Abstract: The present invention belongs to the field of biotechnology, recombinant protein production, molecular biology, microbiology and microbial genetics. It provides a modified eukaryotic cell that is modified to the effect that the modified eukaryotic cell is not able to provide an SSN6-like related protein or an SSN6-like protein that exerts its wildtype function and/or wildtype activity, the amount of SSN6-like related protein or of SSN6-like protein being present in the modified eukaryotic cell differs from the amount of SSN6-like related protein or of SSN6-like protein being present in its wildtype form, and/or essentially no SSN6-like related protein or SSN6-like protein is present in the modified cell. Additionally, the present invention provides a polynucleotide sequence comprising a modified ssn6-like related gene or modified ssn6-like gene, and a vector comprising said polynucleoptide.

Abstract: The present invention provides a modified eukaryotic cell wherein the modified eukaryotic cell is not able to provide an SSN6-like protein that exerts its wildtype function and/or wildtype activity, the amount of SSN6-like protein being present in the modified eukaryotic cell differs from the amount of SSN6-like protein being present in its wildtype form, and/or essentially no SSN6-like protein is present in the modified cell. Additionally, the present invention provides a polynucleotide sequence comprising a modified ssn6-like gene, and a vector comprising said polynucleoptide. Additionally provided is an expression vector comprising a promoter that is repressed in the presence of SSN6-like protein, and a host cell comprising said vectors. The present invention further refers to a method for determining the purity of a composition by using the modified eukaryotic cell, to a method of expressing gene(s) of interest, and eukaryotic cells comprising modified ssn6-like gene.

Abstract: A vibration exciter, particularly for a vibration pile driver, includes at least four shafts disposed parallel to one another, on which two outer imbalance masses are disposed, in each instance, between which a central imbalance mass is positioned. The central imbalance mass is mounted on the shaft so as to rotate relative to the outer imbalance masses, in each instance. The imbalance masses of the at least four shafts are combined into two imbalance groups, the imbalance masses of which are all synchronized with one another in torsionally rigid manner, in each instance, wherein not only outer imbalance masses but also inner imbalance masses are provided in each of the two imbalance groups, and wherein a phase shifter is provided, by way of which the phasing of the two imbalance groups relative to one another can be adjusted.

Abstract: The present invention belongs to the field of biotechnology, recombinant protein production, molecular biology, microbiology and microbial genetics. It provides a modified eukaryotic cell that is modified to the effect that the modified eukaryotic cell is not able to provide an SSN6-like related protein or an SSN6-like protein that exerts its wildtype function and/or wildtype activity, the amount of SSN6-like related protein or of SSN6-like protein being present in the modified eukaryotic cell differs from the amount of SSN6-like related protein or of SSN6-like protein being present in its wildtype form, and/or essentially no SSN6-like related protein or SSN6-like protein is present in the modified cell. Additionally, the present invention provides a polynucleotide sequence comprising a modified ssn6-like related gene or modified ssn6-like gene, and a vector comprising said polynucleoptide.

Abstract: A vibration exciter, particularly for a vibration pile driver, includes at least four shafts disposed parallel to one another, on which two outer imbalance masses are disposed, in each instance, between which a central imbalance mass is positioned. The central imbalance mass is mounted on the shaft so as to rotate relative to the outer imbalance masses, in each instance. The imbalance masses of the at least four shafts are combined into two imbalance groups, the imbalance masses of which are all synchronized with one another in torsionally rigid manner, in each instance, wherein not only outer imbalance masses but also inner imbalance masses are provided in each of the two imbalance groups, and wherein a phase shifter is provided, by way of which the phasing of the two imbalance groups relative to one another can be adjusted.

Abstract: The present application, among others, relates to novel polypeptides having diterpene synthase activity, nucleic acid molecules encoding same, as well as to a gene cluster from Clitopilus passeckerianus which is thought to be involved in the biosynthetic pathway for producing pleuromutilin.

Abstract: The present invention relates to methods for producing polypeptides or nucleic acids, in particular antisense RNA and hairpin RNA in filamentous fungi. The present invention also relates to isolated Penicillium promoter sequences and to nucleic acid constructs, vectors, and host cells comprising the promoter sequences operably linked to nucleic acid sequences encoding polypeptides or nucleic acids, in particular antisense RNA and hairpin RNA. Furthermore, the present invention relates to fermentative production of small organic compounds by use of the Penicillium promoter sequences.

Abstract: Human nucleic acid sequences—mRNA, cDNA, genomic sequences—from tissue of prostate tumors, which code for gene products or parts thereof and their use, are described. In addition, the polypeptides that can be obtained by way of the sequences and their use are described.

Abstract: Human nucleic acid sequences—mRNA, cDNA, genomic sequences—from normal pancreatic tissue, which code for gene products or portions thereof, and their use, are described. In addition, the polypeptides that can be obtained by way of the sequences and their use are described.

Abstract: Human nucleic acid sequences—mRNA, cDNA, genomic sequences—from breast tumor tissue, which code for gene products or parts thereof, and their use, are described. In addition, the polypeptides that can be obtained by way of the sequences and their use are described.

Abstract: Human nucleic acid sequences—mRNA, cDNA, genomic sequences—from endometrial tumor tissue, which code for gene products or portions thereof, and their use, are described. In addition, the polypeptides that can be obtained by way of the sequences and their use are described.

Abstract: The invention relates to human nucleic acid sequences—mRNA, cDNA, genome sequences—of ovarian tumour tissue, which code for gene products or parts of these products, and to their use. The invention also relates to the polypeptides obtained by way of these sequences and to the use of same.