Abstract: Disclosed herein are novel cycloalka[b]heteroaryl compounds having CX3CR1/fractalkine receptor (CX3CR1) agonistic properties, pharmaceutical compositions comprising these compounds, chemical processes for preparing these compounds and their use in the treatment or prophylaxis of diseases associated with CX3CR1 receptor activity in animals, in particular humans.

Abstract: One embodiment of the present invention sets forth a technique for adding dimensions to a target drawing. The technique includes generating a first set of node embeddings for a first set of nodes included in a target graph that represents the target drawing. The technique also includes receiving a second set of node embeddings for a second set of nodes included in a source graph that represents a source drawing, where one or more nodes included in the second set of nodes are associated with one or more source dimensions included in the source drawing. The technique further includes generating a set of mappings between the first and second sets of nodes based similarities between the first set of node embeddings and the second set of node embeddings, and automatically placing the one or more source dimensions within the target drawing based on the set of mappings.

Abstract: Systems and methods for efficiently managing bulk material are provided. The disclosure is directed to a portable support structure used to receive one or more portable containers of bulk material and output bulk material from the containers directly into the blender hopper. The portable support structure may include a frame for receiving and holding the one or more portable bulk material containers in an elevated position proximate the blender hopper, as well as one or more gravity feed outlets for routing the bulk material from the containers directly into the blender hopper. In some embodiments, the portable support structure may be transported to the well site on a trailer, unloaded from the trailer, and positioned proximate the blender unit. In other embodiments, the portable support structure may be a mobile support structure that is integrated into a trailer unit.

Abstract: Various techniques facilitate the development of an image library that can be used to train and/or validate an automated visual inspection (AVI) model, such an AVI neural network for image classification. In one aspect, an arithmetic transposition algorithm is used to generate synthetic images from original images by transposing features (e.g., defects) onto the original images, with pixel-level realism. In other aspects, digital inpainting techniques are used to generate realistic synthetic images from original images. Deep learning-based inpainting techniques may be used to add, remove, and/or modify defects or other depicted features. In still other aspects, quality control techniques are used to assess the suitability of image libraries for training and/or validation of AVI models, and/or to assess whether individual images are suitable for inclusion in such libraries.

Abstract: Absorbent articles with front and rear opening features are disclosed. An article may comprise an insert comprising an outer cover, a liner, and a core between the outer cover and liner, a first waist panel coupled to the insert throughout a first attachment region, and a second waist panel coupled to the insert throughout a second attachment region, the second panel being coupled to the first panel proximate a first side edge of the article and the second side edge of the article and further comprising a weakened region. The second attachment may comprise a low-strength attachment zone and a high-strength attachment zone, the high-strength attachment zone disposed proximate the attachment region bottom edge. The low-strength attachment zone may further have a first peel strength and the high-strength attachment zone may have a second peel strength, the second peel strength greater than the first.

Abstract: The present technology provides rechargeable alkali metal-sulfur galvanic cells and batteries incorporating such cells as well as methods of using such cell and batteries. The present galvanic cells provide high specific energy and high power at lower cost than conventional alkali metal-sulfur cells.

Abstract: Systems and methods for efficient upstream multicast in passive optical networks. An upstream multicast source communicates an upstream multicast packet to the network. Subsequent downstream packet management achieved through use of source filters prevents a reflected copy of the original upstream multicast packets from being received by the upstream multicast source.

Abstract: Absorbent articles with front and rear opening features are disclosed. An article may comprise an absorbent insert comprising an outer cover, a liner, and a core between the outer cover and liner, a first waist panel coupled to the insert and having a first waist panel bottom edge, a first waist panel top edge, a first waist panel outer surface, and a first waist panel inner surface, and a second waist panel coupled to the insert. The first waist panel may be coupled to the second waist panel along side edges of the article, and the first waist panel may further comprise a weakened region comprising weakened portions extending at least partially between the first waist panel bottom edge and the first waist panel top edge. The weakened region may have a weakened region percentage of between about 45% and about 90%.

Abstract: An dual oral composition is provided having a first peroxide-containing component and a second bicarbonate-containing component having exceptional anti-plaque and antibacterial action with re-mineralization properties.

