Patents by Inventor Thomas Peter John Dunkley

Thomas Peter John Dunkley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • E3 UBIQUITIN LIGASE (UBE3A) PROTEIN TARGETS
    Publication number: 20220091137
    Abstract: The invention relates to UBE3A protein targets and their usage as target engagement biomarkers for compounds that modulate ube3a expression.
    Type: Application
    Filed: January 15, 2020
    Publication date: March 24, 2022
    Inventors: Veronica Costa, Thomas Peter John Dunkley, Nikhil Janak Pandya, Ravi Jagasia
  • COMPANION DIAGNOSTIC FOR HTRA1 RNA ANTAGONISTS
    Publication number: 20200378970
    Abstract: The present invention relates to the use of HTRA1 mRNA antagonists in the treatment of eye disorders, such as macular degeneration, and the use of an HTRA1 levels in the aqueous and vitreous humor as a diagnostic biomarker for the suitability of treatment of a subject with an HTRA1 mRNA antagonist.
    Type: Application
    Filed: December 19, 2018
    Publication date: December 3, 2020
    Inventors: Rubén Alvarez Sánchez, Roberto Iacone, Peter Jakob, Jean-Luc Mary, Heidi Rye Hudlebusch, Thomas Peter John Dunkley, Corinne Stucki, Ulrich Friedrich Oskar Luhmann, Carolin Rakebrandt