Abstract: The present invention relates to Orally Inhaled and Nasal Drug Product (OINDP) comprising a benzodiazepine, in particular remimazolam.

Abstract: An electrochemical system is described having an end plate, a stack cover plate adjacent to the end plate and at least one metallic electrical conductor. The stack cover plate has an electrically conductive contacting plate adjacent to the end plate and an electrically conductive separator plate half facing away from the end plate. The contacting plate and the separator plate half are connected to each other electrically and media-tight. The metallic electrical conductor extends to an outside of the electrochemical system. The metallic electrical conductor and the contacting plate are in one piece or the metallic electrical conductor contacts the contacting plate directly. The contacting plate and the separator plate half are bonded to each other.

Abstract: The application relates to a water transfer compound, preferably for use for the humidification of process gases for fuel cells, comprising:—a water-permeable and essentially gas-impermeable water transfer layer as well as—at least one thermoplastic protection layer which is water- and gas-permeable at least in sections, where—the water transfer layer and the thermoplastic protection layer overlap each other at least in sections and comprise a first and a second overlapping area, where—the water transfer layer in the first overlapping area is accessible for humid gases through the thermoplastic protection layer and the water transfer compound is thermocompressed in the second overlapping area so that the water transfer layer in the second overlapping area is not accessible for humid gases through the compressed thermoplastic protection layer.

Abstract: A separator plate for an electrochemical system has two metal individual plates. The plates have passage openings for operating media and possibly coolant, and distribution structures. The distribution structures are formed in the metal individual plates and which each communicate with at least two of the passage openings. A peripherally extending sealing structure is formed in each of the metal individual plates at least peripherally around the electrochemically active region and at a distance therefrom and/or peripherally around at least one of the passage openings and at a distance from the edge thereof. The cross-section of the sealing structure has a bead roof, two bead flanks, and at least in some segments, two bead feet. At least in the region of the bead roof of the sealing structure at least in some segments, the sealing structure extends sinuously with at least two wave periods having convex and concave segments.

Abstract: The present invention is directed to a pharmaceutical composition comprising a Compound (a) of a class of peptide Compounds and at least one further Compound (b) for the prevention, alleviation or/and treatment of epileptic seizures.

Abstract: An electrochemical system is described having an end plate, a stack cover plate adjacent to the end plate and at least one metallic electrical conductor. The stack cover plate has an electrically conductive contacting plate adjacent to the end plate and an electrically conductive separator plate half facing away from the end plate. The contacting plate and the separator plate half are connected to each other electrically and media-tight. The metallic electrical conductor extends to an outside of the electrochemical system. The metallic electrical conductor and the contacting plate are in one piece or the metallic electrical conductor contacts the contacting plate directly. The contacting plate and the separator plate half are bonded to each other.

Abstract: The present invention is directed to the use of a class of peptide compounds for treating diseases associated with hyperexcitability. The present invention is also directed to the use of a class of peptide compounds for treating diseases associated with dysfunction of an ion channel.

Abstract: The application relates to a water transfer compound, preferably for use for the humidification of process gases for fuel cells, comprising:—a water-permeable and essentially gas-impermeable water transfer layer as well as—at least one thermoplastic protection layer which is water- and gas-permeable at least in sections, where—the water transfer layer and the thermoplastic protection layer overlap each other at least in sections and comprise a first and a second overlapping area, where—the water transfer layer in the first overlapping area is accessible for humid gases through the thermoplastic protection layer and the water transfer compound is thermocompressed in the second overlapping area so that the water transfer layer in the second overlapping area is not accessible for humid gases through the compressed thermoplastic protection layer.

Abstract: The application relates to a water transfer compound, preferably for use for the humidification of process gases for fuel cells, comprising: —a water-permeable and essentially gas-impermeable water transfer layer as well as—at least one thermoplastic protection layer which is water- and gas-permeable at least in sections, where—the water transfer layer and the thermoplastic protection layer overlap each other at least in sections and comprise a first and a second overlapping area, where—the water transfer layer in the first overlapping area is accessible for humid gases through the thermoplastic protection layer and the water transfer compound is thermocompressed in the second overlapping area so that the water transfer layer in the second overlapping area is not accessible for humid gases through the compressed thermoplastic protection layer.

Abstract: The present invention is directed to a pharmaceutical composition comprising a Compound (a) of a class of peptide Compounds and at least one further Compound (b) for the prevention, alleviation or/and treatment of epileptic seizures.

Abstract: The present invention is directed to a pharmaceutical composition comprising a Compound (a) of a class of peptide Compounds and at least one further Compound (b) for the prevention, alleviation or/and treatment of epileptic seizures.

Abstract: A method for alleviating and/or treating epileptic seizures comprising administering a pharmaceutical composition comprising (a) lacosamide and/or a pharmaceutically acceptable salt thereof; and (b) levetiracetam and/or a pharmaceutically acceptable salt thereof is described.

Abstract: A pharmaceutical composition comprising a Compound (a) of a class of peptide Compounds and at least one further Compound (b) for the prevention, alleviation and/or treatment of epileptic seizures.

Abstract: The present invention is directed to the use of a class of peptide Compounds for prevention, alleviation or/and treatment of refractory Status epilepticus.

Abstract: The present invention is directed to the use of a class of peptide Compounds for prevention, alleviation or/and treatment of refractory Status epilepticus.

Abstract: The present invention is directed to a pharmaceutical composition comprising a Compound (a) of a class of peptide Compounds and at least one further Compound (b) for the prevention, alleviation or/and treatment of epileptic seizures.

Abstract: The present invention is directed to the use of a class of peptide compounds for treating diseases associated with hyperexcitability. The present invention is also directed to the use of a class of peptide compounds for treating diseases associated with dysfunction of an ion channel.

Abstract: The present invention is directed to the use of a class of peptide compounds for treating tumor pain, in particular bone cancer pain, for treating chemotherapy-induced pain and for treating nucleoside-induced pain.

Abstract: The present invention is directed to the use of a class of peptide compounds for treating pain in trigeminal neuralgia.

Abstract: The present invention is directed to a pharmaceutical composition comprising a Compound (a) of a class of peptide Compounds and at least one further Compound (b) for the prevention, alleviation or/and treatment of epileptic seizures.