Patents by Inventor Thomas Pless

Thomas Pless has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Purification system
    Patent number: 7566395
    Abstract: The present invention relates to automated chromatography systems and software for controlling such automated systems for optimising the purification of a protein from a sample. The software is adapted to monitor the signal from a detector in the system, determine two signal parameters and to control the components of the system depending on the actual values of the two signal parameters.
    Type: Grant
    Filed: December 10, 2004
    Date of Patent: July 28, 2009
    Assignee: GE Healthcare Bio-Sciences AB
    Inventors: Elsa Lundblad, Lotta Hedkvist, Henrik Sundqvist, Markus Galin, Thomas Pless, Jill Simon
  • Liquid Chromatography Method
    Publication number: 20080090995
    Abstract: The present invention relates to a method for the non-magnetic purification of cellular components from a crude cell lysate by continuous liquid chromatography, which method comprises lysis of cells in a vessel to provide a crude cell lysate; passing the crude cell lysate so obtained, without any intermediate clarification, over a chromatogra-phy column packed with a porous particulate chromatography matrix to adsorb target component(s), wherein the particle surfaces present immobilised nitrilotriacetic acid (NTA) ligands charged with metal ions; and recovering the target component(s) by elu-tion.
    Type: Application
    Filed: December 20, 2005
    Publication date: April 17, 2008
    Applicant: GE HEALTHCARE BIO-SCIENCES AB
    Inventors: Karin Andersson, Ann Bergh, Thomas Pless, Jozsef Vasi