Abstract: Described are methods and systems for determining modal patterns from an overall trend, minor trend or significant trend for various periods during a time of the day modal report which can be utilized to provide insights to the person with diabetes.

Abstract: Described are methods and systems for determining clusters of glucose data that can be utilized to provide insights to the person with diabetes, such as, for example, when a certain number of measurements during a predetermined time period is less than a predetermined threshold so that the subject is notified that the number of glucose measurements is less than optimum for management of diabetes.

Abstract: Described are methods and systems for determining clusters of glucose data that can be utilized to provide insights to the person with diabetes, such as, for example, when a certain number of measurements during a predetermined time period is less than a predetermined threshold so that the subject is notified that the number of glucose measurements is less than optimum for management of diabetes.

Abstract: Described and illustrated is a system for management of diabetes that includes an infusion pump, glucose sensor and controller with a method programmed in the controller. The infusion pump is configured to deliver insulin. The glucose sensor senses glucose levels in the subject and provide output signals representative of the glucose levels in the subject. The controller is programmed receives signals from at least one of the glucose sensor and the pump and configured to issue signals to the pump to deliver an amount of insulin determined by a feedback controller that utilizes a model predictive control based on desired glucose levels, insulin amount delivered and measured glucose levels of the subject. The controller is also configured to deliver insulin using a tuning factor (R) for a model predictive controller in the microcontroller as a conservative setting otherwise the system maintains a current tuning factor (R) for the controller.

Abstract: A decision support system includes a measurement device configured to continuously measure a physiological parameter of a patient. An insulin delivery device provides insulin to the patient per an initial basal profile and the parameter measurements. A storage device holds historical data of insulin delivery to the patient. A processor determines deviations of the delivery of insulin from the basal profile for one or more time period(s) using the historical data, computes a respective first basal-profile adjustment for each of the one or more time period(s) using the determined deviations, and annunciates the computed first basal-profile adjustment(s). A method of recommending a basal-rate adjustment includes measuring the parameter, infusing the patient with insulin and storing the historical data, determining the deviations from the basal profile, computing the first basal-profile adjustments, and annunciating the computed first basal-profile adjustment(s).

Abstract: Described and illustrated is a system for management of diabetes that includes an infusion pump, glucose sensor and controller with a method programmed in the controller. The infusion pump is configured to deliver insulin. The glucose sensor senses glucose levels in the subject and provide output signals representative of the glucose levels in the subject. The controller is programmed receives signals from at least one of the glucose sensor and the pump and configured to issue signals to the pump to deliver an amount of insulin determined by a feedback controller that utilizes a model predictive control based on desired glucose levels, insulin amount delivered and measured glucose levels of the subject. The controller is also configured to deliver insulin using a tuning factor (R) for a model predictive controller in the microcontroller as a conservative setting otherwise the system maintains a current tuning factor (R) for the controller.

Abstract: Described are methods and systems for determining modal patterns from an overall trend, minor trend or significant trend for various periods during a time of the day modal report which can be utilized to provide insights to the person with diabetes.

Abstract: Described are methods and systems for determining clusters of glucose data that can be utilized to provide insights to the person with diabetes, such as, for example, when a certain number of measurements during a predetermined time period is less than a predetermined threshold so that the subject is notified that the number of glucose measurements is less than optimum for management of diabetes.

Abstract: Described are methods and systems to annunciate to the patient of the components involved in each of the daily risk range based on the glucose measurements to assist the patient in identification of whether it is hypoglycemia or hyperglycemia are driving the daily risk range of the measured glucose values.

Abstract: A computer-implemented method and system of distributing medical information in real time populates a network database with information on disease indications and on therapeutic products, such as natural history of disease and benefit-risk considerations; categorizes the information; displays the information and notifies of the categorization of information.

Abstract: Proposed is a method for the dewatering of a material layer (S) of paper fibers in a double-screen former, where the sheet weight (oven dried sheet weight (otro)) is more than 100 g/m.sup.2 and/or the screen circulates with a speed of at least 100 m/min. In accordance with the invention the two screens are guided at two guide surfaces (5 and 7) which, for example, belong to open forming cylinders. In this arrangement forming cylinders of this kind are so dimensioned and positioned that no dewatering elements which contact one of the screens are present between the run-out line (11) of the screens (2, 3) from the first guide surface and the run-in line (12) at the second guide surface.

Abstract: The wet section of a twin wire papermaking machine is provided with an open forming roll at the lower wire and with the combination of a suction box at the lower wire and a vacuum suction box at the upper wire. Furthermore, by selecting the elevational position or level of the individual wire sections there can be obtained particularly advantageous conditions for the operation of the papermaking machine throughout a wide field of application, especially heavy types of paper at relatively low operating velocities of the papermaking machine. Gap-former and hybrid-former constructions of the papermaking machine are possible.