Patents by Inventor Thomas Schlaubitz
Thomas Schlaubitz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230258676Abstract: A method for introducing a sample rack holding a plurality of sample receptacles into a receiving bay in a housing of an automated analytical system is disclosed. The method is carried out by manually moving the sample rack from a loading position towards a processing position along a lane in the receiving bay, pausing the movement when the rack reaches a focusing position, moving a reader to focuse onto the lane, resuming the movement of the sample rack and detecting features of the sample rack during the movement, positioning, detecting, and locking the sample rack in the processing position, and processing the content of the sample receptacles.Type: ApplicationFiled: November 17, 2022Publication date: August 17, 2023Inventors: Fabian Baggio, Roman Egli, Christian Ettel, Raphael Gut, Pius Hermann, Nikifor Korjagin, Alexander Meier, Thomas Schlaubitz, Rolf Schneebeli, Simon Siegenthaler, Ivo Daniel Vicente Leitao, Stefan Vollenweider
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Patent number: 11638920Abstract: The present invention relates to the field of high throughput analysis of samples. In particular, the present invention is directed to a device, a System and a method for simultaneous tempering of multiple samples. More particular, the invention relates to the simultaneous thermocycling of multiple samples to perform PCR in a microtiter plate format.Type: GrantFiled: February 16, 2022Date of Patent: May 2, 2023Assignee: Roche Molecular Systems, Inc.Inventors: Thomas Schlaubitz, Torsten Burdack, Paul Federer, Christian George, Guido Grueter, Andreas Scholle, Guenter Tenzler
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Publication number: 20220168744Abstract: The present invention relates to the field of high throughput analysis of samples. In particular, the present invention is directed to a device, a System and a method for simultaneous tempering of multiple samples. More particular, the invention relates to the simultaneous thermocycling of multiple samples to perform PCR in a microtiter plate format.Type: ApplicationFiled: February 16, 2022Publication date: June 2, 2022Applicant: Roche Molecular Systems, Inc.Inventors: Thomas Schlaubitz, Torsten Burdack, Paul Federer, Christian George, Guido Grueter, Andreas Scholle, Guenter Tenzler
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Patent number: 11285488Abstract: The present invention relates to the field of high throughput analysis of samples. In particular, the present invention is directed to a device, a System and a method for simultaneous tempering of multiple samples. More particular, the invention relates to the simultaneous thermocycling of multiple samples to perform PCR in a microtiter plate format.Type: GrantFiled: August 8, 2018Date of Patent: March 29, 2022Assignee: Roche Molecular Systems, Inc.Inventors: Thomas Schlaubitz, Torsten Burdack, Paul Federer, Christian George, Guido Grueter, Andreas Scholle, Guenter Tenzler
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Patent number: 10884006Abstract: A heating device for heating a thermally fixable sealing cover disposed over the microplate adjacent the wells, a cooling device for actively cooling the microplate and a controller set up to control activity of the heating and cooling devices in a manner to heat the sealing cover so as to thermally fix it to the microplate and to actively cool the microplate so as to keep a temperature of the samples below a predefined temperature when heating the sealing cover. It further relates to a method for automatically sealing a microplate in which the thermally fusible sealing cover is disposed over the microplate, the sealing cover is heated to thermally fix it to the microplate and the microplate is actively cooled in a manner that a temperature of the liquid reaction mixtures is kept below a predefined temperature when heating the sealing cover.Type: GrantFiled: January 24, 2018Date of Patent: January 5, 2021Assignee: Roche Molecular Systems, Inc.Inventors: Daniel Bommer, Thomas Schlaubitz, Pius Studer
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Publication number: 20190070611Abstract: The present invention relates to the field of high throughput analysis of samples. In particular, the present invention is directed to a device, a System and a method for simultaneous tempering of multiple samples. More particular, the invention relates to the simultaneous thermocycling of multiple samples to perform PCR in a microtiter plate format.Type: ApplicationFiled: August 8, 2018Publication date: March 7, 2019Inventors: Thomas Schlaubitz, Torsten Burdack, Paul Federer, Christian George, Guido Grueter, Andreas Scholle, Guenter Tenzler
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Patent number: 10183296Abstract: An assembly comprising a sample block, a heat sink and at least one electrodeposited thermoelectric element is disclosed. Further, an instrument and a method for performing a temperature-dependent reaction are disclosed.Type: GrantFiled: August 31, 2017Date of Patent: January 22, 2019Assignee: Roche Molecular Systems, Inc.Inventors: Sven Ebert, Paul Federer, Thomas Schlaubitz, Stefan Vollenweider, Urs Wittenwiler
