Patents by Inventor Thomas Philipps

Thomas Philipps has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted triols
    Patent number: 6277833
    Abstract: Substituted triols are prepared by reducing appropriately substituted carboxylic esters. The substituted triols can be used as active substances in medicaments.
    Type: Grant
    Filed: September 24, 1998
    Date of Patent: August 21, 2001
    Assignee: Bayer Aktiengesellschaft
    Inventors: Rolf Angerbauer, Peter Fey, Walter Hübsch, Thomas Philipps, Hilmar Bischoff, Hans-Peter Krause, Jörg Petersen von Gehr, Delf Schmidt
  • 7-isoindolinyl-quinolone derivatives and 7-isoindolinyl-naphthyridone derivatives
    Patent number: 6018054
    Abstract: The invention relates to intermediate compounds for preparing novel quinolone derivatives- and naphthyridone derivatives which are substituted in the 7-position by a partially hydrogenated isoindolinyl ring, to processes for their preparation and to antibacterial agents and feed additives containing them.
    Type: Grant
    Filed: November 26, 1997
    Date of Patent: January 25, 2000
    Assignee: Bayer Aktiengesellschaft
    Inventors: Thomas Philipps, Stephan Bartel, Andreas Krebs, Uwe Petersen, Thomas Schenke, Klaus-Dieter Bremm, Rainer Endermann, Karl Georg Metzger, Burkhard Mielke
  • 7-isoindolinyl-quinolone derivatives and 7-isoindolinyl-naphthyridone derivatives
    Patent number: 5739339
    Abstract: The invention relates to novel quinolone derivatives and naphthyridone derivatives which are substituted in the 7-position by a partially hydrogenated isoindolinyl ring, to processes for their preparation and to antibacterial agents and feed additives containing them.
    Type: Grant
    Filed: May 17, 1996
    Date of Patent: April 14, 1998
    Assignee: Bayer Aktiengesellschaft
    Inventors: Thomas Philipps, Stephan Bartel, Andreas Krebs, Uwe Petersen, Thomas Schenke, Klaus-Dieter Bremm, Rainer Endermann, Karl Georg Metzger, Burkhard Mielke
  • 7-isoindolinyl-naphthyridone derivatives, compositions and anti-bacterial use thereof
    Patent number: 5556979
    Abstract: The invention relates to novel quinolone derivatives and naphthyridone derivatives which are substituted in the 7-position by a partially hydrogenated isoindolinyl ring, to processes for their preparation and to antibacterial agents and feed additives containing them.
    Type: Grant
    Filed: September 10, 1993
    Date of Patent: September 17, 1996
    Assignee: Bayer Aktiengesellschaft
    Inventors: Thomas Philipps, Stephan Bartel, Andreas Krebs, Uwe Petersen, Thomas Schenke, Klaus-Dieter Bremm, Rainer Endermann, Karl G. Metzger, Burkhard Mielke
  • Pyrido[1,2,3-D,E] [1,3,4]benzoxadiazine derivatives
    Patent number: 5508278
    Abstract: Novel bactericidal pyrido[1,2,3-d,e,][1,3,4]benzoxadiazine derivatives of the formula (I) ##STR1## in which R.sup.1 is hydrogen or C.sub.1 -C.sub.4 -alkyl optionally substituted by hydroxyl or halogen,R.sup.2 independently of R.sup.1 is hydrogen or methyl,R.sup.3 is hydrogen or C.sub.1 -C.sub.4 -alkyl,R.sup.4 is hydrogen, C.sub.1 -C.sub.4 -alkyl optionally substituted by hydroxyl, methoxy, amino, methylamino or dimethylamino, or (5-methyl-2-oxo-1,3-dioxol-4-yl)-methyl,X.sup.
    Type: Grant
    Filed: August 26, 1994
    Date of Patent: April 16, 1996
    Assignee: Bayer Aktiengesellschaft
    Inventors: Thomas Jaetsch, Burkhard Mielke, Uwe Petersen, Thomas Philipps, Thomas Schenke, Klaus D. Bremm, Rainer Endermann, Karl G. Metzger, Martin Scheer, Michael Stegemann, Heinz-Georg Wetzstein
  • Polysubstituted pyridines useful for treating lipoproteinanaemia and arteriosclerosis
    Patent number: 5502057
    Abstract: For the treatment of lipoproteinaemia and arteriosclerosis, the new disubstituted pyridines of the formula ##STR1## in which R.sup.1 is optionally substituted aryl or heteroaryl,R.sup.2 is cycloalkyl or optionally substituted alkyl,R.sup.3 is hydrogen, cycloalkyl, or optionally substituted alkyl, aryl or heteroaryl,x is --CH.sub.2 --CH.sub.2 -- or --CH.dbd.CH--,A is ##STR2## R.sup.6 is hydrogen or alkyl, and R.sup.7 is hydrogen, alkyl, aralkyl or a cation.
