Abstract: Anti-BK virus antibody molecules or binding fragments thereof are disclosed. These Anti-BK virus antibody molecules or binding fragments can be used in the treatment or prevention of BK virus infection and/or BK virus associated disorder.

Abstract: With the aid of one or more optical sensors, substrates which are faulty or have been incorrectly inserted in a CVD reactor are identified. The one or more optical sensors sense properties of the surfaces of the substrates, for example layer thickness or temperature, before or during a treatment process of the substrates within the CVD reactor housing. The measurement values provided by the sensors can be plotted in the form of a measurement curve, and patterns are obtained from the measurement curve, each pattern corresponding to one of the substrates. The patterns are compared with each other or with a mean calculated from the patterns.

Abstract: A medical device having a time-controlled start function and a control unit, which enables user-friendly operation of the medical device, is described. The medical device has a control unit, which is equipped for automatic start-up of the medical device at a predetermined point in time and for checking on whether, after start-up of the medical device, a predetermined event has occurred, and has a display screen for display of information when the check reveals that the event has not occurred. Furthermore, a corresponding process for user-friendly operation is described.

Abstract: The invention relates to an apparatus for disinfecting, in particular sterilizing, objects or solids, preferably pieces of protective equipment, in particular protective masks or protective clothing, with a treatment chamber for receiving one or more objects or solids, preferably one or more pieces of protective equipment, with a closable airlock through which objects or solids, preferably pieces of protective equipment, can be introduced into the treatment chamber and/or removed from the treatment chamber and with a generation unit for generating reactive species in a gas stream. The generation unit includes discharge means configured to generate an electrical discharge in the gas stream. The generating unit is arranged such that the gas stream, during operation, passes from the generating unit into the treatment chamber. The invention further relates to a use of the apparatus.

Abstract: A medical device having a time-controlled start function and a control unit, which enables user-friendly operation of the medical device, is described. The medical device has a control unit, which is equipped for automatic start-up of the medical device at a predetermined point in time and for checking on whether, after start-up of the medical device, a predetermined event has occurred, and has a display screen for display of information when the check reveals that the event has not occurred. Furthermore, a corresponding process for user-friendly operation is described.

Abstract: Disclosed are various embodiments for image-based verification of checklist items. In one embodiment, a user request is received to record a temperature reading of a food item using a handheld temperature sensor. In response to the user request, the temperature reading is received and an image of the handheld temperature sensor is captured. The image of the handheld temperature sensor is stored in association with the temperature reading.

Abstract: The invention concerns an ophthalmic lens having an increased resistance to thermal and hygroscopic stresses, said ophthalmic lens comprising a substrate, at least one main face of which is coated with a siloxane-based anti-abrasion hardcoat, characterized in that said ophthalmic lens further comprises at least one protective layer of an organic-inorganic material directly in contact with said hardcoat, said protective layer of organic-inorganic material having a Young's modulus higher than 20 GPa, preferably of at least 25 GPa.

Abstract: An X-ray device for carrying out X-ray scans is configured for a simplified procedure. The X-ray device has an image receptor which operates in conjunction with an X-ray generator to carry out X-ray scans of a patient, and a patient table. A tabletop of the patient table which is used to position the patient during the X-ray scans, is immovable in the table plane. Instead, the image receptor is disposed in a longitudinally and transversely movable manner relative to the tabletop parallel to the table plane.

Abstract: The invention relates to a circuit arrangement for a protective-conductor connection to at least two fluid-conducting lines 11, 12, in particular to at least two fluid-conducting lines which are guided outwards from the interior of a housing 1 of a medico-technical device, in particular the housing of a blood treatment device. The circuit arrangement comprises a plurality of protection apparatuses 16A, 16B; 17A, 17B for electrical contacting which are designed such that an electrical connection to a fluid in the line can be produced using each protection apparatus for electrical contacting. In the circuit arrangement, at least two protection apparatuses 16A, 16B; 17A, 17B for electrical contacting are assigned to each fluid-conducting line 11, 12. As a result, two protective measures are taken for each fluid-conducting line.

Abstract: During a process involving one or more process steps of a process phase, in which a substrate is located in the process chamber of a CVD reactor, a process temperature and a pressure are each set and a process gas flow is fed into the process chamber by way of control data delivered by a controller in accordance with a formula stored in the controller. Additionally, sensors are used to determine measurement data from which a current fingerprint is calculated and then compared with a historic fingerprint. The fingerprint includes only values or groups of values that are obtained from measured values that are recorded during one or more conditioning steps of a conditioning phase in which a conditioning temperature and a conditioning pressure are each set and a conditioning gas flow is fed into the process chamber in accordance with control data specified by the formula.

