Patents by Inventor Thomas Petzinger, Jr.

Thomas Petzinger, Jr. has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS OF USING R(+) PRAMIPEXOLE
    Publication number: 20160022647
    Abstract: Pharmaceutical compositions of R(+) pramipexole and methods of using such compositions for the treatment or prevention of diseases associated with or related to mitochondrial dysfunction or increased oxidative stress are disclosed.
    Type: Application
    Filed: October 2, 2015
    Publication date: January 28, 2016
    Inventors: Michael E. BOZIK, Gregory T. HEBRANK, Thomas PETZINGER, JR.
  • COMPOSITIONS AND METHODS FOR TREATING CONDITIONS RELATED TO INCREASED EOSINOPHILS
    Publication number: 20150018397
    Abstract: Disclosed herein are methods of treating diseases associated with increased numbers of eosinophils basophils, and/or neutrophils with R(+) pramipexole.
    Type: Application
    Filed: August 13, 2013
    Publication date: January 15, 2015
    Inventors: Michael E. BOZIK, Gregory HEBRANK, Wildon FARWELL, Thomas Petzinger, JR., Steven Dworetzky
  • COMPOSITIONS AND METHODS FOR TREATING AMYOTROPHIC LATERAL SCLEROSIS IN RESPONDERS
    Publication number: 20140329869
    Abstract: A method for treating amyotrophic lateral sclerosis (ALS) in a subject in need thereof comprising administering to said subject an effective amount of (6R)-2-amino-4,5,6,7-tetrahydro-6-(propylamino)benzothiazole or pharmaceutically acceptable salt thereof, wherein said subject is a treatment responder. In certain embodiments, said subject is a subject with definite amyotrophic lateral sclerosis, a subject with amyotrophic lateral sclerosis symptom onset duration of less than about 18 months, a subject with a high level of serum creatinine, a subject with concomitant riluzole administration and combinations thereof.
    Type: Application
    Filed: February 28, 2014
    Publication date: November 6, 2014
    Applicant: KNOPP BIOSCIENCES, LLC
    Inventors: Michael E. BOZIK, Thomas PETZINGER, JR., James L. MATHER, Donald ARCHIBALD
  • Modified Release Formulations of (6R)-4,5,6,7-tetrahydro-N6-propyl-2,6-benzothiazole-diamine and Methods of Using the Same
    Publication number: 20140031401
    Abstract: Modified release pharmaceutical compositions (controlled release, sustained release, and/or extended release) of the R-(+) enantiomer of pramipexole (RPPX) and methods of using such compositions for the treatment of neurodegenerative diseases, or those related to mitochondrial dysfunction or increased oxidative stress are disclosed.
    Type: Application
    Filed: July 16, 2013
    Publication date: January 30, 2014
    Inventors: Michael E. BOZIK, Thomas PETZINGER, JR., Valentin GRIBKOFF
  • COMPOSITIONS AND METHODS OF USING (R)-PRAMIPEXOLE
    Publication number: 20130310430
    Abstract: Pharmaceutical compositions of (R)-pramipexole and methods and kits of using such compositions for the treatment of neurodegenerative diseases, or those related to mitochondrial dysfunction or increased oxidative stress are disclosed.
    Type: Application
    Filed: July 15, 2013
    Publication date: November 21, 2013
    Applicant: KNOPP NEUROSCIENCES, INC.
    Inventors: Michael E. BOZIK, Thomas PETZINGER, JR., Valentin GRIBKOFF
  • Modified release formulations of (6R)-4,5,6,7-tetrahydro-N6-propyl-2,6-benzothiazole-diamine and methods of using the same
    Patent number: 8524695
    Abstract: Modified release pharmaceutical compositions (controlled release, sustained release, and/or extended release) of the R-(+) enantiomer of pramipexole (RPPX) and methods of using such compositions for the treatment of neurodegenerative diseases, or those related to mitochondrial dysfunction or increased oxidative stress are disclosed.
    Type: Grant
    Filed: March 14, 2008
    Date of Patent: September 3, 2013
    Assignee: Knopp Neurosciences, Inc.
    Inventors: Michael E. Bozik, Thomas Petzinger, Jr., Valentin Gribkoff
  • Compositions and methods of using (R)-pramipexole
    Patent number: 8518926
    Abstract: Pharmaceutical compositions of (R)-pramipexole and methods and kits of using such compositions for the treatment of neurodegenerative diseases, or those related to mitochondrial dysfunction or increased oxidative stress are disclosed.