Abstract: A fan brake system for controlling an industrial fan system, the fan brake system including a fan brake having a brake pad movable on the fan brake to selectively engage the fan system. An actuator including a motor can be operable to cause the fan brake to perform a braking procedure on the fan system to resist rotational movement of the fan system. A controller can be communicated with the actuator, the controller operable to selectively cause the actuator and the fan brake to perform the braking procedure, wherein the controller is operable to monitor and control power being supplied to the motor of the actuator during the braking procedure to maintain a torque output of the motor according to a predetermined torque profile during the braking procedure.

Abstract: New dual temperature electrochemical methods and systems for the production of sodium metal from sodium polysulfides have been discovered. The technology provides high conductivity for sodium ions and extended service life for the electrochemical cell.

Abstract: The flow of well treatment fluids may be diverted from a high permeability zone to a low permeability zone within a fracture network within a subterranean formation by use of a mixture comprising a dissolvable diverter and a proppant. At least a portion of the high permeability zone is propped open with the proppant of the mixture and at least a portion of the high permeability zone is blocked with the diverter. A fluid is then pumped into the subterranean formation and into a lower permeability zone of the formation farther from the wellbore. The diverter in the high permeability zones may then be dissolved at in-situ reservoir conditions and hydrocarbons produced from the high permeability propped zones of the fracture network. The mixture has particular applicability in the enhancement of production or hydrocarbons from high permeability zones in a fracture network located near the wellbore.

Abstract: A fan brake system for controlling an industrial fan system, the fan brake system including a fan brake having a brake pad movable on the fan brake to selectively engage the fan system. An actuator including a motor can be operable to cause the fan brake to perform a braking procedure on the fan system to resist rotational movement of the fan system. A controller can be communicated with the actuator, the controller operable to selectively cause the actuator and the fan brake to perform the braking procedure, wherein the controller is operable to monitor and control power being supplied to the motor of the actuator during the braking procedure to maintain a torque output of the motor according to a predetermined torque profile during the braking procedure.

Abstract: The present invention provides compositions and methods related to the cell surface protein CRB1 for the treatment of retinopathies in a subject, as well as systems and kits employing such compositions.

Abstract: Systems and methods for efficient upstream multicast in passive optical networks. An upstream multicast source communicates an upstream multicast packet to the network. Subsequent downstream packet management achieved through use of source filters prevents a reflected copy of the original upstream multicast packets from being received by the upstream multicast source.

Abstract: The present technology provides rechargeable alkali metal-sulfur galvanic cells and batteries incorporating such cells as well as methods of using such cell and batteries. The present galvanic cells provide high specific energy and high power at lower cost than conventional alkali metal-sulfur cells.

Abstract: New dual temperature electrochemical methods and systems for the production of sodium metal from sodium polysulfides have been discovered. The technology provides high conductivity for sodium ions and extended service life for the electrochemical cell.

Abstract: The complexity of a fracture network may be enhanced during a hydraulic fracturing operation by monitoring operational parameters of the fracturing job and altering stress conditions in the well in response to the monitoring of the operational parameters. The operational parameters monitored may include the injection rate of the pumped fluid, the density of the pumped fluid or the bottomhole pressure of the well after the fluid is pumped. The method provides an increase to the stimulated reservoir volume (SRV).

Abstract: A fan brake system for controlling an industrial fan system, the fan brake system including a fan brake having a brake pad movable on the fan brake to selectively engage the fan system. An actuator including a motor can be operable to cause the fan brake to perform a braking procedure on the fan system to resist rotational movement of the fan system. A controller can be communicated with the actuator, the controller operable to selectively cause the actuator and the fan brake to perform the braking procedure, wherein the controller is operable to monitor and control power being supplied to the motor of the actuator during the braking procedure to maintain a torque output of the motor according to a predetermined torque profile during the braking procedure.

Abstract: Systems and methods for efficient upstream multicast in passive optical networks. An upstream multicast source communicates an upstream multicast packet to the network. Subsequent downstream packet management achieved through use of source filters prevents a reflected copy of the original upstream multicast packets from being received by the upstream multicast source.