Patents by Inventor Thomas S Moore
Thomas S Moore has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240148868Abstract: Provided herein are chimeric receptors, engineered cells and pharmaceutical compositions for enhancement of long-term clearance of protein aggregates in the central nervous system via phagocytosis or engulfment. Further provided herein are methods of treatment of subjects suffering from, or diagnosed with, a neurodegenerative disease by administering these receptors, modified cells, and/or pharmaceutical compositions. Administration of one or more, or a plurality of these modified cells, to a subject may provide treatment of a neurodegenerative disease such as Alzheimer's Disease (AD) or Parkinson's Disease (PD). Advantageously, the modified cells, pharmaceutical compositions, and methods of the present disclosure meet existing needs in the art by providing clearance of accumulations of protein aggregates in brain tissue in PD and AD pathologies.Type: ApplicationFiled: March 17, 2022Publication date: May 9, 2024Applicant: University of Florida Research Foundation, IncorporatedInventors: Todd Eliot Golde, Marshall S. Goodwin, Brenda Dawn Moore, Thomas B. Ladd, Yong Ran, Yona Levites, Pedro Cruz
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Patent number: 7300697Abstract: A reinforced polymer matrix composite material with anti-anisotropy reinforcement array is disclosed having coupled fiber reinforcement structures. The coupled fiber reinforcement structures are formed of a plurality of bound or bonded fibers, which form multi-dimensional structures capable of maintaining cross structure during molding. The structures are sized to allow their use in various molding processes. The coupled multiple fiber structures preferably have an aspect ratio of less than ten.Type: GrantFiled: August 5, 2004Date of Patent: November 27, 2007Assignee: Chrysler LLCInventors: Thomas S Moore, Gilbert B Chapman, II
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Patent number: 7231994Abstract: A hybrid vehicle includes an internal combustion engine coupled to a combined starter/motor/generator which is, in turn, coupled to a transmission of the vehicle. The starter/motor/generator is coupled to a high voltage battery pack via an inverter and to a deployable power output panel for serving loads external to the vehicle. Whenever external loads are to be powered, a control unit automatically places the vehicle in PARK, or alternatively activates an electrical parking brake system to hold the vehicle stationary.Type: GrantFiled: May 5, 2004Date of Patent: June 19, 2007Assignee: DaimlerChrysler CorporationInventors: Arthur J Buglione, Thomas S Moore, Gerald Cilibraise, Kathi S Lee, Richard G Reed, Jr., Del C Schroeder, Robert G Malcolm, Edmund Tworkowski, Kenneth Hartwig, Lewis Charles Eanes, Sr., Glenn E Lucas, Robert L Davis, William W Doolittle, III
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Patent number: 7198761Abstract: A hydrogen fuel system for a vehicle includes a fuel tank having a fuel inlet for receiving a borohydride fuel into a fuel holding portion of an internal cavity, and a waste inlet arranged to receive the waste liquid generated by an on-board hydrogen reaction process. The waste liquid is received into a waste liquid portion of the internal cavity. An expandable divider element is positioned within the tank to keep the fuel holding portion of the internal cavity separate from the waste liquid holding portion. The waste liquid holding portion can be positioned within the internal cavity so as to allow heat from the waste liquid to preheat the fuel stored in the fuel holding portion.Type: GrantFiled: December 10, 2002Date of Patent: April 3, 2007Assignee: DaimlerChrysler CorporationInventors: Jason W Buelow, Doanh Tran, Thomas S Moore, Mohsen D Shabana, Christopher E Borroni-Bird
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Patent number: 6929306Abstract: A rear seat assembly of a passenger cabin of a pick-up truck includes a rear seat cushion and a rear seat back, each rotatable such that a bottom surface of the rotated rear seat back can rest upon a rear end of the rotated seat cushion to provide a storage space beneath the rotated seat back and between the rotated seat cushion and a rear wall of the passenger cabin. The cargo bed of the truck may be extended into the storage space by providing an access door thereto in a front wall of the cargo bed in communication with a corresponding opening in the rear wall of the passenger cabin.Type: GrantFiled: September 16, 2004Date of Patent: August 16, 2005Assignee: DaimlerChrysler CorporationInventors: Kenneth S Mack, Thomas S Moore, Russell C Fielding
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Patent number: 6896313Abstract: A convertible cargo bed cover can function as both a tonneau cover and a cargo bed cap. The cover is raised by motorized elements to be substantially aligned with a roof of a passenger cabin of the vehicle. Side and rear window panels stored inside the cover can be installed to transform the cover to a cap to enlarge available enclosed cargo space. Rear pillars are installed at the rear corners of the tonneau cover in its raised position to complete the installation.Type: GrantFiled: September 16, 2004Date of Patent: May 24, 2005Assignee: DaimlerChrysler CorporationInventors: Kenneth S Mack, Thomas S Moore, Russell C Fielding
