Patents by Inventor Thomas Spreter von Kruedenstein

Thomas Spreter von Kruedenstein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bispecific Asymmetric Heterodimers Comprising Anti-CD3 Constructs
    Publication number: 20190248897
    Abstract: Disclosed herein are isolated multi-specific heteromultimer constructs that bind to CD3 expressed on T-cells and to an antigen expressed on B-cells. The multi-specific heteromultimer constructs are capable of bridging T- and B-cells and mediating killing of B-cells. The multi-specific heteromultimer constructs are based on a heterodimeric Fc scaffold or on a segmented albumin scaffold. Also disclosed herein are multi-specific heteromultimer constructs that bind to HER2 and HER3.
    Type: Application
    Filed: January 24, 2019
    Publication date: August 15, 2019
    Inventors: Gordon Yiu Kon Ng, Surjit Bhimarao Dixit, Thomas Spreter von Kruedenstein, Nina E. Weisser