    Type: Grant
    Filed: July 14, 1993
    Date of Patent: March 26, 1996
    Assignee: Bayer Aktiengesellschaft
    Inventors: Rolf Angerbauer, Peter Fey, Walter Hu/ bsch, Thomas Philipps, Hilmar Bischoff, Dieter Petzinna, Delf Schmidt, Gu/ nter Thomas
  • Quinolonecarboxylic acids
    Patent number: 5480879
    Abstract: The invention relates to novel derivatives of quinolonecarboxylic acid and naphthyridonecarboxylic acid which are linked to a .beta.-lactam antibiotic, to their salts, to processes for their preparation and to antibacterial agents containing these derivatives.
    Type: Grant
    Filed: October 1, 1993
    Date of Patent: January 2, 1996
    Assignee: Bayer Aktiengesellschaft
    Inventors: Uwe Petersen, Wilfried Schrock, Dieter Habich, Andreas Krebs, Thomas Schenke, Thomas Philipps, Klaus Grohe, Rainer Endermann, Klaus-Dieter Bremm, Karl-Georg Metzger
  • Disubstituted pyridines
    Patent number: 5470982
    Abstract: For the treatment of lipoproteinaemia and arteriosclerosis, the new disubstituted pyridines of the formula ##STR1## in which R.sup.1 is optionally substituted aryl or heteroaryl,R.sup.2 is cycloalkyl or optionally substituted alkyl,R.sup.3 is hydrogen, cycloalkyl, or optionally substituted alkyl, aryl or heteroaryl,X is --CH.sub.2 --CH.sub.2 -- or --CH.dbd.CH--,A is ##STR2## R.sup.6 is hydrogen or alkyl, and R.sup.7 is hydrogen, alkyl, aralkyl or a cation.
    Type: Grant
    Filed: September 24, 1992
    Date of Patent: November 28, 1995
    Assignee: Bayer Aktiengesellschaft
    Inventors: Rolf Angerbauer, Peter Fey, Walter Hubsch, Thomas Philipps, Hilmar Bischoff, Dieter Petzinna, Delf Schmidt, Gunter Thomas
  • 7-isoindolinyl-quinolone-carboxylic acid derivatives
    Patent number: 5464796
    Abstract: The invention relates to new quinolone- and naphthyridonecarboxylic acid derivatives which are substituted in the 7-position by a partly hydrogenated isoindolinyl ring, processes for their preparation and antibacterial agents and feed additives containing these compounds.
    Type: Grant
    Filed: June 11, 1992
    Date of Patent: November 7, 1995
    Assignee: Bayer Aktiengesellschaft
    Inventors: Uwe Petersen, Andreas Krebs, Thomas Schenke, Franz Kunisch, Thomas Philipps, Klaus Grohe, Klaus-Dieter Bremm, Rainer Endermann, Karl-Georg Metzger, Ingo Haller, Hans-Joachim Zeiler
  • Substituted 4-phenyl-pyridones and 4-phenyl-3-alkoxypyridines
    Patent number: 5418243
    Abstract: Substituted 4-phenyl-pyridones and 4-phenyl-2-alkoxypyridines are prepared by reducing corresponding 4-phenyl-pyridone and 4-phenyl-2-alkoxypyridine derivatives. The substituted 4-phenyl-pyridones and 4-phenyl-2-alkoxypyridines can be employed as active compounds in medicaments, in particular for the treatment of hyperlipoproteinaemia.
    Type: Grant
    Filed: December 14, 1993
    Date of Patent: May 23, 1995
    Assignee: Bayer Aktiengesellschaft
    Inventors: Rolf Angerbauer, Peter Fey, Walter Hubsch, Thomas Philipps, Hilmar Bischoff, Hans-Peter Krause, Jorg Peterson-von Gehr, Delf Schmidt
  • Substituted pyridines
    Patent number: 5409910
    Abstract: New substituted pyridines are prepared by reducing suitably substituted pyridine derivatives. The new substituted pyridines are suitable as active compounds in pharmaceuticals, in particular for the treatment of hyperlipoproteinaemia.
