Patents by Inventor Thomas R Simpson

Thomas R Simpson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7964733
    Abstract: Compounds of Formula I wherein R1, A, R2, R3, R4, R5, n, m and q are as described in the specification, pharmaceutically-acceptable salts, methods of making, pharmaceutical compositions containing and methods for using the same.
    Type: Grant
    Filed: September 19, 2006
    Date of Patent: June 21, 2011
    Assignee: AstraZeneca AB
    Inventors: Jeffrey S. Albert, Gerard M. Koether, Cristobal Alhambra, James Kang, Thomas R. Simpson, James Woods, Yan Li
  • Publication number: 20100120850
    Abstract: Compounds of Formula (I) wherein R1, R2, n and R3 are as described in the specification, pharmaceutically-acceptable salts, methods of making, pharmaceutical compositions containing and methods for using the same.
    Type: Application
    Filed: March 18, 2008
    Publication date: May 13, 2010
    Inventors: James Kang, John P. MccAuley, Thomas R. Simpson
  • Patent number: 7608628
    Abstract: Compounds of Formula II wherein R1, A, R2, R3, R4, R5, R8, n, m and q are as described in the specification, pharmaceutically-acceptable salts, methods of making, pharmaceutical compositions containing and methods for using the same.
    Type: Grant
    Filed: December 11, 2006
    Date of Patent: October 27, 2009
    Assignee: AstraZeneca AB
    Inventors: Thomas R. Simpson, James Kang, Jeffrey S. Albert, Cristobal Alhambra, Gerald M. Koether, James Woods, Yan Li
  • Publication number: 20090012127
    Abstract: Compounds of Formula (I) wherein E, A and R1 are as described in the specification, pharmaceutically-acceptable salts, methods of making, pharmaceutical compositions containing and methods for using the same.
    Type: Application
    Filed: June 26, 2006
    Publication date: January 8, 2009
    Applicant: ASTRAZENECA AB
    Inventors: Thomas R. Simpson, Michael Balestra, Dean G. Brown, Cathy L. Dantzman, Glen E. Ernst, William Frietze, Christopher R. Holmquist, James Kang, Frances M. McLaren, Reed W. Smith, JR., James M. Woods
  • Publication number: 20080306087
    Abstract: The present invention relates to compounds of formula (I) and processes for preparing such compounds, their use in the treatment of obesity, psychiatric and neurological disorders, to methods for their therapeutic use and to pharmaceutical compositions containing them.
    Type: Application
    Filed: August 3, 2006
    Publication date: December 11, 2008
    Applicant: ASTRAZENECA AB
    Inventors: James R. Empfield, Michael Laplante, Megan Murphy King, Thomas R. Simpson, Maxime C. Tremblay, James M. Woods, Jingbo Yan
  • Publication number: 20080306110
    Abstract: Compounds of Formula I wherein R1, A, R2, R3, R4, R5, n, m and q are as described in the specification, pharmaceutically-acceptable salts, methods of making, pharmaceutical compositions containing and methods for using the same.
    Type: Application
    Filed: September 19, 2006
    Publication date: December 11, 2008
    Applicant: ASTRAZENECA AB
    Inventors: Jeffrey S. Albert, Cristobal Alhambra, James Kang, Gerard M. Koether, Thomas R. Simpson, James Woods, Yan Li
  • Publication number: 20080287492
    Abstract: Compounds of Formula I wherein R1, A, R2, R3, R4, R5, n, m and p are as described in the specification, pharmaceutically-acceptable salts, methods of making, pharmaceutical compositions containing and methods for using the same.
    Type: Application
    Filed: August 9, 2006
    Publication date: November 20, 2008
    Applicant: AstraZeneca AB
    Inventors: Jeffrey S. Albert, Cristobal Alhambra, James Kang, Gerard M. Koether, Thomas R. Simpson, James Woods, Yan Li
  • Publication number: 20080280949
    Abstract: Compounds of Formula I wherein R1, A, R2, R3, R4, R5, n, m and q are as described in the specification, pharmaceutically-acceptable salts, methods of making, pharmaceutical compositions containing and methods for using the same.
