Patents by Inventor Thomas R. Parr
Thomas R. Parr has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10201587Abstract: The present invention is directed to methods of inhibition, delay of formation, treatment, prophylaxis and/or prevention of infections caused by bacteria that exhibit tolerance to antimicrobial agents, including slow growing, stationary-phase and biofilm forming bacteria, through the use of glycopeptide antibiotics, such as oritavancin.Type: GrantFiled: April 2, 2009Date of Patent: February 12, 2019Assignee: MELINTA THERAPEUTICS, INC.Inventors: Eve Neesham-Grenon, Gregory Moeck, Adam Belley, Thomas R. Parr, Jr., Adel Rafai Far
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Patent number: 9220749Abstract: Glycopeptide antibiotics, such as oritavancin, demonstrate significant activity against both a vegetative form of C. difficile and C. difficile spores. Methods for the treatment, prophylaxis and prevention of C. difficile infection and disease in animals, including humans, are described.Type: GrantFiled: December 10, 2013Date of Patent: December 29, 2015Assignee: THE MEDICINES COMPANYInventors: Mark Harvey Wilcox, Simon Baines, Dario Lehoux, Thomas R. Parr
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Patent number: 8790579Abstract: Methods and systems for preparing catalyst, such as chromium catalysts, are provided. The valence of at least a portion of the catalyst sent to an activator is changed from Cr(III) to Cr(VI). The catalyst is prepared or activated continuously using a fluidization bed catalyst activator.Type: GrantFiled: December 11, 2012Date of Patent: July 29, 2014Assignee: Chevron Phillips Chemical Company LPInventors: Elizabeth A. Benham, Max P. McDaniel, Ted H. Cymbaluk, Charles K. Newsome, Charles R. Nease, H. Kenneth Staffin, Thomas R. Parr
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Patent number: 8778292Abstract: A multi-stage fluidized bed synthesizer and process for synthesizing trichlorosilane wherein silicon particles can be fed into one of multiple intercommunicating fluidizing zones in a fluidized bed reactor supplied with fluidizing gas comprising hydrogen chloride. The fluidizing zones can be disposed laterally adjacent one to another, for example side-by-side, or in a horizontal line. Useful embodiments include: feeding the fluidizing gas at different rates and/or compositions to the different fluidizing zones; filtration apparatus to filter the gaseous product and return silicon particles to the reactor and cooling systems for cooling the fluidized bed and the gas volumes above the fluidized beds, if present.Type: GrantFiled: May 11, 2010Date of Patent: July 15, 2014Assignee: Procedyne CorporationInventors: H. Kenneth Staffin, Thomas R. Parr
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Publication number: 20140100157Abstract: Glycopeptide antibiotics, such as oritavancin, demonstrate significant activity against both a vegetative form of C. difficile and C. difficile spores. Methods for the treatment, prophylaxis and prevention of C. difficile infection and disease in animals, including humans, are described.Type: ApplicationFiled: December 10, 2013Publication date: April 10, 2014Applicant: THE MEDICINES COMPANYInventors: Mark Harvey WILCOX, Simon BAINES, Dario LEHOUX, Thomas R. PARR
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Patent number: 8629100Abstract: Glycopeptide antibiotics, such as oritavancin, demonstrate significant activity against both a vegetative form of C. difficile and C. difficile spores. Methods for the treatment, prophylaxis and prevention of C. difficile infection and disease in animals, including humans, are described.Type: GrantFiled: July 24, 2013Date of Patent: January 14, 2014Assignee: The Medicines CompanyInventors: Mark Harvey Wilcox, Simon Baines, Dario Lehoux, Thomas R. Parr
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Publication number: 20130310308Abstract: Glycopeptide antibiotics, such as oritavancin, demonstrate significant activity against both a vegetative form of C. difficile and C. difficile spores. Methods for the treatment, prophylaxis and prevention of C. difficile infection and disease in animals, including humans, are described.Type: ApplicationFiled: July 24, 2013Publication date: November 21, 2013Applicant: The Medicines CompanyInventors: Mark Harvey WILCOX, Simon BAINES, Dario LEHOUX, Thomas R. PARR
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Patent number: 8518873Abstract: Glycopeptide antibiotics, such as oritavancin, demonstrate significant activity against both a vegetative form of C. difficile and C. difficile spores. Methods for the treatment, prophylaxis and prevention of C. difficile infection and disease in animals, including humans, are described.Type: GrantFiled: September 11, 2008Date of Patent: August 27, 2013Assignee: The Medicines CompanyInventors: Mark Harvey Wilcox, Simon Baines, Dario Lehoux, Thomas R. Parr
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Patent number: 8420592Abstract: Glycopeptide antibiotics, such as oritavancin, demonstrate significant activity against a wide range of bacteria. Methods for the treatment, prophylaxis and prevention of bacterial infection and disease in animals, including humans, using a single dose of oritavancin over the course of therapy, are described.Type: GrantFiled: August 29, 2009Date of Patent: April 16, 2013Assignee: The Medicines CompanyInventors: Dario Lehoux, Thomas R. Parr, Gregory Moeck, Pierre Etienne
