Patents by Inventor Thomas R. Herrin

Thomas R. Herrin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Retroviral protease inhibiting compounds
    Patent number: 7968707
    Abstract: A compound of the formula: is disclosed as an HIV protease inhibitor. Methods and compositions for inhibiting an HIV infection are also disclosed.
    Type: Grant
    Filed: February 27, 2007
    Date of Patent: June 28, 2011
    Assignee: Abbott Laboratories
    Inventors: Hing Leung Sham, Daniel W. Norbeck, Xiaoqi Chen, David A. Betebenner, Dale J. Kempf, Thomas R. Herrin, Gondi N. Kumar, Stephen L. Condon, Arthur J. Cooper, Daniel A. Dickman, Steven M. Hannick, Lawrence Kolaczkowski, Patricia A. Oliver, Daniel J. Plata, Peter J. Stengel, Eric J. Stoner, Jieh-Heh J. Tien, Jih-Hua Liu, Ketan M. Patel
  • Retroviral protease inhibiting compounds
    Patent number: 7279582
    Abstract: A compound of the formula: is disclosed as an HIV protease inhibitor. Methods and compositions for inhibiting an HIV infection are also disclosed.
    Type: Grant
    Filed: October 25, 2002
    Date of Patent: October 9, 2007
    Assignee: Abbott Laboratories
    Inventors: Eric J. Stoner, Arthur J. Cooper, Lawrence Kolaczkowski, Ketan M. Patel, Hing Leung Sham, Daniel W. Norbeck, Xiaoqi Chen, David A. Betebenner, Thomas R. Herrin, Gondi N. Kumar, Stephen L. Condon, Daniel A. Dickman, Patricia A. Oliver, Jien-Heh J. Tien
  • Retroviral protease inhibiting compounds
    Publication number: 20030100755
    Abstract: A compound of the formula: 1
    Type: Application
    Filed: October 25, 2002
    Publication date: May 29, 2003
    Inventors: Hing Leung Sham, Daniel W. Norbeck, Xiaoqi Chen, David A. Betebenner, Dale J. Kempf, Thomas R. Herrin, Gondi N. Kumar, Stephen L. Condon, Arthur J. Cooper, Daniel A. Dickman, Steven M. Hannick, Lawrence Kolaczkowski, Patricia A. Oliver, Daniel J. Plata, Peter J. Stengel, Eric J. Stoner, Jieh-Heh J. Tien, Jih-Hua Liu, Ketan M. Patel
  • Retroviral protease inhibiting compounds
    Patent number: 6472529
    Abstract: A compound of the formula: is disclosed as an HIV protease inhibitor. Methods and compositions for inhibiting an HIV infection are also disclosed.
    Type: Grant
    Filed: April 18, 2001
    Date of Patent: October 29, 2002
    Assignee: Abbott Laboratories
    Inventors: Hing Leung Sham, Daniel W. Norbeck, Xiaoqi Chen, David A. Betebenner, Dale J. Kempf, Thomas R. Herrin, Gondi N. Kumar, Stephen L. Condon, Arthur J. Cooper, Daniel A. Dickman, Steven M. Hannick, Lawrence Kolaczkowski, Patricia A. Oliver, Daniel J. Plata, Peter J. Stengel, Eric J. Stoner, Jieh-Heh J. Tien, Jih-Hua Liu, Ketan M. Patel
  • Retroviral protease inhibiting compounds
    Publication number: 20020004503
    Abstract: A compound of the formula: 1
    Type: Application
    Filed: April 18, 2001
    Publication date: January 10, 2002
    Inventors: Hing Leung Sham, Daniel W. Norbeck, Xiaoqi Chen, David A. Betebenner, Dale J. Kempf, Thomas R. Herrin, Gondi N. Kumar, Stephen L. Condon, Arthur J. Cooper, Daniel A. Dickman, Steven M. Hannick, Lawrence Kolaczkowski, Patricia A. Oliver, Daniel J. Plata, Peter J. Stengel, Eric J. Stoner, Jieh-Heh J. Tien, Jih-Hua Liu, Ketan M. Patel
  • Retroviral protease inhibiting compounds
    Patent number: 6313296
    Abstract: A compound of the formula: is disclosed as an HIV protease inhibitor. Methods and compositions for inhibiting an HIV infection are also disclosed.
