Patents by Inventor Thomas R. Parr

Thomas R. Parr has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10201587
    Abstract: The present invention is directed to methods of inhibition, delay of formation, treatment, prophylaxis and/or prevention of infections caused by bacteria that exhibit tolerance to antimicrobial agents, including slow growing, stationary-phase and biofilm forming bacteria, through the use of glycopeptide antibiotics, such as oritavancin.
    Type: Grant
    Filed: April 2, 2009
    Date of Patent: February 12, 2019
    Assignee: MELINTA THERAPEUTICS, INC.
    Inventors: Eve Neesham-Grenon, Gregory Moeck, Adam Belley, Thomas R. Parr, Jr., Adel Rafai Far
  • Patent number: 9220749
    Abstract: Glycopeptide antibiotics, such as oritavancin, demonstrate significant activity against both a vegetative form of C. difficile and C. difficile spores. Methods for the treatment, prophylaxis and prevention of C. difficile infection and disease in animals, including humans, are described.
    Type: Grant
    Filed: December 10, 2013
    Date of Patent: December 29, 2015
    Assignee: THE MEDICINES COMPANY
    Inventors: Mark Harvey Wilcox, Simon Baines, Dario Lehoux, Thomas R. Parr
  • Patent number: 8790579
    Abstract: Methods and systems for preparing catalyst, such as chromium catalysts, are provided. The valence of at least a portion of the catalyst sent to an activator is changed from Cr(III) to Cr(VI). The catalyst is prepared or activated continuously using a fluidization bed catalyst activator.
    Type: Grant
    Filed: December 11, 2012
    Date of Patent: July 29, 2014
    Assignee: Chevron Phillips Chemical Company LP
    Inventors: Elizabeth A. Benham, Max P. McDaniel, Ted H. Cymbaluk, Charles K. Newsome, Charles R. Nease, H. Kenneth Staffin, Thomas R. Parr
  • Patent number: 8778292
    Abstract: A multi-stage fluidized bed synthesizer and process for synthesizing trichlorosilane wherein silicon particles can be fed into one of multiple intercommunicating fluidizing zones in a fluidized bed reactor supplied with fluidizing gas comprising hydrogen chloride. The fluidizing zones can be disposed laterally adjacent one to another, for example side-by-side, or in a horizontal line. Useful embodiments include: feeding the fluidizing gas at different rates and/or compositions to the different fluidizing zones; filtration apparatus to filter the gaseous product and return silicon particles to the reactor and cooling systems for cooling the fluidized bed and the gas volumes above the fluidized beds, if present.
    Type: Grant
    Filed: May 11, 2010
    Date of Patent: July 15, 2014
    Assignee: Procedyne Corporation
    Inventors: H. Kenneth Staffin, Thomas R. Parr
  • Publication number: 20140100157
    Abstract: Glycopeptide antibiotics, such as oritavancin, demonstrate significant activity against both a vegetative form of C. difficile and C. difficile spores. Methods for the treatment, prophylaxis and prevention of C. difficile infection and disease in animals, including humans, are described.
    Type: Application
    Filed: December 10, 2013
    Publication date: April 10, 2014
    Applicant: THE MEDICINES COMPANY
    Inventors: Mark Harvey WILCOX, Simon BAINES, Dario LEHOUX, Thomas R. PARR
  • Patent number: 8629100
    Abstract: Glycopeptide antibiotics, such as oritavancin, demonstrate significant activity against both a vegetative form of C. difficile and C. difficile spores. Methods for the treatment, prophylaxis and prevention of C. difficile infection and disease in animals, including humans, are described.
    Type: Grant
    Filed: July 24, 2013
    Date of Patent: January 14, 2014
    Assignee: The Medicines Company
    Inventors: Mark Harvey Wilcox, Simon Baines, Dario Lehoux, Thomas R. Parr
  • Publication number: 20130310308
    Abstract: Glycopeptide antibiotics, such as oritavancin, demonstrate significant activity against both a vegetative form of C. difficile and C. difficile spores. Methods for the treatment, prophylaxis and prevention of C. difficile infection and disease in animals, including humans, are described.
    Type: Application
    Filed: July 24, 2013
    Publication date: November 21, 2013
    Applicant: The Medicines Company
    Inventors: Mark Harvey WILCOX, Simon BAINES, Dario LEHOUX, Thomas R. PARR
  • Patent number: 8518873
    Abstract: Glycopeptide antibiotics, such as oritavancin, demonstrate significant activity against both a vegetative form of C. difficile and C. difficile spores. Methods for the treatment, prophylaxis and prevention of C. difficile infection and disease in animals, including humans, are described.
    Type: Grant
    Filed: September 11, 2008
    Date of Patent: August 27, 2013
    Assignee: The Medicines Company
    Inventors: Mark Harvey Wilcox, Simon Baines, Dario Lehoux, Thomas R. Parr
  • Patent number: 8420592
    Abstract: Glycopeptide antibiotics, such as oritavancin, demonstrate significant activity against a wide range of bacteria. Methods for the treatment, prophylaxis and prevention of bacterial infection and disease in animals, including humans, using a single dose of oritavancin over the course of therapy, are described.
    Type: Grant
    Filed: August 29, 2009
    Date of Patent: April 16, 2013
    Assignee: The Medicines Company
    Inventors: Dario Lehoux, Thomas R. Parr, Gregory Moeck, Pierre Etienne
  • Patent number: 8349264
    Abstract: Methods and systems for preparing catalyst, such as chromium catalysts, are provided. The valence of at least a portion of the catalyst sent to an activator is changed from Cr(III) to Cr(VI). The catalyst is prepared or activated continuously using a fluidization bed catalyst activator.
