Abstract: A mounting device for mounting a sample separation unit configured for separating, preferably chromatographically separating, compounds in a fluidic sample includes a first fluid connector configured for being mechanically and fluidically coupled with a first fluid interface of the sample separation unit, a second fluid connector configured for being mechanically and fluidically coupled with a second fluid interface of the sample separation unit, and a swivel mechanism configured for swivelling the first fluid connector between a mounting orientation for mounting the first fluid interface of the sample separation unit at the first fluid connector and an alignment orientation for aligning the second fluid interface of the mounted sample separation unit with the second fluid connector for subsequently coupling the second fluid interface with the second fluid connector.

Abstract: Techniques regarding privacy preservation in a federated learning environment are provided. For example, one or more embodiments described herein can comprise a system, which can comprise a memory that can store computer executable components. The system can also comprise a processor, operably coupled to the memory, and that can execute the computer executable components stored in the memory. The computer executable components can comprise a plurality of machine learning components that can execute a machine learning algorithm to generate a plurality of model parameters. The computer executable components can also comprise an aggregator component that can synthesize a machine learning model based on an aggregate of the plurality of model parameters. The aggregator component can communicate with the plurality of machine learning components via a data privacy scheme that comprises a privacy process and a homomorphic encryption process in a federated learning environment.

Abstract: A method include obtaining a set of differentially private (DP) gradients each generated based on processing corresponding private data, and obtaining a set of public gradients each generated based on processing corresponding public data. The method also includes applying mirror descent to the set of public gradients to learn a geometry for the set of DP gradients, and reshaping the set of DP gradients based on the learned geometry. The method further includes training a machine learning model based on the reshaped set of DP gradients.

Abstract: A catheter and catheter system can use energy tailored for remodeling and/or removal of target material along a body lumen, often of atherosclerotic material of a blood vessel of a patient. An elongate flexible catheter body with a radially expandable structure may have a plurality of electrodes or other electrosurgical energy delivery surfaces to radially engage atherosclerotic material when the structure expands. An atherosclerotic material detector system may measure and/or characterize the atherosclerotic material and its location, optionally using impedance monitoring.

Abstract: A catheter and catheter system can use energy tailored for remodeling and/or removal of target material along a body lumen, often of atherosclerotic material of a blood vessel of a patient. An elongate flexible catheter body with a radially expandable structure may have a plurality of electrodes or other electrosurgical energy delivery surfaces to radially engage atherosclerotic material when the structure expands. An atherosclerotic material detector system may measure and/or characterize the atherosclerotic material and its location, optionally using impedance monitoring.

Abstract: Techniques regarding privacy preservation in a federated learning environment are provided. For example, one or more embodiments described herein can comprise a system, which can comprise a memory that can store computer executable components. The system can also comprise a processor, operably coupled to the memory, and that can execute the computer executable components stored in the memory. The computer executable components can comprise a plurality of machine learning components that can execute a machine learning algorithm to generate a plurality of model parameters. The computer executable components can also comprise an aggregator component that can synthesize a machine learning model based on an aggregate of the plurality of model parameters. The aggregator component can communicate with the plurality of machine learning components via a data privacy scheme that comprises a privacy process and a homomorphic encryption process in a federated learning environment.

Abstract: Techniques regarding privacy preservation in a federated learning environment are provided. For example, one or more embodiments described herein can comprise a system, which can comprise a memory that can store computer executable components. The system can also comprise a processor, operably coupled to the memory, and that can execute the computer executable components stored in the memory. The computer executable components can comprise a plurality of machine learning components that can execute a machine learning algorithm to generate a plurality of model parameters. The computer executable components can also comprise an aggregator component that can synthesize a machine learning model based on an aggregate of the plurality of model parameters. The aggregator component can communicate with the plurality of machine learning components via a data privacy scheme that comprises a privacy process and a homomorphic encryption process in a federated learning environment.

Abstract: A computer system may include a processor and a memory coupled thereto. The memory may include a database. The processor may be configured to randomly split the database into sub-databases and applying a database query to the sub-databases. The processor may also be configured to generate respective estimated query response values for each sub-database based upon applying the database query, calculate a median of the estimated query response values, and generate a probability distribution based upon the estimated query response values and the calculated median. The processor may further be configured to select a final estimated query response value based upon the probability distribution.

