Abstract: Provided are methods of simulating tissue healing. The methods comprise using a mechanistic computer model of the interrelated effects of inflammation, tissue damage or dysfunction and tissue healing to predict an outcome of healing of damaged tissue in vivo, thereby predicting the outcome of healing of damaged tissue in vivo. Implementations of these methods on a computing device also are provided. Non-limiting examples of diseases and/or conditions that are amenable to simulation according to the methods described herein include: a diabetes, diabetic foot ulcers, necrotizing enterocolitis, ulcerative colitis, Crohn's disease, inflammatory bowel disease, restenosis (post-angioplasty or stent implantation), incisional wounding, excisional wounding, surgery, accidental trauma, pressure ulcer, stasis ulcer, tendon rupture, vocal fold phonotrauma, otitis media and pancreatitis.

Abstract: In one aspect of the invention, a method includes determining an amount of carbon dioxide (CO2) in dialysate flowing through a dialysis system using a CO2 sensor associated with the dialysis system, determining, using a pH sensor associated with the dialysis system, a pH level of the dialysate, and calculating a level of bicarbonate in the dialysate based at least in part on the determined amount of CO2 measured in the gas and the determined pH level of the dialysate.

Abstract: A system and method are provided for a fully integrated, web-based, electronic trading platform for the primary issuance of private placement securities to pre-qualified and approved accredited investors and qualified institutional buyers. Further a transferable private securities system is provided that supports the secondary sale of securities, including equity shares in venture-backed companies. Embodiments also provide for an auto-execution method for electronic signing of documents required of buyers and sellers of privately held securities and methods for decoupling preference rights from common stock for privately held securities.

Abstract: Provided are methods of simulating tissue healing. The methods comprise using a mechanistic computer model of the interrelated effects of inflammation, tissue damage or dysfunction and tissue healing to predict an outcome of healing of damaged tissue in vivo, thereby predicting the outcome of healing of damaged tissue in vivo. Implementations of these methods on a computing device also are provided. Non-limiting examples of diseases and/or conditions that are amenable to simulation according to the methods described herein include: a diabetes, diabetic foot ulcers, necrotizing enterocolitis, ulcerative colitis, Crohn's disease, inflammatory bowel disease, restenosis (post-angioplasty or stent implantation), incisional wounding, excisional wounding, surgery, accidental trauma, pressure ulcer, stasis ulcer, tendon rupture, vocal fold phonotrauma, otitis media and pancreatitis.

Abstract: A conductivity detector detects the electrical conductivity of a fluid under analysis for determining chemical or physical properties of the fluid that are related its electrical properties. Such conductivity detectors may find use in, for example, hemodialysis systems for analyzing the effectiveness of the hemodialysis treatment. In an aspect, to improve accuracy of the conductivity measurements, the detector utilizes four-wire resistance measurement methods. In another aspect, to avoid fouling or contamination of the electrodes, the detector utilizes capacitively-coupled contactless conductivity detection (C4D) methods so that the electrodes are physically unconnected to the fluid contained in a fluid chamber. In a possible further aspect, the fluid chamber may be a disposable component removable from the electrodes. The conductivity detector can include other features such as calibration circuits and features for electrically isolating the fluid under detection from the fluid in the rest of the system.

Abstract: Polymer coated aerogel comprising aerogel substrate comprising a substantially uniform polymer coating. In an embodiment, the polymer coated aerogel is comprised of a porosity and has a compressive modulus greater than the compressive modulus of the aerogel substrate.

Abstract: The present invention relates to one of two embodiments, which provide a refrigeration jacket that can be placed over or surround electronic equipment, such as the tower of a personal computer, a plasma television, or a video game console. The primary embodiment of the invention comprises an extendable jacket or cabinet that has a plurality of cooling coils running throughout the jacket or cabinet. The invention also requires a refrigeration compressor and condenser, an electrical cord, and a closing means. When in use, the cooling coils refrigerate the surrounding air, which in turn cools the electronic item in use. The result is an electronic item that can run for pro-longed periods of time as well as higher speeds due to the removal of heat associated with the computer's processor. Other embodiments include a computer game console embodiment, a plasma television embodiment, and a non-expandable computer console embodiment.

Abstract: A preventive and/or therapeutic massage device having a fine contact edge and a pressure dispersing edge to provide alternative modes of stretching to the skin, muscles, fascia, and/or tendons of a user. The massage device includes a main body portion with first and second opposed surfaces defined between lower and upper portions and first and second ends. An upper handle portion is formed between the first and second opposed surfaces along the upper portion of the main body. The fine contact edge is formed along the lower portion of the main body and the pressure dispersing edge extends from the first opposed surface. The fine contact edge is used to provide an aggressive, deep stretch, while use of the fine contact edge in combination with the pressure dispersing edge provides a gentle stretch.

Abstract: A wall plate for premise wiring. The wall plate is preterminated with a quick-connect coupling to enable fast connection and disconnection with a complementary quick-connect coupling on a wire configured to carry an electrical signal, such as digital or analog audio, visual or related signal. The wall plate may include numerous signal interfaces for audio, visual or combination audio/visual application. By including all of the components into a modular package, installation and removal of the wall plate for premise wiring upgrades is enhanced.

Abstract: A system may include an electronic messaging management application that may access contact information. The contact information may include information maintained by one or more system users. The electronic messaging management application may determine how to process an incoming electronic message using at least a portion of the contact information. The electronic messaging management application may determine whether to send a challenge-response message to a sender of an electronic message using at least a portion of the contact information.

