are generated from input images using a source machine-learning model. The input images are derived from the media documents. Target fingerprints are generated from the input images using a target machine-learning model. The source machine-learning model includes a first neural network. The target machine-learning model includes a second neural network that is different from the first neural network. The source machine-learning model was trained in parallel with the target machine-learning model. Candidate media-document pairs from the media documents are determined based on the source fingerprints and the target fingerprints. Each candidate media-document pair includes a media document that is a candidate for being embedded in another media document.