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Patent number: 6837531Abstract: A rear seat assembly of a passenger cabin of a pick-up truck includes a rear seat cushion and a rear seat back, each rotatable such that a bottom surface of the rotated rear seat back can rest upon a rear end of the rotated seat cushion to provide a storage space beneath the rotated seat back and between the rotated seat cushion and a rear wall of the passenger cabin. The cargo bed of the truck may be extended into the storage space by providing an access door thereto in a front wall of the cargo bed in communication with a corresponding opening in the rear wall of the passenger cabin.Type: GrantFiled: July 23, 2003Date of Patent: January 4, 2005Assignee: DaimlerChrysler CorporationInventors: Kenneth S Mack, Thomas S Moore, Russell C Fielding
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Patent number: 6830532Abstract: A method for controlling a powertrain in a motor vehicle having a first torque source and a second torque source each providing a torque output to a transmission includes determining a vehicle speed and a current gear selection of the motor vehicle. A threshold value is calculated from the vehicle speed and the current gear selection. An accelerator position of the motor vehicle is then determined. An accelerator position rate of change is calculated from the accelerator position. The accelerator position rate of change is compared to the threshold value. The torque output from the first torque source is increased if the accelerator position rate of change is less than the threshold value. However, the transmission is downshifted if the accelerator position rate of change is greater than the threshold value.Type: GrantFiled: July 30, 2003Date of Patent: December 14, 2004Assignee: DaimlerChrysler CorporationInventors: Brian P Gebby, Thomas S Moore, Gerald Cilibraise
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Patent number: 6820915Abstract: A convertible cargo bed cover can function as both a tonneau cover and a cargo bed cap. The cover is raised by motorized elements to be substantially aligned with a roof of a passenger cabin of the vehicle. Side and rear window panels stored inside the cover can be installed to transform the cover to a cap to enlarge available enclosed cargo space. Rear pillars are installed at the rear corners of the tonneau cover in its raised position to complete the installation.Type: GrantFiled: July 24, 2003Date of Patent: November 23, 2004Assignee: DaimlerChrysler CorporationInventors: Kenneth S Mack, Thomas S Moore, Russell C Fielding
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Patent number: 6810932Abstract: A seal within the filler neck of a fluid reservoir is configured to provide fluid channels into the reservior while in the at-rest position, but seals the filler neck when deformed by an externally directed insert in the filler neck. The seal is a hollow bulb with a frusto-conical surface spaced from a parallel frusto-conical surface of the filler neck by a plurality of ribs therebetween. The gap between the ribs, and between the surfaces of the seal and the filler neck, from fluid channels for replenishing the reservoir. A plunger inserted into the filler neck deflects the seal outwardly into contact with the filler neck, closing the fluid channels and preventing matter from entering the fluid reservoir.Type: GrantFiled: September 18, 2003Date of Patent: November 2, 2004Assignee: DaimlerChrysler CorporationInventors: David Corven, Grigory Yezersky, Thomas S Moore, Gerald Cilibraise, Edmund Tworkowski, William W Doolittle, III
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Publication number: 20040172943Abstract: A hydrogen fuel system for a vehicle includes a fuel tank having a fuel inlet for receiving a borohydride fuel into a fuel holding portion of an internal cavity, and a waste inlet arranged to receive the waste liquid generated by an on-board hydrogen reaction process. The waste liquid is received into a waste liquid portion of the internal cavity. An expandable divider element is positioned within the tank to keep the fuel holding portion of the internal cavity separate from the waste liquid holding portion. The waste liquid holding portion can be positioned within the internal cavity so as to allow heat from the waste liquid to preheat the fuel stored in the fuel holding portion.Type: ApplicationFiled: December 10, 2002Publication date: September 9, 2004Inventors: Jason W. Buelow, Doanh Tran, Thomas S. Moore, Mohsen D. Shabana, Christopher E. Borroni-Bird
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Publication number: 20040164578Abstract: A convertible cargo bed cover can function as both a tonneau cover and a cargo bed cap. The cover is raised by motorized elements to be substantially aligned with a roof of a passenger cabin of the vehicle. Side and rear window panels stored inside the cover can be installed to transform the cover to a cap to enlarge available enclosed cargo space. Rear pillars are installed at the rear corners of the tonneau cover in its raised position to complete the installation.Type: ApplicationFiled: July 24, 2003Publication date: August 26, 2004Inventors: Kenneth S. Mack, Thomas S. Moore, Russell C. Fielding
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Publication number: 20040138023Abstract: A dual displacement engine system is provided including a first crankshaft for providing driving torque to a transmission and a second crankshaft that can be utilized to supplement the driving torque of the first engine crankshaft to meet higher torque demand requirements. An overrunning clutch device is provided for introducing the torque provided by the secondary engine crankshaft.Type: ApplicationFiled: January 9, 2003Publication date: July 15, 2004Inventors: Thomas S. Moore, Brian P. Gebby
