Patents by Inventor Thomas Rawson

Thomas Rawson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Serine Protease Inhibitors
    Publication number: 20070037813
    Abstract: Compounds having the structure shown below are useful to inhibit serine protease enzymes, such as TF/factor VIIa, factor Xa, thrombin and kallikrein. These compounds may be used in methods of preventing and/or treating clotting disorders.
    Type: Application
    Filed: September 29, 2006
    Publication date: February 15, 2007
    Applicant: Genentech, Inc.
    Inventors: Ignacio Aliagas-Martin, Dean Artis, Michael Dina, John Flygare, Richard Goldsmith, Regina Munroe, Alan Olivero, Richard Pastor, Thomas Rawson, Kirk Robarge, Daniel Sutherlin, Kenneth Weese, Aihe Zhou, Yan Zhu
  • ACYLSULFAMIDE INHIBITORS OF FACTOR VIIa
    Publication number: 20070037814
    Abstract: Compounds having the general formula I are useful for inhibiting serine protease enzymes, such as Tissue Factor VIIa, factor Xa, thrombin and kallikrein and have improved permeability properties. These compounds may be used in methods of preventing and/or treating clotting disorders.
    Type: Application
    Filed: October 2, 2006
    Publication date: February 15, 2007
    Applicant: Genentech, Inc.
    Inventors: Thomas Rawson, Lewis Gazzard
  • Pentacyclic kinase inhibitors
    Publication number: 20070037791
    Abstract: The invention provides novel kinase inhibitors that are useful as therapeutic agents for example in the treatment malignancies where the compounds have the general formula I wherein A, X, Y, Z, Ra, Rb, Rc, R1, R2, R3 and m are defined herein.
    Type: Application
    Filed: August 14, 2006
    Publication date: February 15, 2007
    Inventors: Thomas Rawson, Brian Safina, Jennafer Dotson, Aihe Zhou, Ignacio Aliagas-Martin, Jason Halladay, Jun Liang, Matthias Rueth, Bing-Yan Zhu
  • Low molecular weight peptidomimetic growth hormone secretagogues
    Publication number: 20060063807
    Abstract: The present invention comprises growth hormone releasing peptides/peptidomimetics (GHRP) capable of causing release of growth hormone from the pituitary. Compositions containing the GHRP's of this invention are used to promote growth in mammals either alone or in combination with other growth promoting compounds, especially IGF-1. In a method of this invention GHRP's in combination with IGF-1 are used to treat Type II diabetes. An exemplary compound of this invention is provided below.
    Type: Application
    Filed: May 25, 2005
    Publication date: March 23, 2006
    Applicant: Genentech, Inc.
    Inventors: Todd Somers, Kathleen Elias, Ross Clark, Robert McDowell, Mark Stanley, John Burnier, Thomas Rawson
  • Integrin receptor inhibitors
    Publication number: 20050187284
    Abstract: Provided are compounds of formula (I) wherein A, Q, W, X, Y, Z, R1 to R4, m and n are as defined herein. Compounds of the invention bind to ?4 integrin receptors and thereby inhibit binding of ligands for ?4 integrins which is useful for prophylactic and/or therapeutic treatment of diseases and conditions associated with ?4 integrins or their ligands.
    Type: Application
    Filed: April 20, 2005
    Publication date: August 25, 2005
    Applicant: Genentech, Inc.
    Inventors: Dean Artis, David Jackson, Thomas Rawson, Mark Reynolds, Daniel Sutherlin, Mark Stanley
  • Serine protease inhibitors
    Publication number: 20050186198
    Abstract: Compounds having the structure shown below are useful to inhibit serine protease enzymes, such as TF/factor VIIa, factor Xa, thrombin and kallikrein. These compounds may be used in methods of preventing and/or treating clotting disorders.
    Type: Application
    Filed: March 24, 2005
    Publication date: August 25, 2005
    Inventors: Ignacio Aliagas-Martin, Dean Artis, Michael Dina, John Flygare, Richard Goldsmith, Regina Munroe, Alan Olivero, Richard Pastor, Thomas Rawson, Kirk Robarge, Daniel Sutherlin, Kenneth Weese, Aihe Zhou, Yan Zhu