    Type: Grant
    Filed: December 17, 1993
    Date of Patent: April 25, 1995
    Assignee: Bayer Aktiengesellschaft
    Inventors: Rolf Angerbauer, Peter Fey, Walter Hubsch, Thomas Philipps, Hilmar Bischoff, Hans-Peter Krause, Jorg P. von Gehr, Delf Schmidt
  • Substituted pyridines heptenoic acid derivatives, useful for treating arterioscleros, lipopotaemia and the like
    Patent number: 5401746
    Abstract: Novel compounds for treating hyperproteinaemia, lipoproteinaemia or arteriosclerosis of the formula ##STR1## in which A, B, D and E can have varied meanings,X is --CH.sub.2 --CH.sub.2 or --CH.dbd.CH--, andR is ##STR2## wherein R.sup.21 --denotes hydrogen or alkyl andR.sup.22 --denotes hydrogen,denotes alkyl, aryl or aralkyl, ordenotes a cation,and their oxidation products.
    Type: Grant
    Filed: July 20, 1992
    Date of Patent: March 28, 1995
    Assignee: Bayer Aktiengesellschaft
    Inventors: Rolf Angerbauer, Peter Fey, Walter Hubsch, Thomas Philipps, Hilmar Bischoff, Dieter Petzinna, Delf Schmidt, Gunter Thomas
  • Certain intermediate imino-substituted pyridines
    Patent number: 5183897
    Abstract: Intermediate imino-substituted pyridines of the formula ##STR1## in which R.sup.1 is optionally substituted aryl,R.sup.2 is optionally substituted aryl or alkyl, OH, alkoxy, aralkoxy, or optionally substituted aryloxy,R.sup.3 is isopropyl,R.sup.4 is isopropylX is --CH.sub.2 --CH.sub.2 -- or --CH.dbd.CH--,R is ##STR2## R.sup.6 is H or alkyl, and R.sup.7 is H, alkyl, phenylalkyl, aryl or a cation, and their salts.
    Type: Grant
    Filed: April 18, 1991
    Date of Patent: February 2, 1993
    Assignee: Bayer Aktiengesellschaft
    Inventors: Rolf Angerbauer, Peter Fey, Walter Hubsch, Thomas Philipps, Hilmar Bischoff, Dieter Petzinna, Delf Schmidt
  • Substituted pyridyl-dihydroxy-heptenoic acid and its salts
    Patent number: 5177080
    Abstract: Substituted pyridyl-dihydroxy-heptenoic acid of the formula ##STR1## and its salts, if desired in an isomeric form, have a superior inhibitory action on HMG-CoA reductase and thus bring about a surprisingly good lowering of the cholesterol content in the blood.
    Type: Grant
    Filed: November 26, 1991
    Date of Patent: January 5, 1993
    Assignee: Bayer Aktiengesellschaft
    Inventors: Rolf Angerbauer, Peter Fey, Walter Hubsch, Thomas Philipps, Hilmar Bischoff, Dieter Petzinna, Delf Schmidt, Gunter Thomas
  • 7-[(2,6-dialkyl-4-furyl or thienyl-pyridyl)]-3,5-di-(dihydroxy-6-enoates) useful for treating circulatory diseases
    Patent number: 5173495
    Abstract: For the treatment of lipoproteinaemia and arteriosclerosis, the polysubstituted pridines of the formula ##STR1## in which R.sup.1 is optionally substituted furyl or thienyl,R.sup.2 is cycloalkyl or optionally substituted alkyl,R.sup.3 is hydrogen, cycloalkyl, or optionally substituted alkyl, aryl or heteroaryl,X is --CH.dbd.CH--,A is ##STR2## R.sup.6 is hydrogen or alkyl, and R.sup.7 is hydrogen, alkyl, aralkyl or a cation.