    Type: Application
    Filed: August 10, 2006
    Publication date: November 13, 2008
    Applicant: AstraZeneca AB
    Inventors: Jeffrey S. Albert, Cristobal Alhambra, James Kang, Gerard M. Koether, Thomas R. Simpson, James Woods, Yan Li
  • Publication number: 20080234269
    Abstract: Compounds of Formula I wherein R1, A, R2, R3, R4, R5, n, m and q are as described in the specification, pharmaceutically-acceptable salts, methods of making, pharmaceutical compositions containing and methods for using the same.
    Type: Application
    Filed: September 19, 2006
    Publication date: September 25, 2008
    Applicant: ASTRAZENECA AB
    Inventors: James B. Campbell, Jeffrey S. Albert, Cristobal Alhambra, James Kang, Gerard M. Koether, Thomas R. Simpson, James Woods, Yan Li
  • Publication number: 20080214605
    Abstract: Compounds of Formula I wherein R1, A, R2, R3, R4, R5, n, m and q are as described in the specification, pharmaceutically-acceptable salts, methods of making, pharmaceutical compositions containing and methods for using the same.
    Type: Application
    Filed: September 19, 2006
    Publication date: September 4, 2008
    Applicant: AstraZeneca AB
    Inventors: Jeffrey S. Albert, Gerard M. Koether, Cristobal Alhambra, James Kang, Thomas R. Simpson, James Woods, Yan Li
  • Publication number: 20080200504
    Abstract: Compounds of Formula (I) wherein R1, A, R2, R3, R4, R5,n, m and q are as described in the specification, pharmaceutically-acceptable salts, methods of making, pharmaceutical compositions containing and methods for using the same.
    Type: Application
    Filed: August 9, 2006
    Publication date: August 21, 2008
    Applicant: AstraZeneca AB
    Inventors: Jeffrey S. Albert, Cristobal Alhambra, James Kang, Gerard M. Koether, Thomas R. Simpson, James Woods, Yan Li
  • Publication number: 20080200500
    Abstract: Compounds of Formula I wherein R1, A, R2, n, R3, m, R5 and q are as described in the specification, pharmaceutically-acceptable salts, methods of making, pharmaceutical compositions containing and methods for using the same.
    Type: Application
    Filed: May 30, 2006
    Publication date: August 21, 2008
    Applicant: AstraZeneca AB
    Inventors: Thomas R. Simpson, James Kang, S. Jeffrey Albert, Cristobal Alhambra, M. Gerard Koether, M. James Woods, Yan Li
  • Publication number: 20080194622
    Abstract: Compounds of Formula I wherein R1, A, R2, R3, R4, R5 n, m and q are as described in the specification, pharmaceutically-acceptable salts, methods of making, pharmaceutical compositions containing and methods for using the same.
    Type: Application
    Filed: June 21, 2006
    Publication date: August 14, 2008
    Applicant: AstraZeneca AB
    Inventors: Thomas R. Simpson, James Kang, Jeffrey S. Albert, Cristobal Alhambra, Gerard M. Koether, James Woods, Yan Li
  • Patent number: 6417183
    Abstract: This invention provides substituted 1,2,3,4-tetrahydronaphthalene [3H]-emopamil binding site inhibitors useful in the treatment of neurological disorders. Such inhibitors are compounds of formula (I) wherein R, R1, m, R2 and n are as defined in the specification.
    Type: Grant
    Filed: June 15, 2000
    Date of Patent: July 9, 2002
    Assignee: Astrazenela UK Limited
    Inventors: Richard A Keith, Edward J Warawa, Thomas R Simpson
  • Patent number: PP6606
    Abstract: A new variety of Sargent crabapple tree particularly distinguished by its relatively short, low spreading and very horizontal form and a foliage coloration that is of a darker purplish green than the light green of the normal Sargent variety. The flowers of this new Sargent variety open to red to light pink with a red edging on the petals instead of the pure white flowers of the normal Sargent variety. This new crabapple tree flowers profusely and with its low horizontal form, the tree has a definite Oriental flavor quite unlike any other crabapple tree known to applicant.
    Type: Grant
    Filed: September 18, 1987
    Date of Patent: February 14, 1989
    Assignee: Simpson Orchard Company, Inc.
    Inventor: Thomas R. Simpson