Abstract: A fixation device for fixing a contact element within a connector. The device includes a housing defining a contact element receptacle for receiving a contact element and a support face defining a deflection surface for supporting the contact element within the housing, and a clamping device for clamping the contact element in the contact element receptacle with a clamping force directed in a clamping direction. The deflection surface is oriented at an angle relative to the clamping direction such that it deflects a component or portion of the clamping force acting upon the contact element in a direction transverse to the clamping direction.

Abstract: The present disclosure provides TCRs with high or enhanced affinity against various tumor associated antigens (including human MAGE-A1 epitopes), T cells expressing such high affinity antigen-specific TCRs, nucleic acids encoding the same, and compositions for use in treating diseases or disorders in which cells overexpress one or more of these antigens, such as in cancer.

Abstract: The present disclosure provides binding proteins and TCRs with high affinity and specificity against Merkel cell polyomavirus T antigen epitopes or peptides, T cells expressing such high affinity Merkel cell polyomavirus T antigen specific TCRs, nucleic acids encoding the same, and compositions for use in treating Merkel cell carcinoma.

Abstract: A medical device having a time-controlled start function and a control unit, which enables user-friendly operation of the medical device, is described. The medical device has a control unit, which is equipped for automatic start-up of the medical device at a predetermined point in time and for checking on whether, after start-up of the medical device, a predetermined event has occurred, and has a display screen for display of information when the check reveals that the event has not occurred. Furthermore, a corresponding process for user-friendly operation is described.

Abstract: The invention relates to a circuit arrangement for a protective-conductor connection to at least two fluid-conducting lines 11, 12, in particular to at least two fluid-conducting lines which are guided outwards from the interior of a housing 1 of a medico-technical device, in particular the housing of a blood treatment device. The circuit arrangement comprises a plurality of protection apparatuses 16A, 16B; 17A, 17B for electrical contacting which are designed such that an electrical connection to a fluid in the line can be produced using each protection apparatus for electrical contacting. In the circuit arrangement, at least two protection apparatuses 16A, 16B; 17A, 17B for electrical contacting are assigned to each fluid-conducting line 11, 12. As a result, two protective measures are taken for each fluid-conducting line.

Abstract: The present disclosure provides TCRs with high or enhanced affinity against various tumor associated antigens (including human MAGE-A1 epitopes), T cells expressing such high affinity antigen-specific TCRs, nucleic acids encoding the same, and compositions for use in treating diseases or disorders in which cells overexpress one or more of these antigens, such as in cancer.

Abstract: Information is communicated to a process control device by performing a process that includes the step of heating a component, the component having structured volumetric regions. When the component is heated, structures present in the volumetric regions radiate in the infrared spectrum, allowing the structures to be distinguished by an infrared sensor. The structures, formed by elevations or depressions, form a machine-readable identifier, which can be used as an originality identification means for the component. Since the identifier can be determined in situ during a heating process, the process control device can recognize whether correction values are to be used for the thermal treatment of a substrate.

Abstract: An article has a cavity defined by an inner surface, the cavity having a size such that a largest sphere placeable in the cavity has a diameter of less than 7 cm and a smallest sphere placeable in the cavity has a diameter of 0.5 mm; and a hard coating on the inner surface, the hard coating having a hardness between 18 to 100 GPa, the hard coating distributed on the inner surface such that a ratio of a coating thickness at a first region of the hard coating to that at a second region of the hard coating ranges from 0.75 to 1.33.

Abstract: A method for producing one or more bearing components along a production line, comprising honing the bearing components along the production line, cleaning the bearing components along the production line, grinding the bearing components along the production line, and transporting the bearing components along the production line utilizing one or more transport units.

Abstract: A first x-ray image is acquired at a predetermined position of a focal point and with a first orientation of an x-ray tube of an x-ray device. Subsequently, the x-ray tube is adjusted by rotating about a predetermined angle and by positioning, wherein the focal point is situated in the predetermined position prior to the adjustment and after the adjustment. After the adjustment, the x-ray tube is situated in a second orientation. Subsequently, a second x-ray image is acquired at the predetermined position and with the second orientation. A combined x-ray image from at least the first and second x-ray image is produced.