Patents by Inventor Thomas R. Tice

Thomas R. Tice has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DEVICE AND METHODS FOR TREATING PARANASAL SINUS CONDITIONS
    Publication number: 20210378698
    Abstract: Described here are paranasal sinus devices for treating paranasal sinus conditions. The devices include a cavity member, ostial member, and nasal portion. One or more of the cavity member, ostial member, and nasal portion may deliver an active agent for sustained release to treat the paranasal sinus condition. Exemplary paranasal sinus conditions are sinus inflammation due to functional endoscopic sinus surgery (FESS) and rhinosinusitis.
    Type: Application
    Filed: August 17, 2021
    Publication date: December 9, 2021
    Inventors: Donald J. EATON, Thomas R. TICE, David B. DOWNIE, Patrick A. ARENSDORF, Rodney A. BRENNEMAN, Danielle L. CLAY
  • Device and methods for treating paranasal sinus conditions
    Patent number: 11123091
    Abstract: Described here are paranasal sinus devices for treating paranasal sinus conditions. The devices include a cavity member, ostial member, and nasal portion. One or more of the cavity member, ostial member, and nasal portion may deliver an active agent for sustained release to treat the paranasal sinus condition. Exemplary paranasal sinus conditions are sinus inflammation due to functional endoscopic sinus surgery (FESS) and rhinosinusitis.
    Type: Grant
    Filed: January 25, 2017
    Date of Patent: September 21, 2021
    Assignee: Intersect ENT, Inc.
    Inventors: Donald J. Eaton, Thomas R. Tice, David B. Downie, Patrick A. Arensdorf, Rodney A. Brenneman, Danielle L. Clay
  • Methods of inducing melanogenesis in a subject
    Patent number: 10857208
    Abstract: Described herein are methods and compositions for inducing melanogenesis in a human subject. The method comprises administering to a subject an alpha-MSH analogue, in an effective amount and time to induce melanogenesis by the melanocytes in epidermal tissue of subject without inducing homologous desensitization of the melanocortin-1 receptors.
    Type: Grant
    Filed: August 27, 2018
    Date of Patent: December 8, 2020
    Assignee: CLINUVEL PHARMACEUTICALS LIMITED
    Inventors: Michael John Kleinig, Thomas R. Tice, Jay K. Staas
  • METHODS OF INDUCING MELANOGENESIS IN A SUBJECT
    Publication number: 20180360919
    Abstract: Described herein are methods and compositions for inducing melanogenesis in a human subject. The method comprises administering to a subject an alpha-MSH analogue, in an effective amount and time to induce melanogenesis by the melanocytes in epidermal tissue of subject without inducing homologous desensitization of the melanocortin-1 receptors.
    Type: Application
    Filed: August 27, 2018
    Publication date: December 20, 2018
    Applicant: Clinuvel Pharmaceuticals Limited
    Inventors: Michael John KLEINIG, Thomas R. TICE, Jay K. STAAS
  • Methods of inducing melanogenesis in a subject
    Patent number: 10076555
    Abstract: Described herein are methods and compositions for inducing melanogenesis in a human subject. The method comprises administering to a subject an alpha-MSH analogue, in an effective amount and time to induce melanogenesis by the melanocytes in epidermal tissue of subject without inducing homologous desensitization of the melanocortin-1 receptors.
    Type: Grant
    Filed: April 21, 2016
    Date of Patent: September 18, 2018
    Assignee: Clinuvel Pharmaceuticals Limited
    Inventors: Michael John Kleinig, Thomas R. Tice, Jay K. Staas
  • DEVICE AND METHODS FOR TREATING PARANASAL SINUS CONDITIONS
    Publication number: 20170128093
    Abstract: Described here are paranasal sinus devices for treating paranasal sinus conditions. The devices include a cavity member, ostial member, and nasal portion. One or more of the cavity member, ostial member, and nasal portion may deliver an active agent for sustained release to treat the paranasal sinus condition. Exemplary paranasal sinus conditions are sinus inflammation due to functional endoscopic sinus surgery (FESS) and rhinosinusitis.
