Abstract: The Rubella Virus Spike construct comprises at least one E1 component and one E2 component, which are linked together. The E1 component consists of the El envelope protein, whose C-terminal transmembrane region and intravirional domain are removed and whose N-terminus comprises the ectodomain of the El envelope protein. The E2 component consists of the E2 envelope protein whose transmembrane regions and intravirional domain removed and whose C-terminus comprising the ectodomain of the E2 envelope protein. The C-terminus of the E2 component is connected to the N-terminus of the E1 component by direct fusion or by means of a linker to form an E1-E2 fusion protein.

Abstract: Processes for depositing functionalized nanoparticles upon a non-conductive substrate are disclosed herein. The processes may include the step of aerosolizing one or more particles into suspension within a gas, each of the one or more particles comprising functionalized nanoparticles having an electric charge. The processes may include the step the step of attracting the one or more particles onto a non-conductive substrate by a static electric charge opposite of the electric charge, wherein at least portions of the non-conductive substrate are having the static electric charge.

Abstract: In various aspects, the sensors include a substrate that is porous and non-conductive with nanoparticles deposited onto the substrate within pores of the substrate by an electrophoretic process to form a sensor element. The nanoparticles are electrically conductive. The sensor includes a detector in communication with the sensor element to measure a change in an electrical property of the sensor element. The change in the electrical property may result from alterations in quantum tunneling between nanoparticles within the sensor element, in various aspects.

Abstract: The Rubella Virus Spike construct comprises at least one E1 component and one E2 component, which are linked together. The E1 component consists of the E1 envelope protein, whose C-terminal transmembrane region and intravirional domain are removed and whose N-terminus comprises the ectodomain of the E1 envelope protein. The E2 component consists of the E2 envelope protein whose transmembrane regions and intravirional domain removed and whose C-terminus comprising the ectodomain of the E2 envelope protein. The C-terminus of the E2 component is connected to the N-terminus of the E1 component by direct fusion or by means of a linker to form an E1-E2 fusion protein.

Abstract: The present invention refers to a container precursor, comprising a composite sheet which comprises a) an outer polymer layer, b) a colour application, c) a carrier layer, and d) a barrier layer; wherein a wall of the container precursor comprises a first wall region and a second wall region. The invention further refers to a closed container, obtainable from the container precursor; and to a closed container having the above composite sheet, the first and the second wall region.

Abstract: In various aspects, the sensors include a substrate that is porous and non-conductive with nanoparticles deposited onto the substrate within pores of the substrate by an electrophoretic process to form a sensor element. The nanoparticles are electrically conductive. The sensor includes a detector in communication with the sensor element to measure a change in an electrical property of the sensor element. The change in the electrical property may result from alterations in quantum tunneling between nanoparticles within the sensor element, in various aspects.

Abstract: A cylinder-head gasket with a metal sealing layer (10) in which there are provided at least one combustion-chamber opening (B), screw holes around said opening for cylinder-head screws, and a combustion-chamber sealing bead (16) stamped into the sealing layer, wherein the combustion-chamber sealing bead has, on its convex side, a crest portion (30a?) which lies between two bead legs (32a?), by means of which bead legs the crest portion is connected to the sealing layer, and wherein the combustion-chamber sealing bead has screw portions, each of which lies closest to a screw hole, and has intermediate portions between the screw portions; in order to improve the sealing capability of the cylinder-head seal, the deformation resistance of the bead legs with respect to pressing forces is greater, at least in longitudinal regions of the intermediate portions, than in screw portions of the combustion-chamber sealing bead.

Abstract: The invention relates to a container precursor comprising a wall, wherein the wall a) surrounds an interior region, and b) comprises a first wall region and a second wall region. Further, the invention relates to a process for manufacturing a container precursor, a container precursor obtainable through this process, a closed container, a process for manufacturing a closed container, a closed container obtainable through this process, a use of the aforementioned container precursor, and a further use of the aforementioned container precursor.

Abstract: The present invention refers to a container precursor, comprising a sheetlike composite; wherein the sheetlike composite comprises as a layer sequence in a direction from an outer surface of the sheetlike composite to an inner surface of the sheetlike composite a) an outer polymer layer, b) a colour application, c) a carrier layer, and d) a barrier layer; wherein the sheetlike composite forms a wall of the container precursor; wherein the wall a. at least partly surrounds an interior of the container precursor, and b.