    Type: Grant
    Filed: December 14, 2007
    Date of Patent: August 27, 2013
    Assignee: Knopp Neurosciences, Inc.
    Inventors: Michael E. Bozik, Thomas Petzinger, Jr., Valentin Gribkoff
  • Compositions of R(+) and S(?) pramipexole and methods of using the same
    Patent number: 8445474
    Abstract: Compositions of predetermined amounts of R(+) pramipexole and S(?) pramipexole and methods of using the same, including for the treatment and prevention of Parkinson's disease, are provided.
    Type: Grant
    Filed: August 5, 2011
    Date of Patent: May 21, 2013
    Assignee: Knopp Neurosciences, Inc.
    Inventors: Michael E. Bozik, Thomas Petzinger, Jr., Valentin Gribkoff
  • Compositions and Methods of Using R(+) Pramipexole
    Publication number: 20120225915
    Abstract: Pharmaceutical compositions of R(+) pramipexole and methods of using such compositions for the treatment or prevention of diseases associated with or related to mitochondrial dysfunction or increased oxidative stress are disclosed.
    Type: Application
    Filed: May 9, 2012
    Publication date: September 6, 2012
    Applicant: Knopp Neurosciences Inc.
    Inventors: Michael E. Bozik, Gregory T. Hebrank, Thomas Petzinger, JR.
  • Compositions of R(+) and S(-) Pramipexole and Methods of Using the Same
    Publication number: 20110293718
    Abstract: Compositions of predetermined amounts of R(+) pramipexole and S(?) pramipexole and methods of using the same, including for the treatment and prevention of Parkinson's disease, are provided.
    Type: Application
    Filed: August 5, 2011
    Publication date: December 1, 2011
    Applicant: KNOPP NEUROSCIENCES, INC.
    Inventors: Michael E. BOZIK, Thomas PETZINGER, JR., Valentin GRIBKOFF
  • Compositions and methods of using R(+) pramipexole
    Publication number: 20110224268
    Abstract: Pharmaceutical compositions of R(+) pramipexole and methods of using such compositions for the treatment or prevention of diseases associated with or related to mitochondrial dysfunction or increased oxidative stress are disclosed.
    Type: Application
    Filed: February 28, 2011
    Publication date: September 15, 2011
    Applicant: Knopp Neurosciences Inc
    Inventors: Michael E. Bozik, Gregory T. Hebrank, Thomas Petzinger, JR.
  • Compositions of R(+) and S(?) pramipexole and methods of using the same
    Patent number: 8017598
    Abstract: Compositions of predetermined amounts of R(+) pramipexole and S(?) pramipexole and methods of using the same, including for the treatment and prevention of Parkinson's disease, are provided.
    Type: Grant
    Filed: May 16, 2007
    Date of Patent: September 13, 2011
    Assignee: Knopp Neurosciences, Inc.
    Inventors: Michael E. Bozik, Thomas Petzinger, Jr., Valentin Gribkoff
  • Modified Release Formulations of (6R)-4,5,6,7-tetrahydro-N6-propyl-2,6-benzothiazole-diamine and Methods of Using the Same
    Publication number: 20090054504
    Abstract: Modified release pharmaceutical compositions (controlled release, sustained release, and/or extended release) of the R-(+) enantiomer of pramipexole (RPPX) and methods of using such compositions for the treatment of neurodegenerative diseases, or those related to mitochondrial dysfunction or increased oxidative stress are disclosed.
    Type: Application
    Filed: March 14, 2008
    Publication date: February 26, 2009
    Applicant: KNOPP NEUROSCIENCES, INC.
    Inventors: Michael E. Bozik, Thomas Petzinger, Jr., Valentin Gribkoff
  • COMPOSITIONS AND METHODS OF USING (R)-PRAMIPEXOLE
    Publication number: 20090042956
    Abstract: Pharmaceutical compositions of (R)-pramipexole and methods and kits of using such compositions for the treatment of neurodegenerative diseases, or those related to mitochondrial dysfunction or increased oxidative stress are disclosed.
    Type: Application
    Filed: December 14, 2007
    Publication date: February 12, 2009
    Applicant: KNOPP NEUROSCIENCES, INC.
    Inventors: Michael E. Bozik, Thomas Petzinger, JR., Valentin Gribkoff