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Patent number: 8349264Abstract: Methods and systems for preparing catalyst, such as chromium catalysts, are provided. The valence of at least a portion of the catalyst sent to an activator is changed from Cr(III) to Cr(VI). The catalyst is prepared or activated continuously using a fluidization bed catalyst activator.Type: GrantFiled: January 5, 2012Date of Patent: January 8, 2013Assignee: Chevron Phillips Chemical Company LPInventors: Elizabeth A. Benham, Max P. McDaniel, Ted H. Cymbaluk, Charles K. Newsome, Charles R. Nease, H. Kenneth Staffin, Thomas R. Parr
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Publication number: 20120108768Abstract: Methods and systems for preparing catalyst, such as chromium catalysts, are provided. The valence of at least a portion of the catalyst sent to an activator is changed from Cr(III) to Cr(VI). The catalyst is prepared or activated continuously using a fluidization bed catalyst activator.Type: ApplicationFiled: January 5, 2012Publication date: May 3, 2012Applicant: CHEVRON PHILLIPS CHEMICAL COMPANY LPInventors: Elizabeth A. BENHAM, Max P. MCDANIEL, Ted H. CYMBALUK, Charles K. NEWSOME, Charles R. NEASE, H. Kenneth STAFFIN, Thomas R. PARR
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Patent number: 8114353Abstract: Methods and systems for preparing catalyst, such as chromium catalysts, are provided. The valence of at least a portion of the catalyst sent to an activator is changed from Cr(III) to Cr(VI). The catalyst is prepared or activated continuously using a fluidization bed catalyst activator.Type: GrantFiled: December 20, 2007Date of Patent: February 14, 2012Assignee: Chevron Phillips Chemical Company LPInventors: Elizabeth A. Benham, Max P. McDaniel, Ted H. Cymbaluk, Charles K. Newsome, Charles R. Nease, H. Kenneth Staffin, Thomas R. Parr
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Publication number: 20110201546Abstract: Glycopeptide antibiotics, such as oritavancin, demonstrate significant activity against a wide range of bacteria. Methods for the treatment, prophylaxis and prevention of bacterial infection and disease in animals, including humans, using a single dose of oritavancin over the course of therapy, are described.Type: ApplicationFiled: August 29, 2009Publication date: August 18, 2011Applicant: TARGANTA THERAPEUTICS CORP.Inventors: Dario Lehoux, Thomas R Parr, Gregory Moeck, Pierre Etienne
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Publication number: 20110046041Abstract: The present invention is directed to methods of inhibition, delay of formation, treatment, prophylaxis and/or prevention of infections caused by bacteria that exhibit tolerance to antimicrobial agents, including slow growing, stationary-phase and biofilm forming bacteria, through the use of glycopeptide antibiotics, such as oritavancin.Type: ApplicationFiled: April 2, 2009Publication date: February 24, 2011Applicant: TARGANTA THERAPEUTICS CORP.Inventors: Eve Neesham-Grenon, Gregory Moeck, Adam Belley, Thomas R. Parr, JR., Adel Rafai Far
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Publication number: 20100311646Abstract: Glycopeptide antibiotics, such as oritavancin, demonstrate significant activity against both a vegetative form of C. difficile and C. difficile spores. Methods for the treatment, prophylaxis and prevention of C. difficile infection and disease in animals, including humans, are described.Type: ApplicationFiled: September 11, 2008Publication date: December 9, 2010Applicant: TARGANTA THERAPEUTICS CORP.Inventors: Mark Harvey Wilcox, Simon Baines, Dario Lehoux, Thomas R. Parr
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Publication number: 20100290970Abstract: A multi-stage fluidized bed synthesizer and process for synthesizing trichlorosilane wherein silicon particles can be fed into one of multiple intercommunicating fluidizing zones in a fluidized bed reactor supplied with fluidizing gas comprising hydrogen chloride. The fluidizing zones can be disposed laterally adjacent one to another, for example side-by-side, or in a horizontal line. Useful embodiments include: feeding the fluidizing gas at different rates and/or compositions to the different fluidizing zones; filtration apparatus to filter the gaseous product and return silicon particles to the reactor and cooling systems for cooling the fluidized bed and the gas volumes above the fluidized beds, if present.Type: ApplicationFiled: May 11, 2010Publication date: November 18, 2010Inventors: H. Kenneth STAFFIN, Thomas R. Parr
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Publication number: 20090164046Abstract: Methods and systems for preparing catalyst, such as chromium catalysts, are provided. The valence of at least a portion of the catalyst sent to an activator is changed from Cr(III) to Cr(VI). The catalyst is prepared or activated continuously using a fluidization bed catalyst activator.Type: ApplicationFiled: December 20, 2007Publication date: June 25, 2009Applicant: Chevron Phillips Chemical Company LPInventors: Elizabeth A. Benham, Max P. McDaniel, Ted H. Cymbaluk, Charles K. Newsome, Charles R. Nease, H. Kenneth Staffin, Thomas R. Parr
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Patent number: 5796018Abstract: Ferrous powder particles are coated with vaporized phosphorus in a fluid-bed reactor to obtain homogeneous coatings of phosphorus. The coated powders are useful feed for pressed structural parts, exhibiting improved green density, compressibility and sintered density thus improving magnetic and tensile properties.Type: GrantFiled: January 29, 1997Date of Patent: August 18, 1998Assignees: Procedyne Corp., Magna-Tech P/M Labs.Inventors: Kenneth H. Moyer, David J. Geveke, Thomas R. Parr, Robert B. Roaper