Patents by Inventor Thomas Ruhland

Thomas Ruhland has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7834008
    Abstract: The present invention relates to cyclopropyl derivatives of formula (I) and salt thereof. These compounds are NK3 receptor antagonists and may therefore be useful for treatment of diseases where the NK3 receptor is implicated, e.g. psychotic disorders.
    Type: Grant
    Filed: August 13, 2004
    Date of Patent: November 16, 2010
    Assignee: H. Lundbeck A/S
    Inventors: Jan Kehler, Tore Hansen, Anders Poulsen, Berith Bjørnholm, Thomas Ruhland, Morten Bang Nørgaard, Søren Møller Nielsen
  • Patent number: 7732463
    Abstract: The invention provides compounds represented by the general formula (I) wherein the substituents are defined in the application. The compounds are useful in the treatment of an affective disorder, including depression, anxiety disorders including general anxiety disorder and panic disorder and obsessive compulsive disorder.
    Type: Grant
    Filed: April 2, 2004
    Date of Patent: June 8, 2010
    Assignee: H. Lundbeck A/S
    Inventors: Ask Puschl, Benny Bang-Andersen, Morten Jorgensen, Thomas Ruhland, Tine B. Stensbol
  • Patent number: 7683053
    Abstract: The invention provides compounds represented by the general formula I wherein the substituents are defined in the application. The compounds are useful in the treatment of an affective disorder, including depression, anxiety disorders including general anxiety disorder and panic disorder and obsessive compulsive disorder.
    Type: Grant
    Filed: October 19, 2006
    Date of Patent: March 23, 2010
    Assignee: H. Lundbeck A/S
    Inventors: Thomas Ruhland, Garrick Paul Smith, Benny Bang-Andersen, Ejner Knud Moltzen, Kim Andersen
  • Publication number: 20090181083
    Abstract: A novel tablet product that in an easy, flexible and reproducible manner can be loaded with a relatively high amount of a pharmaceutically acceptable liquid formulation e.g. carrying a therapeutically, prophylactically and/or diagnostically active substance. The novel loadable tablet product may be produced in large-scale batches and stored until use and each batch or sub-batch may be loaded with the same or different pharmaceutically acceptable liquid formulations and/or active substances. A loadable tablet according to the invention has a porosity of 30% v/v or more. The invention also provides tablets that have been loaded with such a liquid formulation as well as a method for the preparation thereof.
    Type: Application
    Filed: June 27, 2005
    Publication date: July 16, 2009
    Applicant: LIFEBYCLE PHARMAS A/S
    Inventors: Per Holm, Jannie E. Holm, Thomas Ruhland, Simon Dalsgaard
  • Patent number: 7393845
    Abstract: A heteroaryl derivative having the formula (I).
    Type: Grant
    Filed: June 5, 2007
    Date of Patent: July 1, 2008
    Assignee: H. Lundbeck A/S
    Inventors: Mario Rottländer, Ejner Knud Moltzen, Ivan Mikkelsen, Thomas Ruhland, Kim Andersen, Christian Krog-Jensen
  • Publication number: 20080070308
    Abstract: A reagent delivering article capable of retaining liquid reagents, a method of pre-paring said articles and the use of said articles for loading liquid reagents is provided. Furthermore a reagent delivering article loaded with at least one liquid reagent, a method of preparing same and the use of said loaded article in solution phase chemistry, where said loaded reagent is released from said article into the solution is provided.
    Type: Application
    Filed: June 27, 2005
    Publication date: March 20, 2008
    Inventors: Thomas Ruhland, Per Holm
  • Patent number: 7342015
    Abstract: A heteroaryl derivative having the formula (I).
    Type: Grant
    Filed: June 27, 2002
    Date of Patent: March 11, 2008
    Assignee: H. Lundbeck A/S
    Inventors: Mario Rottländer, Ejner Knud Moltzen, Ivan Mikkelsen, Thomas Ruhland, Kim Andersen, Christian Krog-Jensen
  • Publication number: 20080027071
    Abstract: A heteroaryl derivative having the formula (I). The compounds of the invention are considered useful for the treatment of affective disorders such as general anxiety disorder, panic disorder, obsessive compulsive disorder, depression, social phobia and eating disorders, and neurological disorders such as psychosis.
    Type: Application
    Filed: June 5, 2007
    Publication date: January 31, 2008
    Applicant: H. Lundbeck A/S
    Inventors: Mario Rottlander, Ejner Moltzen, Ivan Mikkelsen, Thomas Ruhland, Kim Andersen, Christian Krog-Jensen
  • Publication number: 20070173522
    Abstract: The invention provides compounds represented by the general formula (I) wherein the substituents are defined in the application. The compounds are useful in the treatment of an affective disorder, including depression, anxiety disorders including general anxiety disorder and panic disorder and obsessive compulsive disorder.
    Type: Application
    Filed: April 2, 2004
    Publication date: July 26, 2007
    Inventors: Ask Puschl, Benny Bang-Andersen, Morten Jorgensen, Karsten Juhl, Thomas Ruhland, Kim Andersen, Jan Kehler
  • Publication number: 20070060574
    Abstract: The invention provides compounds represented by the general formula I wherein the substituents are defined in the application. The compounds are useful in the treatment of an affective disorder, including depression, anxiety disorders including general anxiety disorder and panic disorder and obsessive compulsive disorder.