    Type: Application
    Filed: January 25, 2017
    Publication date: May 11, 2017
    Inventors: Donald J. EATON, Thomas R. TICE, David B. DOWNIE, Patrick A. ARENSDORF, Rodney A. BRENNEMAN, Danielle L. BIGGS
  • Device and methods for treating paranasal sinus conditions
    Patent number: 9585681
    Abstract: Described here are paranasal sinus devices for treating paranasal sinus conditions. The devices include a cavity member, ostial member, and nasal portion. One or more of the cavity member, ostial member, and nasal portion may deliver an active agent for sustained release to treat the paranasal sinus condition. Exemplary paranasal sinus conditions are sinus inflammation due to functional endoscopic sinus surgery (FESS) and rhinosinusitis.
    Type: Grant
    Filed: September 15, 2010
    Date of Patent: March 7, 2017
    Assignee: Intersect ENT, Inc.
    Inventors: Donald J. Eaton, Thomas R. Tice, David B. Downie, Patrick A. Arensdorf, Rodney A. Brenneman, Danielle L. Biggs
  • Compositions and methods for improved retention of a pharmaceutical composition at a local administration site
    Patent number: 9504643
    Abstract: Disclosed herein are compositions comprising cross-linkers for cross-linking a retention vehicle polymer. The compositions are particularly useful for local administration of a bioactive agent, wherein prolonged or extended availability of the bioactive agent at the site of administration is desired. Also disclosed are methods of delivering the compositions to a subject.
    Type: Grant
    Filed: March 29, 2011
    Date of Patent: November 29, 2016
    Assignee: Evonik Corporation
    Inventors: Thomas R. Tice, Kevin W. Burton
  • METHODS OF INDUCING MELANOGENESIS IN A SUBJECT
    Publication number: 20160235819
    Abstract: Described herein are methods and compositions for inducing melanogenesis in a human subject. The method comprises administering to a subject an alpha-MSH analogue, in an effective amount and time to induce melanogenesis by the melanocytes in epidermal tissue of subject without inducing homologous desensitization of the melanocortin-1 receptors.
    Type: Application
    Filed: April 21, 2016
    Publication date: August 18, 2016
    Applicant: Clinuvel Pharmaceuticals Limited
    Inventors: Michael John KLEINIG, Thomas R. TICE, Jay K. STAAS
  • Implantable suction cup composites and implants comprising same
    Patent number: 9415197
    Abstract: Described herein are implantable composites, kits comprising the composites, implant devices comprising the composites, and methods of making and using same, including point of use methods.
    Type: Grant
    Filed: December 21, 2009
    Date of Patent: August 16, 2016
    Assignee: SurModics, Inc.
    Inventor: Thomas R. Tice
  • Methods of inducing melanogenesis in a subject
    Patent number: 9345911
    Abstract: Described herein are methods and compositions for inducing melanogenesis in a human subject. The method comprises administering to a subject an alpha-MSH analogue, in an effective amount and time to induce melanogenesis by the melanocytes in epidermal tissue of subject without inducing homologous desensitization of the melanocortin-1 receptors.
    Type: Grant
    Filed: February 11, 2005
    Date of Patent: May 24, 2016
    Assignee: Clinuvel Pharmaceuticals Limited
    Inventors: Michael John Kleinig, Thomas R. Tice, Jay K. Staas
  • Controlled-Released Peptide Formulations
    Publication number: 20150148295
    Abstract: Described herein are methods and compositions for modulating the release and/or drug loading characteristics of encapsulated bioactive agents in polymer-based delivery systems via direct modification of the isoelectric point and/or net charge of the bioactive agent.
    Type: Application
    Filed: February 9, 2015
    Publication date: May 28, 2015
    Inventors: Kevin Burton, Torsten Woehr, Thomas R. Tice, Mimoun Ayoub
  • Flexible implantable composites and implants comprising same
    Patent number: 8951546
    Abstract: Described herein are implantable composites, kits comprising the composites, implant devices comprising the composites, and methods of making and using same, including point of use methods.
    Type: Grant
    Filed: December 21, 2009
    Date of Patent: February 10, 2015
    Assignee: SurModics Pharmaceuticals, Inc.
    Inventor: Thomas R. Tice
  • Controlled-released peptide formulations
    Patent number: 8951973
    Abstract: Described herein are methods and compositions for modulating the release and/or drug loading characteristics of encapsulated bioactive agents in polymer-based delivery systems via direct modification of the isoelectric point and/or net charge of the bioactive agent.