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Publication number: 20180149668Abstract: A heating device for heating a thermally fixable sealing cover disposed over the microplate adjacent the wells, a cooling device for actively cooling the microplate and a controller set up to control activity of the heating and cooling devices in a manner to heat the sealing cover so as to thermally fix it to the microplate and to actively cool the microplate so as to keep a temperature of the samples below a predefined temperature when heating the sealing cover. It further relates to a method for automatically sealing a microplate in which the thermally fusible sealing cover is disposed over the microplate, the sealing cover is heated to thermally fix it to the microplate and the microplate is actively cooled in a manner that a temperature of the liquid reaction mixtures is kept below a predefined temperature when heating the sealing cover.Type: ApplicationFiled: January 24, 2018Publication date: May 31, 2018Applicant: Roche Molecular Systems, Inc.Inventors: Daniel Bommer, Thomas Schlaubitz, Pius Studer
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Publication number: 20180056297Abstract: An assembly (10) comprising a sample block (12), a heat sink (30) and at least one electrodeposited thermoelectric element (48) is disclosed. Further, an instrument and a method for performing a temperature-dependent reaction are disclosed.Type: ApplicationFiled: August 31, 2017Publication date: March 1, 2018Applicant: Roche Molecular System, Inc.Inventors: Sven Ebert, Paul Federer, Thomas Schlaubitz, Stefan Vollenweider, Urs Wittenwiler
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Patent number: 9903880Abstract: A heating device for heating a thermally fixable sealing cover disposed over the microplate adjacent the wells, a cooling device for actively cooling the microplate and a controller set up to control activity of the heating and cooling devices in a manner to heat the sealing cover so as to thermally fix it to the microplate and to actively cool the microplate so as to keep a temperature of the samples below a predefined temperature when heating the sealing cover. It further relates to a method for automatically sealing a microplate in which the thermally fusible sealing cover is disposed over the microplate, the sealing cover is heated to thermally fix it to the microplate and the microplate is actively cooled in a manner that a temperature of the liquid reaction mixtures is kept below a predefined temperature when heating the sealing cover.Type: GrantFiled: November 1, 2011Date of Patent: February 27, 2018Assignee: Roche Molecular Systems, Inc.Inventors: Daniel Bommer, Thomas Schlaubitz, Pius Studer
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Patent number: 9365895Abstract: An automated nucleic acid analysis method and analytical system are described comprising separate modules, wherein the air flow of any one of said modules is controlled and wherein at least the air flow between the module for isolation and purification of the analyte and the module for analysis of the analyte are separated.Type: GrantFiled: August 8, 2013Date of Patent: June 14, 2016Assignee: Roche Molecular Systems, Inc.Inventors: Roland Bernet, Andreas Gisler, Marcel Kaeppeli, Raymond Ochsenbein, Thomas Schlaubitz
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Patent number: 8809039Abstract: An automated nucleic acid analysis method and analytical system are described comprising separate modules, wherein the air flow of any one of said modules is controlled and wherein at least the air flow between the module for isolation and purification of the analyte and the module for analysis of the analyte are separated.Type: GrantFiled: August 8, 2013Date of Patent: August 19, 2014Assignee: Roche Molecular Systems, Inc.Inventors: Roland Bernet, Andreas Gisler, Marcel Kaeppeli, Raymond Ochsenbein, Thomas Schlaubitz
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Publication number: 20130323741Abstract: An automated nucleic acid analysis method and analytical system are described comprising separate modules, wherein the air flow of any one of said modules is controlled and wherein at least the air flow between the module for isolation and purification of the analyte and the module for analysis of the analyte are separated.Type: ApplicationFiled: August 8, 2013Publication date: December 5, 2013Applicant: Roche Molecular Systems, Inc.Inventors: Roland Bernet, Andreas Gisler, Marcel Kaeppeli, Raymond Ochsenbein, Thomas Schlaubitz
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Publication number: 20130323826Abstract: An automated nucleic acid analysis method and analytical system are described comprising separate modules, wherein the air flow of any one of said modules is controlled and wherein at least the air flow between the module for isolation and purification of the analyte and the module for analysis of the analyte are separated.Type: ApplicationFiled: August 8, 2013Publication date: December 5, 2013Applicant: Roche Molecular Systems, Inc.Inventors: Roland Bernet, Andreas Gisler, Marcel Kaeppeli, Raymond Ochsenbein, Thomas Schlaubitz