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Publication number: 20040130175Abstract: A rear seat assembly of a passenger cabin of a pick-up truck includes a rear seat cushion and a rear seat back, each rotatable such that a bottom surface of the rotated rear seat back can rest upon a rear end of the rotated seat cushion to provide a storage space beneath the rotated seat back and between the rotated seat cushion and a rear wall of the passenger cabin. The cargo bed of the truck may be extended into the storage space by providing an access door thereto in a front wall of the cargo bed in communication with a corresponding opening in the rear wall of the passenger cabin.Type: ApplicationFiled: July 23, 2003Publication date: July 8, 2004Inventors: Kenneth S. Mack, Thomas S. Moore, Russell C. Fielding
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Publication number: 20040091690Abstract: A reinforced polymer matrix composite material with an anti-anisotropy reinforcement array is disclosed having three dimensional fiber reinforcement structures. The fiber reinforcement structures are formed of a plurality of bound or bonded fibers, which form multi-dimensional structures capable of maintaining cross structure during molding. The structures are sized to allow their use in various molding processes.Type: ApplicationFiled: November 12, 2002Publication date: May 13, 2004Inventors: Thomas S. Moore, Gilbert B. Chapman, Del C. Schroeder
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Patent number: 6691754Abstract: The present invention couples a tire pump with the wheel rim of a vehicle. The pump is activated electromagnetically to inflate the tire as desired, e.g. when tire pressure is below a required value. The pump is arranged to draw air from the atmosphere and pump into an interior portion of the tire. A magnetized plunger within the pump is biased to an initial position by a biasing element. Energizing an electromagnet generates a magnetic field. The pump is arranged to rotate in and out of the magnetic field to cause the plunger to reciprocate and inflate the tire.Type: GrantFiled: July 24, 2002Date of Patent: February 17, 2004Assignee: DaimlerChrysler CorporationInventor: Thomas S. Moore
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Publication number: 20040016492Abstract: The present invention couples a tire pump with the wheel rim of a vehicle. The pump is activated electromagnetically to inflate the tire as desired, e.g. when tire pressure is below a required value. The pump is arranged to draw air from the atmosphere and pump into an interior portion of the tire. A magnetized plunger within the pump is biased to an initial position by a biasing element. Energizing an electromagnet generates a magnetic field. The pump is arranged to rotate in and out of the magnetic field to cause the plunger to reciprocate and inflate the tire.Type: ApplicationFiled: July 24, 2002Publication date: January 29, 2004Inventor: Thomas S. Moore
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Patent number: 6605390Abstract: A lithium ion battery (200) has at least two carbon foam electrodes (54, 56). Each of the electrodes (54, 56) is fitted with a plate (60, 62 respectively) formed from an electrically conductive material. The plate (60, 62) has an underside which is formed so as to be attached to one end of the carbon foam electrode (54, 56). The plate (60, 62) may be fixed to the electrode by crimping or a similar deforming process or may be fitted thereto by an electrically conductive adhesive.Type: GrantFiled: August 8, 2001Date of Patent: August 12, 2003Assignee: DaimlerChrysler CorporationInventors: Thomas S Moore, Subimal Dinda
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Publication number: 20030072933Abstract: A reinforced polymer matrix composite material with anti-anisotropy reinforcement array is disclosed having coupled fiber reinforcement structures. The coupled fiber reinforcement structures are formed of a plurality of bound or bonded fibers, which form multi-dimensional structures capable of maintaining cross structure during molding. The structures are sized to allow their use in various molding processes. The coupled multiple fiber structures preferably have an aspect ratio of less than ten.Type: ApplicationFiled: October 11, 2001Publication date: April 17, 2003Inventors: Thomas S. Moore, Gilbert B. Chapman
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Patent number: RE38400Abstract: A lift type tailgate on a passenger van type vehicle body is operated by an electric motor powered actuator with an electronic control circuit utilizing a microprocessor operating under program control to respond to user-initiated opening and closing signals to move the tailgate in the selected direction. In the control circuit, feedback information to the microprocessor indicative of tailgate position is provided by a potentiometer coupled with the actuator motor and the microprocessor is programmed to operate with this information to stop the tailgate at a wide open position, a partially closed position and a fully closed position. Obstruction detection is performed by the microprocessor using an obstruction detection circuit and additionally by monitoring the position signal input from the potentiometer to stop the tailgate on encountering an obstacle.Type: GrantFiled: December 15, 1997Date of Patent: January 27, 2004Assignee: DaimlerChrysler CorporationInventors: David J. Kowall, Delbert D. DeRees, Thomas S. Moore, David R. Bernier