Abstract: A computer system includes a memory configured to store instructions, and one or more processors configured to execute the instructions to cause the computer system to perform a method for event detection. The method includes obtaining a user profile and a persona category associated with the user profile corresponding to a user; receiving first data associated with the user and second data associated with one or more environmental or situational factors; detecting an event based on the first data or the second data; and querying a database in response to the detected event to determine one or more recommended actions for the user based on the user profile and the persona category of the user.

Abstract: Systems and methods are described for interpreting machine learning model predictions. An example method includes: providing a machine learning model configured to receive a plurality of features as input and provide a prediction as output, wherein the plurality of features includes an engineered feature including a combination of two or more parent features; calculating a Shapley value for each feature in the plurality of features; and allocating a respective portion of the Shapley value for the engineered feature to each of the two or more parent features.

Abstract: Provided herein are crystalline forms of a cyclin-dependent kinases (CDK) inhibitor, compositions thereof, methods of preparation thereof, and methods of use thereof.

Abstract: Systems and methods are described for interpreting machine learning model predictions. An example method includes: providing a machine learning model configured to receive a plurality of features as input and provide a prediction as output, wherein the plurality of features includes an engineered feature including a combination of two or more parent features; calculating a Shapley value for each feature in the plurality of features; and allocating a respective portion of the Shapley value for the engineered feature to each of the two or more parent features.

Abstract: A configurable alert notification communications system including an audio receiver for detecting a discrete signal transmitted by a message dispatch system, and a computer connected to the audio receiver for recording, in a first format, an audio message associated with the discrete signal. The audio message in the first format can be converted to at least one of a plurality of dissimilar formats, and it can be further converted to a new format different from the dissimilar formats as specified by an end user company. The one or more formats are sent to corresponding servers configured to accept these formats, which are in turn transmitted to a recipient on the mobile device of his choosing.