Patents by Inventor Thomas Tibbitts

Thomas Tibbitts has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compounds and methods for inhibiting the interaction of BCL proteins with binding partners
    Publication number: 20080306127
    Abstract: One aspect of the present invention relates to heterocyclic compounds that bind to bcl proteins and inhibit Bcl function. Another aspect of the present invention relates to compositions comprising a heterocyclic compound of the invention. The present invention provides methods for treating and modulating disorders associated with hyperproliferation, such as cancer.
    Type: Application
    Filed: November 15, 2006
    Publication date: December 11, 2008
    Applicant: Infinity Pharmaceuticals, Inc.
    Inventors: Alfredo Castro, Edward Holson, Brian Hopkins, Nii Koney, Daniel Snyder, Thomas Tibbitts
  • Compounds and Methods for Inhibiting the Interaction of BCL Proteins with Binding Partners
    Publication number: 20080114167
    Abstract: The invention relates to isoxazolidine containing compounds that bind to bcl proteins and inhibit Bcl function. The compounds may be used for treating and modulating disorders associated with hyperproliferation, such as cancer.
    Type: Application
    Filed: August 21, 2007
    Publication date: May 15, 2008
    Applicant: Infinity Discovery, Inc.
    Inventors: Alfredo CASTRO, Kristopher DEPEW, Michael GROGAN, Charles JOHANNES, Edward HOLSON, Brian HOPKINS, Gregg KEANEY, Nii KONEY, Tao LIU, David MANN, Marta NEVALAINEN, Stephane PELUSO, Lawrence PEREZ, Daniel SNYDER, Thomas TIBBITTS
  • Compounds and methods for inhibiting the interaction of BCL proteins with binding partners
    Publication number: 20070161690
    Abstract: One aspect of the present invention relates to heterocyclic compounds that bind to bcl proteins and inhibit Bcl function. Another aspect of the present invention relates to compositions comprising a heterocyclic compound of the invention. The present invention provides methods for treating and modulating disorders associated with hyperproliferation, such as cancer.
    Type: Application
    Filed: November 15, 2006
    Publication date: July 12, 2007
    Applicant: Infinity Pharmaceuticals, Inc.
    Inventors: Alfredo Castro, Edward Holson, Brian Hopkins, Nii Koney, Daniel Snyder, Thomas Tibbitts
  • Pin1-Modulating compounds and methods of use thereof
    Publication number: 20060106077
    Abstract: The invention is directed to modulators, e.g., inhibitors, of Pin1 and Pin1-related proteins and the use of such modulators for treatment of Pin1 associated states, e.g., for the treatment of cancer.
    Type: Application
    Filed: July 19, 2004
    Publication date: May 18, 2006
    Applicant: PINTEX PHARMACEUTICALS, INC.
    Inventors: Robert Suto, Timothy McKee, Thomas Tibbitts, Janusz Sowadski
  • Pin1-modulating compounds and methods of use thereof
    Publication number: 20050049267
    Abstract: The invention is directed to modulators, e.g., inhibitors, of Pin1 and Pin1-related proteins and the use of such modulators for treatment of Pin1 associated states, e.g., for the treatment of cancer.
    Type: Application
    Filed: March 3, 2003
    Publication date: March 3, 2005
    Applicant: Pintex Pharmaceuticals, Inc.
    Inventors: Robert Suto, Timothy McKee, Thomas Tibbitts, Janusz Sowadski
  • Methods of treating Pin1 associated disorders by covalent modification of active site residues
    Publication number: 20050004024
    Abstract: This invention pertains to methods of treating Pin1 associated disorders through the administration of an MSPCIT. The invention further pertains to novel compounds that are able to modulate Pin1 activity by forming a specific covalent interaction with an amino acid residue in the active site of Pin1.
    Type: Application
    Filed: April 16, 2004
    Publication date: January 6, 2005
    Applicant: PINTEX PHARMACEUTICALS, INC.
    Inventor: Thomas Tibbitts
  • Pin1-modulating compounds and methods of use thereof
    Publication number: 20040214872
    Abstract: The invention is directed to modulators, e.g., inhibitors, of Pin1 and Pin1-related proteins and the use of such modulators for treatment of Pin1 associated states, e.g., for the treatment of cancer.
    Type: Application
    Filed: March 3, 2003
    Publication date: October 28, 2004
    Applicant: Pintex Pharmaceuticals, Inc.
    Inventors: Robert K. Suto, Timothy D. McKee, Thomas Tibbitts, Janusz Sowadski