    Type: Grant
    Filed: February 23, 2000
    Date of Patent: November 6, 2001
    Assignee: Abbott Laboratories
    Inventors: Hing Leung Sham, Daniel W. Norbeck, Xiaoqi Chen, David A. Betebenner, Dale J. Kempf, Thomas R. Herrin, Gondi N. Kumar, Stephen L. Condon, Arthur J. Cooper, Daniel A. Dickman, Steven M. Hannick, Lawrence Kolaczkowski, Patricia A. Oliver, Daniel J. Plata, Peter J. Stengel, Eric J. Stoner, Jieh-Heh J. Tien, Jih-Hua Liu, Ketan M. Patel
  • Retroviral protease inhibiting compounds
    Patent number: 6284767
    Abstract: A compound of the formula: is disclosed as an HIV protease inhibitor. Methods and compositions for inhibiting an HIV infection are also disclosed.
    Type: Grant
    Filed: December 8, 1998
    Date of Patent: September 4, 2001
    Assignee: Abbott Laboratories
    Inventors: Hing Leung Sham, Daniel W. Norbeck, Dale J. Kempf, Xiaoqi Chen, David A. Betebenner, Thomas R. Herrin, Gondi N. Kumar, John M. Lipari, Laman Alani, Soumojeet Ghosh, Rong R. Gao, Dilip Kaul
  • Ligand analog-irreversible enzyme inhibitor conjugates
    Patent number: 4550163
    Abstract: The present invention encompasses a method for determining ligands in test samples comprising intermixing with the test sample a ligand analog-irreversible enzyme inhibitor conjugate and a binding protein bindable to the ligand and the ligand analog-irreversible enzyme inhibitor conjugate and wherein the amount of ligand analog-irreversible enzyme inhibitor conjugate bound by the binding protein is related to the amount of ligand in the test sample, said binding protein inactivating the irreversible enzyme inhibitor when bound to the ligand analog portion of the conjugate; intermixing an enzyme which is irreversibly inhibited by the ligand analog-irreversible enzyme inhibitor conjugate unbound by the binding protein; and intermixing substrate to the enzyme and monitoring the enzyme substrate reaction.The invention also includes ligand analog-irreversible enzyme inhibitor conjugates useful as reagents in practicing the method.
    Type: Grant
    Filed: January 26, 1981
    Date of Patent: October 29, 1985
    Assignee: Abbott Laboratories
    Inventors: Houston F. Voss, Jacob Plattner, Thomas R. Herrin
  • Phenobarbital enzyme inhibitors
    Patent number: 4543412
    Abstract: Phenobarbital conjugates for use as enzyme inhibitors having the formula: ##STR1## wherein Z is a biologically compatible counter ion, n and m is an integer from 2 to 6 and R and R.sub.1 are each lower alkyl.
    Type: Grant
    Filed: November 4, 1983
    Date of Patent: September 24, 1985
    Assignee: Abbott Laboratories
    Inventors: Charles A. Flentge, Thomas R. Herrin
  • Ristocetin .psi.-aglycone as an antibacterial agent
    Patent number: 4456593
    Abstract: Described is the use of .psi.-aglycone and other derivatives of ristocetin A as antibacterial agents.
    Type: Grant
    Filed: June 22, 1982
    Date of Patent: June 26, 1984
    Assignee: Abbott Laboratories
    Inventors: Thomas R. Herrin, Alford M. Thomas
  • Ligand analog-irreversible enzyme inhibitor conjugates and methods for use
    Patent number: 4273866
    Abstract: The present invention encompasses a method for determining ligands in test samples comprising intermixing with the test sample a ligand analog-irreversible enzyme inhibitor conjugate and a binding protein bindable to the ligand and the ligand analog-irreversible enzyme inhibitor conjugate and wherein the amount of ligand analog-irreversible enzyme inhibitor conjugate bound by the binding protein is related to the amount of ligand in the test sample, said binding protein inactivating the irreversible enzyme inhibitor when bound to the ligand analog portion of the conjugate; intermixing an enzyme which is irreversibly inhibited by the ligand analog-irreversible enzyme inhibitor conjugate unbound by the binding protein; and intermixing substrate to the enzyme and monitoring the enzyme substrate reaction.The invention also includes ligand analog-irreversible enzyme inhibitor conjugates useful as reagents in practicing the method.
    Type: Grant
    Filed: February 5, 1979
    Date of Patent: June 16, 1981
    Assignee: Abbott Laboratories
    Inventors: Houston F. Voss, Jacob Plattner, Thomas R. Herrin
  • Triglyceride ester of phosphonoacetic acid having antiviral activity
    Patent number: 4150125
    Abstract: A triglyceride carrying, in the .beta.-position, the anionic moiety of phosphonoacetic acid has been found to exhibit excellent activity against viral infections caused by a herpes virus.
    Type: Grant
    Filed: May 19, 1978
    Date of Patent: April 17, 1979
    Assignee: Abbott Laboratories
    Inventors: Thomas R. Herrin, John S. Fairgrieve