Patents by Inventor Thomas R. Caferro

Thomas R. Caferro has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Tricyclic quinolinone and tricyclic quinoline androgen receptor modulator compounds and methods
    Patent number: 7214690
    Abstract: Novel non-steroidal tricyclic quinolinone and tricyclic quinoline compounds and compositions that are agonists, partial agonists and/or antagonists for androgen receptors (AR), their preparation and their uses are described.
    Type: Grant
    Filed: February 22, 2002
    Date of Patent: May 8, 2007
    Assignee: Ligand Pharmaceuticals Incorporated
    Inventors: Robert I. Higuchi, Lin Zhi, Donald S. Karanewsky, Anthony W. Thompson, Thomas R. Caferro, Neelakandha S. Mani, Jyun-Hung Chen, Marquis L. Cummings, James P. Edwards, Mark E. Adams, Charlotte L. F. Deckhut
  • Androgen receptor modulator compounds and methods
    Publication number: 20030186970
    Abstract: Compounds, pharmaceutical compositions, and methods for modulating processes mediated by steroid receptors. In particular, preparation and methods of use of non-steroidal compounds and compositions that are agonists, partial agonists, and antagonists for the androgen receptor (AR) are described. Further, described are the methods of making and use of critical intermediates including a stereoselective synthetic route to intermediates for the AR modulators.
    Type: Application
    Filed: September 9, 2002
    Publication date: October 2, 2003
    Inventors: Robert Higuchi, Kristen L. Arienti, Mani Neelakandha, Barbara Pio, Lin Zhi, Penghui Chen, Thomas R. Caferro
  • Tricyclic quinolinone and tricyclic quinoline androgen receptor modulator compounds and methods
    Publication number: 20020183314
    Abstract: Novel non-steroidal tricyclic quinolinone and tricyclic quinoline compounds and compositions that are agonists, partial agonists and/or antagonists for androgen receptors (AR), their preparation and their uses are described.
    Type: Application
    Filed: February 22, 2002
    Publication date: December 5, 2002
    Applicant: Ligand Pharmaceuticals Incorporated
    Inventors: Robert I. Higuchi, Lin Zhi, Donald S. Karanewsky, Anthony W. Thompson, Thomas R. Caferro, Neelakandha S. Mani, Jyun-Hung Chen, Marquis L. Cummings, James P. Edwards, Mark E. Adams, Charlotte L.F. Deckhut
  • Androgen receptor modulator compounds and methods
    Patent number: 6462038
    Abstract: Compounds, pharmaceutical compositions, and methods for modulating processes mediated by steroid receptors. In particular, preparation and methods of use of non-steroidal compounds and compositions that are agonists, partial agonists, and antagonists for the androgen receptor (AR) are described. Further, described are the methods of making and use of critical intermediates including a stereoselective synthetic route to intermediates for the AR modulators.
    Type: Grant
    Filed: August 25, 2000
    Date of Patent: October 8, 2002
    Assignee: Ligand Pharmaceuticals, Inc.
    Inventors: Robert Higuchi, Kristen L. Arienti, Mani Neelakandha, Barbara Pio, Lin Zhi, Penghui Chen, Thomas R. Caferro