Patents by Inventor Thomas R. Coleman

Thomas R. Coleman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for identifying a reagent that modulates Myt1 activity
    Patent number: 6387642
    Abstract: The present invention provides a threonine/tyrosine kinase, Myt1, that phosphorylates the cyclin-dependent kinase, Cdc2, to provide regulation of the cell cycle at the G2/M interphase. Also included are polynucleotides encoding Myt1 polypeptide and antibodies that bind to Myt1. Methods of modulating Myt1 for preventing premature entry of the cell into mitosis or to accelerate entry into mitosis are also provided, as are methods for identifying agents that modulate Myt1.
    Type: Grant
    Filed: April 30, 2001
    Date of Patent: May 14, 2002
    Assignee: California Institute of Technology
    Inventors: Paul R. Mueller, Thomas R. Coleman, Akiko Kumagai, William G. Dunphy
  • METHOD FOR IDENTIFYING A REAGENT THAT MODULATES MYT1 ACTIVITY
    Publication number: 20020016444
    Abstract: The present invention provides a threonine/tyrosine kinase, Myt1, that phosphorylates the cyclin-dependent kinase, Cdc2, to provide regulation of the cell cycle at the G2/M interphase. Also included are polynucleotides encoding Myt1 polypeptide and antibodies that bind to Myt1. Methods of modulating Myt1 for preventing premature entry of the cell into mitosis or to accelerate entry into mitosis are also provided, as are methods for identifying agents that modulate Myt1.
    Type: Application
    Filed: April 30, 2001
    Publication date: February 7, 2002
    Applicant: California Institute of Technology, a California corporation
    Inventors: Paul R. Mueller, Thomas R. Coleman, Akiko kumagai, William G. Dunphy
  • Isolated Myt1 polypeptide
    Patent number: 6225101
    Abstract: The present invention provides a threonine/tyrosine kinase, Myt1, that phosphorylates the cyclin-dependent kinase, Cdc2, to provide regulation of the cell cycle at the G2/M interphase. Also included are polynucleotides encoding Myt1 polypeptide and antibodies that bind to Myt1. Methods of modulating Myt1 for preventing premature entry of the cell into mitosis or to accelerate entry into mitosis are also provided, as are methods for identifying agents that modulate Myt1.
    Type: Grant
    Filed: June 21, 1999
    Date of Patent: May 1, 2001
    Assignee: California Institute of Technology
    Inventors: Paul R. Mueller, Thomas R. Coleman, Akiko Kumagai, William G. Dunphy
  • DNA encoding a Myt1 polypeptide
    Patent number: 6020194
    Abstract: The present invention provides a threonine/tyrosine kinase, Myt1, that phosphorylates the cyclin-dependent kinase, Cdc2, to provide regulation of the cell cycle at the G2/M interphase. Also included are polynucleotides encoding Myt1 polypeptide and antibodies that bind to Myt1. Methods of modulating Myt1 for preventing premature entry of the cell into mitosis or to accelerate entry into mitosis are also provided, as are methods for identifying agents that modulate Myt1.
    Type: Grant
    Filed: October 1, 1997
    Date of Patent: February 1, 2000
    Assignee: California Institute of Technology
    Inventors: Paul R. Mueller, Thomas R. Coleman, Akiko Kumagai, William G. Dunphy
  • Drum debarker
    Patent number: 4226271
    Abstract: Disclosed herein is a drum type debarker for the debarking of logs and the like and there is provided a drive means for rotating the drum. The drum sits in a saddle that includes vehicle tires, and a drive mechanism is provided for rotating certain of the tires or wheels so as to rotate the drum. There is also provided a flange section on the drum that has vertically mounted tires arranged in engagement therewith for holding the drum in place.
    Type: Grant
    Filed: June 21, 1978
    Date of Patent: October 7, 1980
    Inventor: Thomas R. Coleman