Abstract: Disclosed herein is a computer-implemented method comprising: aggregating option evaluation data for a plurality of options and for a plurality of predefined criteria; graphically displaying the user modifiable chart comprising the plurality of graphical representations of the aggregated option evaluation data, wherein: each graphical representation depicts data points visually plotted with weights, the plurality of graphical representations for the plurality of predefined criteria are visually ordered according to a rank of the plurality of predefined criteria, and the weights are based on the rank of the plurality of predefined criteria; detecting a first user input modifying the rank of at least one predefined criterion; in accordance with the first user input, automatically updating the weights of the data points; and displaying an updated user modifiable chart comprising the plurality of graphical representations of the aggregated option evaluation data.

Abstract: A pre-filled pharmaceutical package comprising a liquid formulation of a VEGF-antagonist, for example Ranibizumab, inside the package. A nonlimiting example of the package can be a syringe, cartridge, or vial, made in part or in whole of a thermoplastic polymer, coated on the interior with a tie coating or layer, a barrier coating or layer, a pH protective coating or layer, and optionally a lubricity coating or layer. Optionally, the package further comprises a bag, a blister, a pouch or any other vessel. Stability performance of the VEGF-antagonist packaged in the coated COP vessel comparable to or better than glass was obtained. The said pre-filled pharmaceutical package comprising a liquid formulation of a VEGF-antagonist is suitable for sterilization (such as for surface and/or terminal sterilization) with sterilization gas residuals being minimal and/or lower than required by ISO 10993-7.

Abstract: Systems and methods capable for use in the development of high-speed, shape-transitioning, inward-turning inlets for air-breathing hypersonic vehicles, and inlets formed thereby. The systems and methods preferably provide for designing high-speed inlets for air-breathing hypersonic vehicles, wherein unique solutions are defined in each osculating plane of the inlet. Such systems and methods optionally provide an optimization process for tuning the post throat-shock Mach number of the inlet, and/or designs a shock-capture surface using a parallel-streamlines methodology, and/or a double cowl-lip geometry to allow flow to spill overboard.

Abstract: Systems and methods capable for use in the development of high-speed, shape-transitioning, inward-turning inlets for air-breathing hypersonic vehicles, and inlets formed thereby. The systems and methods preferably provide for designing high-speed inlets for air-breathing hypersonic vehicles, wherein unique solutions are defined in each osculating plane of the inlet. Such systems and methods optionally provide an optimization process for tuning the post throat-shock Mach number of the inlet, and/or designs a shock-capture surface using a parallel-streamlines methodology, and/or a double cowl-lip geometry to allow flow to spill overboard.

Abstract: This invention relates to a pharmaceutical composition comprising or consisting essentially of the phytocannabinoids cannabidivarin (CBDV) and cannabidiol (CBD). The composition is particularly safe and efficacious for use in the treatment of neurological conditions, characterized by hyper-excitability of the central nervous system, convulsions or seizures such as occur in epilepsy. Preferably the CBDV and the CBD are present with at least one non-cannabinoid component of cannabis such as one or more terpenes or a terpene fraction. More particularly the composition further comprises one or more cannabichromene type compounds. Particularly cannabichromene propyl variant (CBCV) and/or cannabichromene (CBC).

Abstract: An electronic assembly having a power semiconductor component and a circuit carrier. The power semiconductor component has a contact region on opposite sides; the contact region facing the circuit carrier is in electrical contact with a connection region of the circuit carrier; the power semiconductor component is in electrical contact on the side facing away from the circuit carrier, in the region of the contact region, with a further circuit carrier; an additively generated connecting layer is arranged on the contact region and/or the connection region of the circuit carriers; and the connecting layer is connected to the connection region and/or the contact region using a solder connection. The connecting layer has a lower modulus of elasticity in a direction or plane extending perpendicularly to the surface of the power semiconductor component than in a direction or plane extending in parallel with the surface of the power semiconductor component.

Abstract: Apparatus and methods are disclosed for a standalone and multi-game miniature golf structure. A structure includes a digital display screen positioned to align vertically with a rear end of a putting surface and sensor(s) positioned below the digital display screen. The sensor(s) are configured to detect lateral positions at which balls cross the rear end. The structure includes processor(s), that for each shot of a plurality of miniature golf games, are configured to send command signals to the digital display screen to display putting target(s); identify, via the sensor(s), a lateral position at which a golf ball crosses the rear end of the putting surface; determine whether the lateral position of the golf ball aligns vertically with any of the putting target(s); and generate a score for the shot based on the lateral position of the golf ball relative to the putting target(s).

Abstract: A decorated laminate including: an outer ply; an inner ply; a polymer interlayer between the inner ply and the outer ply; and organic ink printed decoration on one or both of internal surfaces of the laminate between the outer ply and the polymer interlayer or between the inner ply and polymer interlayer, wherein the decorated laminate has a stone impact resistance as defined herein. Also disclosed is a method of making and using the decorated laminate.

Abstract: A magnetoresistive random access memory (MRAM) array includes a data array and a sensor array. Each MRAM cell includes a Magnetic Tunnel Junction (MTJ). Each MRAM cell of the data array stores a data bit. A first and second column of the sensor array are connected to form a sensor column which includes sensor cells, each formed by a first MRAM cell in the first column together with a second MRAM cell in the second column along a same word line. Only one of a first MTJ of the first MRAM cell or second MTJ of the second MRAM cell is used as an MTJ of the sensor cell, and drain electrodes of select transistors of the first and second MRAM cells are electrically connected. Read circuitry provides read data from the data array and a sensor output indicative of a rupture state of an MTJ of the sensor array.