    Type: Grant
    Filed: August 28, 2009
    Date of Patent: February 10, 2015
    Inventors: Kevin Burton, Torsten Woehr, Thomas R. Tice, Mimoun Ayoub
  • DEVICES AND METHODS FOR DELIVERING ACTIVE AGENTS TO THE OSTEOMEATAL COMPLEX
    Publication number: 20140324025
    Abstract: Described here are devices, methods, and kits for treating sinusitis and related respiratory conditions by locally delivering active agents to the osteomeatal complex over a sustained period of time. The devices may be passively fixed within the osteomeatal complex and/or include one or more features that actively fix it within the osteomeatal complex. The devices may optionally include a portion that extends into a sinus ostium, sinus cavity, and/or the nasal passage to deliver an active agent.
    Type: Application
    Filed: July 9, 2014
    Publication date: October 30, 2014
    Inventors: Patrick A. ARENSDORF, Danielle L. BIGGS, Rodney BRENNEMAN, David B. DOWNIE, Donald J. EATON, Thomas R. TICE
  • Device and methods for treating paranasal sinus conditions
    Patent number: 8858974
    Abstract: Described here are paranasal sinus devices for treating paranasal sinus conditions. The devices include a cavity member, ostial member, and nasal portion. One or more of the cavity member, ostial member, and nasal portion may deliver an active agent for sustained release to treat the paranasal sinus condition. Exemplary paranasal sinus conditions are sinus inflammation due to functional endoscopic sinus surgery (FESS) and rhinosinusitis.
    Type: Grant
    Filed: November 13, 2008
    Date of Patent: October 14, 2014
    Assignee: Intersect ENT, Inc.
    Inventors: Donald J. Eaton, Thomas R. Tice, David B. Downie, Patrick A. Arensdorf, Rodney Brenneman, Danielle L. Biggs
  • Devices and methods for delivering active agents to the osteomeatal complex
    Patent number: 8802131
    Abstract: Described here are devices, methods, and kits for treating sinusitis and related respiratory conditions by locally delivering active agents to the osteomeatal complex over a sustained period of time. The devices may be passively fixed within the osteomeatal complex and/or include one or more features that actively fix it within the osteomeatal complex. The devices may optionally include a portion that extends into a sinus ostium, sinus cavity, and/or the nasal passage to deliver an active agent.
    Type: Grant
    Filed: August 14, 2009
    Date of Patent: August 12, 2014
    Assignee: Intersect ENT, Inc.
    Inventors: Patrick A. Arensdorf, Danielle L. Biggs, Rodney Brenneman, David B. Downie, Donald J. Eaton, Thomas R. Tice
  • Device and methods for treating paranasal sinus conditions
    Patent number: 8740839
    Abstract: Described here are paranasal sinus devices for treating paranasal sinus conditions. The devices include a cavity member, ostial member, and nasal portion. One or more of the cavity member, ostial member, and nasal portion may deliver an active agent for sustained release to treat the paranasal sinus condition. Exemplary paranasal sinus conditions are sinus inflammation due to functional endoscopic sinus surgery (FESS) and rhinosinusitis.
    Type: Grant
    Filed: September 15, 2010
    Date of Patent: June 3, 2014
    Assignee: Intersect ENT, Inc.
    Inventors: Donald J. Eaton, Thomas R. Tice, David B. Downie, Patrick A. Arensdorf, Rodney A. Brenneman, Danielle L. Biggs
  • Methods for Manufacturing Delivery Systems and Systems Thereof
    Publication number: 20140037707
    Abstract: Described herein are methods for reducing and achieving the desired release of an agent from a delivery system. The desired release kinetics are achieved by exposing the surface of the delivery system with a fluid for a desired period of time.
    Type: Application
    Filed: July 31, 2013
    Publication date: February 6, 2014
    Applicant: Evonik Corporation
    Inventors: Jay K. Staas, Thomas R. Tice, Bruce W. Hudson, Arthur J. Tipton
  • Methods for manufacturing delivery devices and devices thereof
    Patent number: 8541028
    Abstract: Described herein are methods for reducing and achieving the desired release of an agent from a delivery system. The desired release kinetics are achieved by exposing the surface of the delivery system with a fluid for a desired period of time.
    Type: Grant
    Filed: August 3, 2005
    Date of Patent: September 24, 2013
    Assignee: Evonik Corporation
    Inventors: Jay K. Staas, Thomas R. Tice, Bruce W. Hudson, Arthur J. Tipton