Patents by Inventor Thomas Tongue

Thomas Tongue has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR NUCLEIC ACID SEQUENCING
    Publication number: 20240327909
    Abstract: Embodiments of the present application relates to methods and compositions for increasing fluorescent dye signal intensity during sequencing by synthesis. In particular, the compositions and methods described herein involve the use aqueous scan mixtures including one or more water-soluble macrocycles that can form host-guest complexes with the dyes.
    Type: Application
    Filed: March 27, 2024
    Publication date: October 3, 2024
    Inventors: Xiaolin Wu, Pietro Gatti Lafranconi, Timothy Beech, Carlo Bravin, Benedict Mackworth, Thomas Tongue, Philip Balding
  • Terahertz radiation source mounting arrangements and methods of mounting a terahertz source
    Patent number: 8796653
    Abstract: Methods and apparatus for detecting variations in electromagnetic fields, in particular, terahertz (THz) electromagnetic fields, are provided. The methods and apparatus employ polarization detection devices and controllers to maintain or vary the polarization of modulated signals as desired. The methods and apparatus are provided to characterize electromagnetic fields by directing the electromagnetic field and a probe beam upon an electro-crystal and detecting the modulation of the resulting probe beam. Detection of the modulation of the probe beam is practiced by detecting and comparing the polarization components of the modulated probe beam. Aspects of the invention may be used to analyze or detect explosives, explosive related compounds, and pharmaceuticals, among other substances. A compact apparatus, modular optical devices for use with the apparatus, sample holders, and radiation source mounts are also disclosed.
    Type: Grant
    Filed: September 20, 2010
    Date of Patent: August 5, 2014
    Assignee: Rensselaer Polytechnic Institute
    Inventors: Brian Schulkin, Xi-Cheng Zhang, Thomas Tongue, Jingzhou Xu, Jian Chen
  • Systems, methods, and devices for handling terahertz radiation
    Patent number: 7808636
    Abstract: Methods and apparatus for detecting variations in electromagnetic fields, in particular, terahertz (THz) electromagnetic fields, are provided. The methods and apparatus employ polarization detection devices and controllers to maintain or vary the polarization of modulated signals as desired. The methods and apparatus are provided to characterize electromagnetic fields by directing the electromagnetic field and a probe beam upon an electro-crystal and detecting the modulation of the resulting probe beam. Detection of the modulation of the probe beam is practiced by detecting and comparing the polarization components of the modulated probe beam. Aspects of the invention may be used to analyze or detect explosives, explosive related compounds, and pharmaceuticals, among other substances. A compact apparatus, modular optical devices for use with the apparatus, sample holders, and radiation source mounts are also disclosed.
    Type: Grant
    Filed: January 11, 2008
    Date of Patent: October 5, 2010
    Assignee: Rensselaer Polytechnic Institute
    Inventors: Brian Schulkin, Xi-Cheng Zhang, Thomas Tongue, Jingzhou Xu, Jian Chen