Abstract: There is provided a system and method of evaluating wireless device and/or wireless network performance and/or user experience, on a wireless electronic device.

Abstract: The invention refers to a method for producing expanded polymer pellets, which comprises the following steps: melting a polymer comprising a polyamide; adding at least one blowing agent; expanding the melt through at least one die for producing an expanded polymer; and pelletizing the expanded polymer. The invention further concerns polymer pellets produced with the method as well as their use, e.g. for the production of cushioning elements for sports apparel, such as for producing soles or parts of soles of sports shoes. A further aspect of the invention concerns a method for the manufacture of molded components, comprising loading pellets of an expanded polymer material into a mold, and connecting the pellets by providing heat energy, wherein the expanded polymer material of the pellets or beads comprises a chain extender. The molded components may be used in broad ranges of application.

Abstract: This technology relates in part to methods of identifying plant cultivars based on the terpene synthase genes that are identified and/or quantified (e.g., copy number, ploidy) in the cultivars. The methods provided herein permit plant cultivars with desired characteristics/phenotypes, e.g., a desired terpene production profile, to be selected for use in various applications, such as agriculture (e.g., selecting cultivars for breeding desired characteristics and/or lineages) and medicine (e.g., therapeutic activity).

Abstract: Described are ultrasound transducer modules and handheld ultrasound imagers including thermal and acoustic management features to produce high quality ultrasound images in a portable, handheld form factor.

Abstract: Disclosed herein is a computer-implemented method comprising aggregating PFAS remediation evaluation data for a plurality of remediation options and for a plurality of predefined criteria; graphically displaying the user modifiable chart comprising the plurality of graphical representations of the aggregated PFAS remediation evaluation data, wherein: each graphical representation depicts data points visually plotted with weights, the plurality of graphical representations for the plurality of predefined criteria are visually ordered according to a rank of the plurality of predefined criteria, and the weights are based on the rank of the plurality of predefined criteria; detecting a first user input modifying the rank of at least one predefined criterion; in accordance with the first user input, automatically updating the weights of the data points; and displaying an updated user modifiable chart comprising the plurality of graphical representations of the aggregated PFAS remediation evaluation data.

Abstract: The invention relates to compounds of Formula (I) and pharmaceutically acceptable salts thereof as defined in the description; to their use in medicine; to compositions containing them; to processes for their preparation; and to intermediates used in such processes. The compounds of Formula (I) may inhibit the activity of papain-like protease (PLpro) and may be useful in the treatment of viral infections, in particular viral infections associated with PLpro activity and/or expression such as coronaviruses infections.

Abstract: A method includes depositing a coating including stoichiometric one-to-one ruthenium oxide (RuO) onto a surface of a substrate. The coating is deposited by performing an atomic layer deposition (ALD) process using at least one precursor.

Abstract: Techniques, systems, and methods are disclosed to generate messaging to view content on media devices based on predictive factors. Information may be received to trigger one or more predictive factors and then generate a candidate set of offers to view content at a media device based on the information. Based on the one or more predictive factors, confidence values may be determined for each offer in the candidate set of offers. The candidate set of offers may be ranked based on the associated confidence values. Subsequently, presentation of at least one offer of the candidate set of offers may be caused to display in a user interface screen on the media device based on the ranking.

Abstract: The present disclosure relates to systems and methods for information security, specifically for automatically detecting theft of personal data. In one implementation, a computer-implemented method for automatically detecting theft of personal data on the Internet may include at least one processor configured to execute instructions, the instructions including receiving from a user, an electronic communication containing a first search term, extracting via pattern recognition one or more patterns corresponding with the first search term, and comparing the one or more patterns with a subset of data scraped from the Internet, with the subset of data scraped from the Internet being indexed by pattern for the first search term. The instructions may also include flagging matches of the one or more patterns with the subset of data based on the comparison and transmitting information associated with the matches in a report that indicates a possible theft of personal data.

Abstract: A miniature golf hole with a spinning wheel is disclosed. An example miniature golf hole includes a spinning wheel that defines cavities arranged circumferentially about the spinning wheel. A cavity surface of each of the cavities defines one or more cavity openings through which the golf ball is capable of traveling upon entering the respective cavity. The one or more cavity openings of each of the cavities are positioned at a radial distance along the spinning wheel that is different to that of the one or more cavity openings of the other of the cavities. A transfer panel is stationary and positioned below the spinning wheel. The transfer panel includes concentric rings each of which aligns vertically with the one or more cavity openings of a respective one of the cavities to receive the golf ball from the respective cavity.

Abstract: A flush valve installation tool and associated method is used to install and uninstall chrome flush valves. The installation tool is capable of installing and uninstalling nuts of a variety of sizes without causing damage to the surfaces of the nuts. The flush valve installation tool has opposing first and second members coupled together by a pin or bolt. The first and second members each have two or more smooth jaw faces configured to engage 4 or 5 surfaces of a nut to be installed or uninstalled. The flush valve installation tool can be adjusted to select the distance between opposing jaw faces to accommodate different sized nuts.