Abstract: This invention relates to a process for removing a solute from a solution. The process comprises maintaining the solution at reflux conditions to produce a vapor which evolves from the reaction solution. At least a portion of the vapor is removed from the zone and is contacted, outside of the reaction zone, with a solid removal agent which is specific for capturing to itself that portion of the vapor which was the solute to be removed and originally present in the reaction solution. After such capture, the remaining vapor is condensed and returned to the reaction zone. In another embodiment, the solute is removed from the solution by first maintaining the solution at reflux conditions in a zone to produce a vapor which evolves from the solution. At least a portion of that vapor is removed from the zone and condensed. The resultant condensate is contacted, outside of the reaction zone, with a solid removal agent which is specific for capturing unto itself the solute from the condensate.

Abstract: Substituted bis-ethers, such as .alpha.,107 -bis-(4-aminophenoxy)-alkyls, are prepared in process which involves sequential addition of reactants, reagents or neutralizing compounds without recovery of intermediate products such as diamides and diamine acid salts. When water is used as the solvent, the process is simplified and product yields in excess of about 70% are obtained.