    Type: Grant
    Filed: January 5, 2012
    Date of Patent: January 8, 2013
    Assignee: Chevron Phillips Chemical Company LP
    Inventors: Elizabeth A. Benham, Max P. McDaniel, Ted H. Cymbaluk, Charles K. Newsome, Charles R. Nease, H. Kenneth Staffin, Thomas R. Parr
  • Publication number: 20120108768
    Abstract: Methods and systems for preparing catalyst, such as chromium catalysts, are provided. The valence of at least a portion of the catalyst sent to an activator is changed from Cr(III) to Cr(VI). The catalyst is prepared or activated continuously using a fluidization bed catalyst activator.
    Type: Application
    Filed: January 5, 2012
    Publication date: May 3, 2012
    Applicant: CHEVRON PHILLIPS CHEMICAL COMPANY LP
    Inventors: Elizabeth A. BENHAM, Max P. MCDANIEL, Ted H. CYMBALUK, Charles K. NEWSOME, Charles R. NEASE, H. Kenneth STAFFIN, Thomas R. PARR
  • Patent number: 8114353
    Abstract: Methods and systems for preparing catalyst, such as chromium catalysts, are provided. The valence of at least a portion of the catalyst sent to an activator is changed from Cr(III) to Cr(VI). The catalyst is prepared or activated continuously using a fluidization bed catalyst activator.
    Type: Grant
    Filed: December 20, 2007
    Date of Patent: February 14, 2012
    Assignee: Chevron Phillips Chemical Company LP
    Inventors: Elizabeth A. Benham, Max P. McDaniel, Ted H. Cymbaluk, Charles K. Newsome, Charles R. Nease, H. Kenneth Staffin, Thomas R. Parr
  • Publication number: 20110201546
    Abstract: Glycopeptide antibiotics, such as oritavancin, demonstrate significant activity against a wide range of bacteria. Methods for the treatment, prophylaxis and prevention of bacterial infection and disease in animals, including humans, using a single dose of oritavancin over the course of therapy, are described.
    Type: Application
    Filed: August 29, 2009
    Publication date: August 18, 2011
    Applicant: TARGANTA THERAPEUTICS CORP.
    Inventors: Dario Lehoux, Thomas R Parr, Gregory Moeck, Pierre Etienne
  • Publication number: 20110046041
    Abstract: The present invention is directed to methods of inhibition, delay of formation, treatment, prophylaxis and/or prevention of infections caused by bacteria that exhibit tolerance to antimicrobial agents, including slow growing, stationary-phase and biofilm forming bacteria, through the use of glycopeptide antibiotics, such as oritavancin.
    Type: Application
    Filed: April 2, 2009
    Publication date: February 24, 2011
    Applicant: TARGANTA THERAPEUTICS CORP.
    Inventors: Eve Neesham-Grenon, Gregory Moeck, Adam Belley, Thomas R. Parr, JR., Adel Rafai Far
  • Publication number: 20100311646
    Abstract: Glycopeptide antibiotics, such as oritavancin, demonstrate significant activity against both a vegetative form of C. difficile and C. difficile spores. Methods for the treatment, prophylaxis and prevention of C. difficile infection and disease in animals, including humans, are described.
    Type: Application
    Filed: September 11, 2008
    Publication date: December 9, 2010
    Applicant: TARGANTA THERAPEUTICS CORP.
    Inventors: Mark Harvey Wilcox, Simon Baines, Dario Lehoux, Thomas R. Parr
  • Publication number: 20100290970
    Abstract: A multi-stage fluidized bed synthesizer and process for synthesizing trichlorosilane wherein silicon particles can be fed into one of multiple intercommunicating fluidizing zones in a fluidized bed reactor supplied with fluidizing gas comprising hydrogen chloride. The fluidizing zones can be disposed laterally adjacent one to another, for example side-by-side, or in a horizontal line. Useful embodiments include: feeding the fluidizing gas at different rates and/or compositions to the different fluidizing zones; filtration apparatus to filter the gaseous product and return silicon particles to the reactor and cooling systems for cooling the fluidized bed and the gas volumes above the fluidized beds, if present.
    Type: Application
    Filed: May 11, 2010
    Publication date: November 18, 2010
    Inventors: H. Kenneth STAFFIN, Thomas R. Parr
  • Publication number: 20090164046
    Abstract: Methods and systems for preparing catalyst, such as chromium catalysts, are provided. The valence of at least a portion of the catalyst sent to an activator is changed from Cr(III) to Cr(VI). The catalyst is prepared or activated continuously using a fluidization bed catalyst activator.
    Type: Application
    Filed: December 20, 2007
    Publication date: June 25, 2009
    Applicant: Chevron Phillips Chemical Company LP
    Inventors: Elizabeth A. Benham, Max P. McDaniel, Ted H. Cymbaluk, Charles K. Newsome, Charles R. Nease, H. Kenneth Staffin, Thomas R. Parr
  • Patent number: 5796018
    Abstract: Ferrous powder particles are coated with vaporized phosphorus in a fluid-bed reactor to obtain homogeneous coatings of phosphorus. The coated powders are useful feed for pressed structural parts, exhibiting improved green density, compressibility and sintered density thus improving magnetic and tensile properties.
    Type: Grant
    Filed: January 29, 1997
    Date of Patent: August 18, 1998
    Assignees: Procedyne Corp., Magna-Tech P/M Labs.
    Inventors: Kenneth H. Moyer, David J. Geveke, Thomas R. Parr, Robert B. Roaper