    Type: Application
    Filed: October 19, 2006
    Publication date: March 15, 2007
    Applicant: H. Lundbeck A/S
    Inventors: Thomas Ruhland, Garrick Smith, Benny Bang-Andersen, Ask Puschl, Ejner Moltzen, Kim Andersen
  • Publication number: 20060281746
    Abstract: The present invention relates to cyclopropyl derivatives of formula (I) and salt thereof. These compounds are NK3 receptor antagonists and may therefore be useful for treatment of diseases where the NK3 receptor is implicated, e.g. psychotic disorders.
    Type: Application
    Filed: August 13, 2004
    Publication date: December 14, 2006
    Inventors: Jan Kehler, Tore Hansen, Anders Poulsen, Berith Bjornholm, Thomas Ruhland, Morten Norgaard, Soren Nielsen
  • Patent number: 7148238
    Abstract: The invention provides compounds represented by the general formula I wherein the substituents are defined in the application. The compounds are useful in the treatment of an affective disorder, including depression, anxiety disorders including general anxiety disorder and panic disorder and obsessive compulsive disorder.
    Type: Grant
    Filed: December 6, 2005
    Date of Patent: December 12, 2006
    Assignee: H. Lundbeck A/S
    Inventors: Thomas Ruhland, Benny Bang-Andersen, Ask Puschl
  • Patent number: 7144884
    Abstract: The invention provides compounds represented by the general formula I wherein the substituents are defined in the application.
    Type: Grant
    Filed: October 2, 2002
    Date of Patent: December 5, 2006
    Assignee: H. Lundbeck A/S
    Inventors: Thomas Ruhland, Garrick Paul Smith, Benny Bang-Andersen, Ask Puschl, Ejner Knud Moltzen, Kim Andersen
  • Patent number: 7138407
    Abstract: The invention provides compounds represented by the general formula I wherein the substituents are defined in the application. The compounds are useful in the treatment of an affective disorder, including depression, anxiety disorders including general anxiety disorder and panic disorder and obsessive compulsive disorder.
    Type: Grant
    Filed: December 6, 2005
    Date of Patent: November 21, 2006
    Assignee: H. Lundbeck A/S
    Inventors: Thomas Ruhland, Garrick Paul Smith, Benny Bang-Andersen, Ask Puschl, Ejner Knud Moltzen, Kim Andersen
  • Patent number: 7067501
    Abstract: The invention provides compounds of the formula wherein the substituents are as defined in the application. The compounds are valuable glycine transport inhibitors.
    Type: Grant
    Filed: May 20, 2004
    Date of Patent: June 27, 2006
    Assignee: H. Lundbeck A/S
    Inventors: Garrick P. Smith, Gitte Mikkelsen, Kim Andersen, Daniel Greve, Thomas Ruhland, Stephen P. Wren
  • Publication number: 20060100242
    Abstract: The invention provides compounds represented by the general formula (I) wherein the substituents are defined in the application. The compounds are useful in the treatment of an affective disorder, including depression, anxiety disorders including general anxiety disorder and panic disorder and obsessive compulsive disorder.
    Type: Application
    Filed: April 2, 2004
    Publication date: May 11, 2006
    Applicant: H.Lundbeck A/S
    Inventors: Ask Puschl, Benny Bang-Andersen, Morten Jorgensen, Thomas Ruhland, Tine Stensbol
  • Publication number: 20060089368
    Abstract: The invention provides compounds represented by the general formula I wherein the substituents are defined in the application. The compounds are useful in the treatment of an affective disorder, including depression, anxiety disorders including general anxiety disorder and panic disorder and obsessive compulsive disorder.
    Type: Application
    Filed: December 6, 2005
    Publication date: April 27, 2006
    Applicant: H. Lundbeck A/S
    Inventors: Thomas Ruhland, Garrick Smith, Benny Bang-Andersen, Ask Puschl, Ejner Moltzen, Kim Andersen
  • Publication number: 20060084662
    Abstract: The invention provides compounds represented by the general formula I wherein the substituents are defined in the application. The compounds are useful in the treatment of an affective disorder, including depression, anxiety disorders including general anxiety disorder and panic disorder and obsessive compulsive disorder.
    Type: Application
    Filed: December 6, 2005
    Publication date: April 20, 2006
    Applicant: H. Lundbeck A/S
    Inventors: Thomas Ruhland, Garrick Smith, Benny Bang-Andersen, Ask Puschl, Ejner Moltzen, Kim Andersen
  • Publication number: 20050171061
    Abstract: The invention provides compounds of the formula wherein the substituents are as defined in the application. The compounds are valuable glycine transport inhibitors.
    Type: Application
    Filed: May 20, 2004
    Publication date: August 4, 2005
    Applicant: H. Lundbeck A/S
    Inventors: Garrick Smith, Gitte Mikkelsen, Kim Andersen, Daniel Greve, Thomas Ruhland, Stephen Wren
  • Publication number: 20050130228
    Abstract: A dosing form for a polymer support for organic chemical synthesis in a solvent medium comprising a fixed weight amount of beads of a polymer containing functional groups, which polymer is insoluble in the solvent for the intended synthesis, is provided as compressed tablets of essentially equal weight and composition wherein the polymer beads are essentially intact and are released as such when the tablets are disintegrated in said solvent. Use of the dosing form is made in conventional synthesis, in parallel synthesis, in split and mix synthesis and/or combinatorial chemistry. In a method for producing the dosing form, beads of a polymer having functional gropusgroups is compressed into tablets after pre-treatment with an aprotic organic solvent. groups are compressed into tablets after pre-treatment with an aprotic organic solvent.
    Type: Application
    Filed: October 14, 2004
    Publication date: June 16, 2005
    Applicant: H. Lundbeck A/S
    Inventors: Thomas Ruhland, Per Holm, Kirsten Schultz, Jannie Holm, Kim Andersen