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Patent number: 8530229Abstract: An automated nucleic acid analysis method and analytical system are described comprising separate modules, wherein the air flow of any one of said modules is controlled and wherein at least the air flow between the module for isolation and purification of the analyte and the module for analysis of the analyte are separated.Type: GrantFiled: December 9, 2010Date of Patent: September 10, 2013Assignee: Roche Molecular Systems, Inc.Inventors: Raymond Ochsenbein, Andreas Gisler, Marcel Kaeppeli, Roland Bernet, Thomas Schlaubitz
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Publication number: 20120288923Abstract: A heating device for heating a thermally fixable sealing cover disposed over the microplate adjacent the wells, a cooling device for actively cooling the microplate and a controller set up to control activity of the heating and cooling devices in a manner to heat the sealing cover so as to thermally fix it to the microplate and to actively cool the microplate so as to keep a temperature of the samples below a predefined temperature when heating the sealing cover. It further relates to a method for automatically sealing a microplate in which the thermally fusible sealing cover is disposed over the microplate, the sealing cover is heated to thermally fix it to the microplate and the microplate is actively cooled in a manner that a temperature of the liquid reaction mixtures is kept below a predefined temperature when heating the sealing cover.Type: ApplicationFiled: November 1, 2011Publication date: November 15, 2012Applicant: Roche Molecular Systems, Inc.Inventors: Daniel Bommer, Thomas Schlaubitz, Pius Studer
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Patent number: 8271230Abstract: Disclosed herein are methods for monitoring a thermoelectric heating and cooling device (103, 203, 303) of a system (100, 200, 300) for cycling liquid reaction mixtures through a series of temperature excursions, and such systems adapted to perform these methods. A first quantity being either an electric current or an electric voltage is applied to the heating and cooling device (103, 203) or a portion (314) thereof (303), and a second quantity being either the non-selected first quantity or temperature is measured to obtain a first test value. The selected first quantity is applied to another thermoelectric heating and cooling device (104, 204) or another portion (315) of the first device (303), and the second quantity is measured to obtain a second test value. Comparison of the first and second test values yields a monitoring value which is compared with a pre-defined threshold value to obtain a monitoring result.Type: GrantFiled: December 15, 2009Date of Patent: September 18, 2012Assignee: Roche Molecular Systems, Inc.Inventors: Paul Federer, Daniel Bommer, Guido Grueter, Stefan Job, Thomas Schlaubitz
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Patent number: 8110396Abstract: The invention relates to a thermocycler module for heating and/or cooling of a thermocycling device comprising a thermal switch, a heating block and a heat sink. The thermal switch comprises a thermoconducting liquid, e.g. a magnetic fluid or a liquid metal, and a stimulating unit, e.g. a magnetic unit or a Lorentz-force unit, for moving the thermoconducting liquid. The movement of the thermoconducting liquid provides, in an on-state of the thermal switch, a thermal connection between the heating block and the heat sink.Type: GrantFiled: May 18, 2009Date of Patent: February 7, 2012Assignee: Roche Molecular Systems, Inc.Inventors: Daniel Bommer, Thomas Schlaubitz
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Publication number: 20110306053Abstract: An automated nucleic acid analysis method and analytical system are described comprising separate modules, wherein the air flow of any one of said modules is controlled and wherein at least the air flow between the module for isolation and purification of the analyte and the module for analysis of the analyte are separated.Type: ApplicationFiled: December 9, 2010Publication date: December 15, 2011Applicant: ROCHE MOLECULAR SYSTEMS, INC.Inventors: Raymond Ochsenbein, Andreas Gisler, Marcel Kaeppeli, Roland Bernet, Thomas Schlaubitz
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Patent number: 8017094Abstract: A rack for holding containers containing liquids used in clinical chemistry analyzers. The rack comprises (a) a frame having two or more sections, each section being adapted for receiving a liquid containing component, at least one of the sections of the frame being adapted for receiving a first liquid containing component which is adapted for being removably but tightly mechanically connected to said frame, (b) at least one movable part adapted to be removably coupled to a shaker device, the movable part being adapted for receiving and holding a second liquid containing component, at least one of the sections of the frame being adapted for receiving the movable part and allowing motion of the movable part within predetermined limits.Type: GrantFiled: October 14, 2005Date of Patent: September 13, 2011Assignee: Roche Molecular Systems, Inc.Inventors: Thomas Meyer, Reto Schorno, Thomas Schlaubitz