Abstract: Provided are methods of simulating tissue healing. The methods comprise using a mechanistic computer model of the interrelated effects of inflammation, tissue damage or dysfunction and tissue healing to predict an outcome of healing of damaged tissue in vivo, thereby predicting the outcome of healing of damaged tissue in vivo. Implementations of these methods on a computing device also are provided. Non-limiting examples of diseases and/or conditions that are amenable to simulation according to the methods described herein include: a diabetes, diabetic foot ulcers, necrotizing enterocolitis, ulcerative colitis, Crohn's disease, inflammatory bowel disease, restenosis (post-angioplasty or stent implantation), incisional wounding, excisional wounding, surgery, accidental trauma, pressure ulcer, stasis ulcer, tendon rupture, vocal fold phonotrauma, otitis media and pancreatitis.

Abstract: The present invention relates to compositions for cleaning floors. In particular, it relates to aqueous compositions for one-step cleaning and gloss enhancement of wood surfaces, especially floors. The inventive compositions comprise specific levels of a class of copolymer, chitosan, or mixtures thereof, and specific levels of surfactant. The cleaning benefits are delivered every time the compositions are used; the gloss benefits are provided over three to four cleanings and are easily strippable.

Abstract: A digital extender integrated into a wall plate assembly. The assembly includes a mounting bracket, wall plate, digital extender circuitry, electrical interface and an electrically conductive cable, wire or related cable lead. The cable lead electrically connects to a signal source and to the digital extender circuitry so that it can transmit a signal from the signal source to the electrical interface through the digital extender circuitry. By making the digital extender circuitry an integral part of the assembly, difficulties associated with packaging, transporting and connecting to the signal source are reduced.

Abstract: A method for increasing the compressive modulus of aerogels comprising: providing aerogel substrate comprising a bubble matrix in a chamber; providing monomer to the chamber, the monomer comprising vapor phase monomer which polymerizes substantially free of polymerization byproducts; depositing monomer from the vapor phase onto the surface of the aerogel substrate under deposition conditions effective to produce a vapor pressure sufficient to cause the vapor phase monomer to penetrate into the bubble matrix and deposit onto the surface of the aerogel substrate, producing a substantially uniform monomer film; and, polymerizing the substantially uniform monomer film under polymerization conditions effective to produce polymer coated aerogel comprising a substantially uniform polymer coating substantially free of polymerization byproducts.

Abstract: An air conditioning system uses microwaves to effectively destroy airborne contaminants. In one mode, air (8) is passed through a microwave-transparent tube (6) and is subjected to microwaves in the presence of one or more of water, water vapor, steam or hydrogen to cause destructive dipole polarization, electrical coupling, hydrolysis, and/or interfacial polarization of the contaminants or impurities found in the air (8). In another mode, solids or liquids are decontaminated by subjecting the objects to microwaves. Paramagnetic dust particles in the air, especially underground railway air, can also be removed using an electromagnet.

Abstract: Methods and systems are provided for coordinating a project-commitment process for an organization. An interface is provided to a computational system for coordinating communications among personnel of the organization. A request is received from a customer or an agent of the customer at the organization. The request includes specification of project parameters for a project. A series of communications within the organization are coordinated using the computational system to evaluate a capacity of the organization to implement the project in accordance with the project parameters. From the evaluated capacity, it is determined whether the organization may commit to performing the project on behalf of the customer.

Abstract: A wall plate for premise wiring. The wall plate is preterminated with a quick-connect coupling to enable fast connection and disconnection with a complementary quick-connect coupling on a wire configured to carry an electrical signal, such as digital or analog audio, visual or related signal. The wall plate may include numerous signal interfaces for audio, visual or combination audio/visual application. By including all of the components into a modular package, installation and removal of the wall plate for premise wiring upgrades is enhanced.

Abstract: Systems and methods for extracorporeal processing of blood or other body fluid for the treatment of conditions, such as sepsis, autoimmune disease, or toxemia related to kidney failure, liver failure, or drug overdose are provided. In an extracorporeal treatment system, a fraction of a body fluid is passed into a treatment fluid, at least a portion of which is then passed through a sorbent suspension reactor for treatment by a sorbent suspension. The treatment fluid circuit can be maintained at a fixed volume, which enables accurate fluid balance between the patient and the extracorporeal circuit. Some or all of the treatment fluid, optionally also containing nutrients and/or therapeutic agents, is returned to the patient. In a peritoneal dialysis system, dialysate is passed into a patient's peritoneal cavity, recovered from the cavity, passed through a sorbent suspension reactor in accordance with the invention, and returned to the cavity.

Abstract: In one embodiment, an integrated circuit chip includes a semiconductor substrate, a metal layer formed on the semiconductor substrate, and an unused auxiliary resource that is tied to ground or to a supply voltage such that current does not flow through the resource and power is not dissipated by the resource, wherein the auxiliary resource can be tied into the integrated circuit to modify operation of the chip.

Abstract: A method for increasing the compressive modulus of aerogels comprising: providing aerogel substrate comprising a bubble matrix in a chamber; providing monomer to the chamber, the monomer comprising vapor phase monomer which polymerizes substantially free of polymerization byproducts; depositing monomer from the vapor phase onto the surface of the aerogel substrate under deposition conditions effective to produce a vapor pressure sufficient to cause the vapor phase monomer to penetrate into the bubble matrix and deposit onto the surface of the aerogel substrate, producing a substantially uniform monomer film; and, polymerizing the substantially uniform monomer film under polymerization conditions effective to produce polymer coated aerogel comprising a substantially uniform polymer coating substantially free of polymerization byproducts.