Patents by Inventor Thomas Philip Kurtzman

Thomas Philip Kurtzman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD OF USING A WATER-BASED PHARMACOPHORE
    Publication number: 20160253451
    Abstract: A method for producing a template of a binding site of a target protein is provided. A target protein is modeled in silico. A binding site is hydrated with water molecules by finding areas within the binding site where water molecules remain localized during a molecular dynamic simulation. Interactions of the water molecules with the hydration sites are classified as a hydrogen bond acceptor interaction (A) or a hydrogen bond donor interaction (D). The classified interactions are mapped to provide a template of hydrogen bond interactions with the protein.
    Type: Application
    Filed: October 7, 2014
    Publication date: September 1, 2016
    Inventors: Thomas Philip Kurtzman, Steven James Ramsey, Brian Lee Olson, Eun Sung Cho, Sangwon Jung, Minsup Kim