Abstract: Certain aspects relate to drug delivery devices and methods for the treatment of ocular disorders requiring targeted and controlled administration of a drug to an interior portion of the eye. In several embodiments, the devices are capable of controlled release of two or more drugs, the release of each drug into a different ocular space (e.g., an ocular compartment versus an ocular fluid outflow pathway).

Abstract: Disclosed herein are drug delivery implants configured to be implanted into the eye of a subject and serve as intraocular drug depots. The implants reside in an intraocular target site until activation, at which time the implants release the drug (or drugs) housed within the implant in a controlled release fashion.

Abstract: A mooring system for mooring a turreted vessel off-shore, which comprises: line pulling equipment mounted in the vessel turret; a block located in the water at a depth below expected wave action and at a distance from the vessel; a mooring line extending from the puling equipment, through a fairlead at the bottom of the vessel turret, through the block and back for releasable attachment to the vessel; and mooring tackle attached to the block and extending away from the vessel to an anchor. The mooring line and mooring tackle form a catenary between the vessel and the anchor which has a curve adapted to maintain the anchor securely attached to the sea bottom, and to maintain the block below the depth of expected wave action.

Abstract: A mooring system for mooring a vessel off-shore, which comprises a block located in the water at a depth below expected wave action and at a distance from the vessel; a mooring line extending from line pulling equipment on the vessel, through the block and back, for releasable attachment to the vessel; mooring tackle attached to the block and extending away from the vessel to an anchor. The mooring line and mooring tackle form a catenary, between the vessel and the anchor, which has a curve adapted to maintain the anchor securely attached to the bottom and to maintain the block below the depth of expected wave action. Preferably, the mooring line passes from the pulling equipment through a fairlead located near the vessel's waterline, and then to the block.