Abstract: Provided are methods for assessing T cell receptor ? chain complementary determining region 3 (TCR? CDR3) sequences. In certain embodiments, prior to the assessing, the subject has been identified as having, or is suspected of having, inflammatory bowel disease (IBD). According to some embodiments, at the time of the assessing, the subject has one or more non-specific symptoms consistent with Crohn's disease. Also provided are methods comprising administering a Crohn's disease therapy to a subject identified as comprising T cells that express a T cell receptor ? chain (TCR?) comprising a TCR? CDR3 sequence set forth in the present disclosure. Computer readable media and systems for assessing TCR? CDR3 sequences are also provided.

Abstract: A system and method for illuminating hot air balloons is claimed. The system includes a activating a burner assembly on multiple hot air balloons from a central location. As the burner assemblies are activated, the hot air balloons become illuminated. Consequently, the illumination of multiple hot air balloons can be synchronized and otherwise choreographed from a single control station.

Abstract: In the embodiment depicted and described, the invention comprises a retainer for a sphere, having a sphere captive therein, replaceably attached to the reverse side of a picture frame to cause the frame, automatically, to assume a plumb disposition. The sphere, a round ball, is movable within a track formed in the retainer, and a portion thereof projects from the track for rolling engagement with the surface of a wall from which the frame is suspended. In use, a pair of the ball-retainers are fixed to the reverse side of the frame, at spaced apart locations, with the tracks lying substantially along arcs drawn from a suspension point on the frame which intersects the frame center of gravity.