Abstract: Provided herein are FGFR1/KLB targeting agonistic antigen-binding proteins, or fragments thereof, having improved physico-chemical properties. Also provided herein are conjugates comprising an FGFR1/KLB targeting agonistic antigen-binding protein, or a fragment thereof, and at least one GLP-1R agonistic peptide. Further provided are pharmaceutical compositions comprising the antibody (or fragment thereof), or the conjugate provided herein, and the use of the antibody (or fragment thereof), or the use of the conjugate in medicine.

Abstract: An additive printer dispenses filament having high volume content of axial reinforcing fibers impregnated with a partially cured thermoset material. Partial curing provides sufficient mechanical integrity for high-density fiber support and retention while maintaining tackiness necessary to allow layer by layer additive construction. The complete construction may then be heated to provide complete curing.

Abstract: The description relates to safely and accurately testing high-power computer rack power supplies. One example can include a computer rack that includes multiple computers and a high-power computer rack supply (HPCRS) lead terminating in a connector. The HPCRS lead includes multiple conductors and is configured to couple to the computer rack to power the multiple computers. This example can include a full-spectrum computer rack power supply testing (FSCRPST) device configured to test the power from the HPCRS lead.

Abstract: A roof module for connection to a motor vehicle having a transparent solid roof portion, which forms a see-through roof area and which is immobile relative to the vehicle body when the roof module is in the installed position, and/or a roof opening system having a mobile lid element, by means of which a roof opening can be opened or closed at will, and a closed roof skin, which forms the see-through roof area and/or is adjacent to the roof opening and forms a roof cover outside of the see-through roof area and/or the roof opening. At least one sensor module can be provided having at least one environment sensor for detecting a vehicle environment and is disposed outside of the see-through roof area and/or the roof opening and is covered by the roof skin.

Abstract: The present invention relates to sunscreen compositions containing bis-ethylhexyloxyphenol methoxy phenyl triazine (BEMT) and at least one film forming agent selected from the group consisting of citrate crosspolymers and polyamides in combination with an alkandiol with the proviso that the composition is free of octocrylene, ethylhexyl triazone, diethylamino hydroxy benzoyl hexyl benzoate and ethylhexyl methoxycinnamate. Said compositions exhibit a reduced soaping effect and thus a more appealing skin feel and look.

Abstract: The present invention relates to sunscreen compositions containing bis-ethylhexyloxyphenol methoxyphenyl triazine (BEMT) and menthyl anthranilate. Said compositions exhibit a reduced fluorescence and an appealing skin feel and look.

Abstract: The present invention relates to sunscreen compositions containing as UV filters solely a combination of i) bis-ethylhexyloxyphenol methoxyphenyl triazine (BEMT) and (ii) at least two pigmentary UV-filters. Said compositions exhibit an appealing skin feel and look.

Abstract: A roof module for a motor vehicle may have a roof skin, a roof frame on a vehicle body and have at least one transverse frame part extending in the transverse roof direction and a longitudinal frame part extending in the longitudinal roof direction on either side of a longitudinal center roof plane, and a roof opening system having a lid element configured to be displaced on guide rails, which are part of the longitudinal frame parts of the roof frame, in the longitudinal roof direction relative to the roof frame, and/or a solid roof element having a transparent see-through portion and being rigidly connected to the roof frame, having a sensor system comprising at least one sensor module which has at least one environmental sensor and is located outside of the roof opening and/or outside of the transparent see-through portions and is covered by a cover element.

Abstract: The present invention relates to a topical preparation comprising a UV filter combination of certain microfine zinc oxide, 2,4-bis{[4-(2-ethylhexyloxy)-2-hydroxy]phenyl}-6-(4-methoxyphenyl)-1,3,5-triazine (INCI: Bis-Ethylhexyloxyphenol methoxyphenyl Triazine), 2-phenylbenzimidazole-5-sulfonic acid and/or one or more salts thereof and 2,4,6-tris[anilino(p-carbo-2?-ethyl-1?-hexyloxy)]-1,3,5-triazine (INCI: Ethylhexyl Triazone).

Abstract: The present invention relates to a topical preparation comprising a UV filter combination of certain microfine zinc oxide, 2,4-bis{[4-(2-ethylhexyloxy)-2-hydroxy]phenyl}-6-(4-methoxyphenyl)-1,3,5-triazine (INCI: Bis-Ethylhexyloxyphenol methoxyphenyl Triazine), 2-phenylbenzimidazole-5-sulfonic acid and/or one or more salts thereof and 4,4?-((6((4 (((1,1-dimethylethyl)amino)carbonyl)phenyl)-amino)-1,3,5-triazine-2,4-diyl)diimino)bis(2-ethylhexyl)benzoate (INCI: Diethylhexyl butamido triazone).

Abstract: A roof module for connection to a motor vehicle having a transparent solid roof portion, which forms a see-through roof area and which is immobile relative to the vehicle body when the roof module is in the installed position, and/or a roof opening system having a mobile lid element, by means of which a roof opening can be opened or closed at will, and a closed roof skin, which forms the see-through roof area and/or is adjacent to the roof opening and forms a roof cover outside of the see-through roof area and/or the roof opening. At least one sensor module can be provided having at least one environment sensor for detecting a vehicle environment and is disposed outside of the see-through roof area and/or the roof opening and is covered by the roof skin.

Abstract: The present invention relates to topical compositions comprising erythrulose and hydroxyacetophenone as well as the use thereof for the prevention and/or treatment of ailments associated with Malassezia yeast, Propionibacterium acnes as well as the protection against molds such as in particular Aspergillus brasiliensis.

Abstract: A roof module for a motor vehicle may have a roof skin, a roof frame on a vehicle body and have at least one transverse frame part extending in the transverse roof direction and a longitudinal frame part extending in the longitudinal roof direction on either side of a longitudinal center roof plane, and a roof opening system having a lid element configured to be displaced on guide rails, which are part of the longitudinal frame parts of the roof frame, in the longitudinal roof direction relative to the roof frame, and/or a solid roof element having a transparent see-through portion and being rigidly connected to the roof frame, having a sensor system comprising at least one sensor module which has at least one environmental sensor and is located outside of the roof opening and/or outside of the transparent see-through portions and is covered by a cover element.

Abstract: The present invention relates to topical compositions comprising erythrulose and a caprylate, characterized in that the amount of the caprylate in the composition is 5 higher than the amount of erythrulose.

Abstract: The present invention relates to topical composition comprising a cetyl phosphate surfactant mixture consisting essentially of mono- and/or dicetyl esters of phosphoric acid or salts thereof and cetylalcohol and inorganic phosphate and heavy metals and water, characterized in that the surfactant mixture contains no organochlorine impurities and has an inorganic phosphate content of less than 0.7 wt.-% and a heavy metal content of less than 12 ppm.

Abstract: The present invention relates to the use of erythrulose as antimicrobial agent as well as to composition comprising said agent.

Abstract: A method for determining a digital voltage replica for a substation. The method includes obtaining a substation topology and generating a node model from the substation topology. The generated model represents each switchgear by a pair of two connectivity nodes. The method further includes obtaining switchgear status data and animating the node model. When the node model is animated, the method allows determining a reference node for a target connectivity node. In this manner, a digital voltage replica of a substation is obtained.