Abstract: The present invention relates to a fixation implant with an implant body which is made substantially of a ceramic material and has an external helical thread with more than one thread web and wherein a thread pitch angle of the external helical thread is in the range from 30° to 90°, and to the use thereof as an alloplastic bone implant, as an alloplastic dental implant, in production engineering, medical engineering, surgery, dental technology and/or implant technology.

Abstract: The invention relates to a container precursor comprising a wall, wherein the wall a) surrounds an interior region, and b) comprises a first wall region and a second wall region; wherein the first wall region comprises a first layer sequence comprising a first wall layer, a second wall layer and a third wall layer as overlying layers from the interior region outwards; wherein, in the first wall region, a second carrier layer is characterised by a smaller layer thickness than a first carrier layer, or a third carrier layer, or both; wherein the second wall region comprises a second layer sequence comprising first wall layer, a second wall layer and a third wall layer as overlying layers from the interior region outwards; wherein, in the second wall region, the second wall layer is connected to the third wall layer; wherein, in the second wall region, the third carrier layer is characterised by a larger layer thickness than the first carrier layer, or the third carrier layer, or both.

Abstract: A cylinder head gasket includes a metallic gasket layer having through-openings and, at its peripheral outer margin, a first sealing element for providing a seal. The first sealing element forms a sealing line extending circumferentially about the gasket layer and surrounding the through-openings. The side of the first sealing element facing away from the peripheral outer margin of the gasket layer includes a vent hole arranged adjacent to a sealing line break and located in a first gasket layer region which is, on only a first side of the gasket layer, on both sides of the sealing line break, continuously bounded by the first sealing element and a second sealing element. The first sealing element and the second sealing element extend around the first gasket layer region such that a fluid flow path extending from the sealing line break to the vent hole has at least one change in direction.

Abstract: A cylinder head gasket includes a metallic gasket layer having through-openings and, at its peripheral outer margin, a first sealing element for providing a seal. The first sealing element forms a sealing line extending circumferentially about the gasket layer and surrounding the through-openings. The side of the first sealing element facing away from the peripheral outer margin of the gasket layer includes a vent hole arranged adjacent to a sealing line break and located in a first gasket layer region which is, on only a first side of the gasket layer, on both sides of the sealing line break, continuously bounded by the first sealing element and a second sealing element. The first sealing element and the second sealing element extend around the first gasket layer region such that a fluid flow path extending from the sealing line break to the vent hole has at least one change in direction.

Abstract: Gasket, comprising at least one through-opening to be sealed, at least one elastomeric sealing element associated with the through-opening, and a carrier for the sealing element, wherein the sealing element comprises at least one flexible sealing lip enclosing the through-opening in the form of a projection protruding in the direction of the through-opening axis, and embedded in the sealing element is at least one stiff inlay, which projects in the direction of the through-opening axis beyond a carrier area adjacent to the inlay; in order that the sealing element, while in operation, will not be damaged due to high stresses or will not become detached in some areas from the carrier, the inlay surrounds the through-opening in the shape of a ring and without interruption and forms a supporting element which supports the sealing element radially around the through-opening.

Abstract: Cylinder head gasket whose gasket plate comprises a single sheet metal layer, combustion chamber openings, and for each combustion chamber opening a ring-shaped combustion chamber sealing element, which is a sheet metal ring that is arranged on the sheet metal layer and is joined to the latter by welding; to avoid the risk of damage to a combustion chamber sealing element as a result of sliding movements occurring between a cylinder head sealing surface and the cylinder head gasket while the engine is in operation, all sheet metal rings are arranged on that side of the sheet metal layer which is to face an engine block.

Abstract: Cylinder head gasket whose gasket plate comprises a single sheet metal layer, combustion chamber openings, and for each combustion chamber opening a ring-shaped combustion chamber sealing element, which is a sheet metal ring that is arranged on the sheet metal layer and is joined to the latter by welding; to avoid the risk of damage to a combustion chamber sealing element as a result of sliding movements occurring between a cylinder head sealing surface and the cylinder head gasket while the engine is in operation, all sheet metal rings are arranged on that side of the sheet metal layer which is to face an engine block.

Abstract: 1. Cylinder Head Gasket 2. In a cylinder head gasket (1) for an internal combustion piston engine, having at least one gasket layer (21, 23, 25) of metallic material which defines the main gasket plane and which has at least one combustion chamber through opening (3), on the edge of which there is a circular ring-shaped combustion chamber sealing area (15), the combustion chamber sealing area (15) is vertically profiled such that measured perpendicular to the main gasket plane it has a different thickness in different peripheral areas.