Patents by Inventor Thomas Suply

Thomas Suply has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • INHIBITION OF GPR4
    Publication number: 20100144835
    Abstract: The present invention relates to the use of a GPR4 inhibitor for the manufacture of a medicament for the inhibition of angiogenesis, for instance for the inhibition of tumour growth in the treatment of cancer. In a preferred embodiment, said inhibitor is a siRNA, preferably double-stranded. In addition, the present invention further encompasses non-human animals wherein the GPR4 has been inactivated, for instance a knock-out mouse lacking GPR4, and the use of said animals as an experimental model for angiogenesis and for screening for compounds modulating angiogenesis.
    Type: Application
    Filed: December 13, 2007
    Publication date: June 10, 2010
    Inventors: Klaus Seuwen, Eric Billy, Thomas Suply, Lorenza Wyder, Janet Dawson King, Marie-Gabrielle Ludwig, Matthias Mueller, Puneeta Nath, Carol Elizabeth Jones
  • Proton-sensing g-protein coupled receptors and dna sequences thereof
    Publication number: 20070092527
    Abstract: This invention relates to the newly identified utility of certain G protein-coupled receptors (GPCRs), in particular to OGR1, GPR4 and TDAG8 (TDAG8 is also named GPR65) polypeptides, and polynucleotides encoding such GPCR polypeptides, to their use in diagnosis and to methods of identifying compounds that are agonists or antagonists to said GPCRs, and to the production of such polypeptides and polynucleotides.
    Type: Application
    Filed: June 18, 2004
    Publication date: April 26, 2007
    Applicant: NOVARTIS AG
    Inventors: Birgit Baumgarten, Carol Jones, Marie-Gabrielle Ludwig, Georg Martiny-Baron, Klaus Seuwen, Romain Wolf, Lorenza Wyder, Thomas Suply