Abstract: Techniques regarding privacy preservation in a federated learning environment are provided. For example, one or more embodiments described herein can comprise a system, which can comprise a memory that can store computer executable components. The system can also comprise a processor, operably coupled to the memory, and that can execute the computer executable components stored in the memory. The computer executable components can comprise a plurality of machine learning components that can execute a machine learning algorithm to generate a plurality of model parameters. The computer executable components can also comprise an aggregator component that can synthesize a machine learning model based on an aggregate of the plurality of model parameters. The aggregator component can communicate with the plurality of machine learning components via a data privacy scheme that comprises a privacy process and a homomorphic encryption process in a federated learning environment.

Abstract: A computer system may include a processor and a memory coupled thereto. The memory may include a database. The processor may be configured to randomly split the database into sub-databases and applying a database query to the sub-databases. The processor may also be configured to generate respective estimated query response values for each sub-database based upon applying the database query, calculate a median of the estimated query response values, and generate a probability distribution based upon the estimated query response values and the calculated median. The processor may further be configured to select a final estimated query response value based upon the probability distribution.

Abstract: A catheter and catheter system for treatment of a blood vessel of a patient include an elongate flexible catheter body with a radially expandable structure. A plurality of electrodes or other electrosurgical energy delivery surfaces can radially engage material to be treated when the structure expands. A material detector near the distal end of the catheter body may measure circumferential material distribution, and a power source selectively energizes the electrodes to eccentrically treat of a body lumen.

Abstract: A catheter and catheter system for treatment of a blood vessel of a patient include an elongate flexible catheter body with a radially expandable structure. A plurality of electrodes or other electrosurgical energy delivery surfaces can radially engage material to be treated when the structure expands. A material detector near the distal end of the catheter body may measure circumferential material distribution, and a power source selectively energizes the electrodes to eccentrically treat of a body lumen.

Abstract: A catheter and catheter system can use energy tailored for remodeling and/or removal of target material along a body lumen, often of atherosclerotic material of a blood vessel of a patient. An elongate flexible catheter body with a radially expandable structure may have a plurality of electrodes or other electrosurgical energy delivery surfaces to radially engage atherosclerotic material when the structure expands. An atherosclerotic material detector system may measure and/or characterize the atherosclerotic material and its location, optionally using impedance monitoring.

Abstract: A catheter and catheter system for treatment of a blood vessel of a patient include an elongate flexible catheter body with a radially expandable structure. A plurality of electrodes or other electrosurgical energy delivery surfaces can radially engage material to be treated when the structure expands. A material detector near the distal end of the catheter body may measure circumferential material distribution, and a power source selectively energizes the electrodes to eccentrically treat of a body lumen.

Abstract: The present invention provides a lumen support stent with a clear through-lumen for use in a body lumen. The stent is formed from at least one series of sliding and locking radial elements and at least one ratcheting mechanism comprising an articulating element and a plurality of stops. The ratcheting mechanism permits one-way sliding of the radial elements from a collapsed diameter to an expanded diameter, but inhibits radial recoil from the expanded diameter.

Abstract: In preferred embodiments, this invention relates to an expandable stent, comprising a tubular member comprising at least two circumferentially-adjacent radial elements, wherein each radial element comprises an engagement slot, through which a portion of the circumferentially-adjacent radial element is slidably engaged, such that the tubular member is capable of expanding from a first collapsed diameter to a second expanded diameter, wherein the engagement slot is not a paired slot.

Abstract: The present invention provides a lumen support stent with a clear through-lumen for use in a body lumen. The stent is formed from at least one series of sliding and locking radial elements and at least one ratcheting mechanism comprising an articulating element and a plurality of stops. The ratcheting mechanism permits one-way sliding of the radial elements from a collapsed diameter to an expanded diameter, but inhibits radial recoil from the expanded diameter.

Abstract: An apparatus and method of manufacturing a wire mesh laminate includes wrapping a central core with multiple layers of mesh screen and a barrier layer having a higher melting point than the mesh screen to form a spool assembly. The spool assembly is then surrounded by an outer cover and is heated to sinter or fuse together the layers of mesh screen.

Abstract: The present invention provides a lumen support stent with a clear through-lumen for use in a body lumen. The stent is formed from at least one series of sliding and locking radial elements and at least one ratcheting mechanism comprising an articulating element and a plurality of stops. The ratcheting mechanism permits one-way sliding of the radial elements from a collapsed diameter to an expanded diameter, but inhibits radial recoil from the expanded diameter.

Abstract: The present invention provides a lumen support stent with a clear through-lumen for use in a body lumen. The stent is formed from at least one series of sliding and locking radial elements and at least one ratcheting mechanism comprising an articulating element and a plurality of stops. The ratcheting mechanism permits one-way sliding of the radial elements from a collapsed diameter to an expanded diameter, but inhibits radial recoil from the expanded diameter.