    Type: Grant
    Filed: August 8, 1990
    Date of Patent: December 22, 1992
    Assignee: Bayer Aktiengesellschaft
    Inventors: Rolf Angerbauer, Peter Fey, Walter Hubsch, Thomas Philipps, Hilmar Bischoff, Dieter Petzinna, Delf Schmidt, Gunter Thomas
  • 7-(polysubstituted pyridyl)-hept-6-endates useful for treating hyperproteinaemia, lipoproteinaemia or arteriosclerosis
    Patent number: 5169857
    Abstract: Novel compounds for treating hyperproteinaemia, lipoproteinaemia or arteriosclerosis of the formula ##STR1## in which A, B, D and E can have varied meanings,X is --CH.sub.2 --CH.sub.2 or --CH.dbd.CH--, andR is ##STR2## wherein R.sup.21 denotes hydrogen or alkyl andR.sup.22denotes hydrogen,deontes alkyl, aryl or aralkyl, ordenotes a cation,and their oxidation products.
    Type: Grant
    Filed: December 13, 1990
    Date of Patent: December 8, 1992
    Assignee: Bayer Aktiengesellschaft
    Inventors: Rolf Angerbauer, Peter Fey, Walter Hubsch, Thomas Philipps, Hilmar Bischoff, Dieter Petzinna, Delf Schmidt, Gunter Thomas
  • Substituted 2-pyridones and pyrid-2-thiones compounds
    Patent number: 5164506
    Abstract: For inhibiting HMG-CoA reductase and cholesterol synthesis, the novel 2-pyridones and pyrid-2-thiones of the formula ##STR1## in which A is optionally substituted aryl or heterocyclic,B is optionally substituted alkyl, cycloalkyl or aryl,D and E independently are optionally substituted aryl or heterocyclic, H, nitro, cyano, optionally substituted alkyl, alkenyl or imino, amino, alkoxy or acyl, or forms a ring with B,G is O or S,X is --CH.sub.2 --CH.sub.2 -- or --CH.dbd.CH--, andR represents a group of the formula ##STR2## and salts thereof.
    Type: Grant
    Filed: April 19, 1991
    Date of Patent: November 17, 1992
    Assignee: Bayer Aktiengesellschaft
    Inventors: Peter Fey, Rolf Angerbauer, Walter Hubsch, Thomas Philipps, Hilmar Bischoff, Dieter Petzinna, Delf Schmidt, Gunter Thomas
  • HMG-COA reductase-inhibiting substituted amino-pyridines
    Patent number: 5145857
    Abstract: HMG-COA reductase-inhibiting compounds of the formula ##STR1## in which X represents a group of the formula --CH.sub.2 --CH.sub.2 -- or --CH.dbd.CH--,R represents a group of the formula ##STR2## R.sup.1 represents optionally substituted aryl, R.sup.2 represents --CH.sub.2 OR.sup.8 or --X--R, andR.sup.5 represents straight-chain or branched alkyl having up to 10 carbon atoms, orand their pharmaceutically acceptable salts.
    Type: Grant
    Filed: August 15, 1990
    Date of Patent: September 8, 1992
    Assignee: Bayer Aktiengesellschaft
    Inventors: Peter Fey, Rolf Angerbauer, Walter Hubsch, Thomas Philipps, Hilmar Bischoff, Dieter Petzinna, Delf Schmidt
  • Substituted pyrido (2,3-d) pyrimidines as intermediates
    Patent number: 5145959
    Abstract: Substituted pyrido(2,3-d) pyrimidines of the formula: ##STR1## useful as intermediates for the preparation of MMG-CoA reductase inhibitors.
    Type: Grant
    Filed: June 19, 1991
    Date of Patent: September 8, 1992
    Assignee: Bayer Aktiengesellschaft
    Inventors: Walter Hubsch, Rolf Angerbauer, Peter Fey, Thomas Philipps, Hilmar Bischoff, Dieter Petzinna, Delf Schmidt, Gunter Thomas
  • Substituted biphenyls
    Patent number: 5138090
    Abstract: Substituted biphenyls can be prepared by reduction of appropriate ketones and, if appropriate, subsequent hydrolysis, cyclization, hydrogenation and separation of isomers. The substituted biphenyls can be used as active compounds in medicaments.
    Type: Grant
    Filed: February 27, 1990
    Date of Patent: August 11, 1992
    Assignee: Bayer Aktiengesellschaft
    Inventors: Peter Fey, Rolf Angerbauer, Walter Hubsch, Thomas Philipps, Hilmar Bischoff, Peter Petzinna, Delf Schmidt