Abstract: A coalescing removal separator includes a separator tank having a separator input configured to receive a fluid flowing through a system having entrained gasses and solid particles, having a tank wall configured to form a volume/chamber inside the separator tank to process the fluid, and having a separator output configured to provide processed fluid that is free of at least some of the entrained gasses and solid particles; and a coalescing media arranged in the volume/chamber of the separator tank, the coalescing media having at least one helically wound brush with a stem and intertwined bristles substantially filling the volume/chamber of the separator tank and being configured to enable the at least some of the entrained gasses and solid particles to come out of the fluid.

Abstract: A coalescing removal separator includes a separator tank and a coalescing media. The separator tank has a separator input that receives a fluid flowing through an HVAC system having entrained gas and solid particles, has a tank wall that forms a volume/chamber inside the separator tank to process the fluid, and has a separator output that provides processed fluid having at least some, most or substantially all of the entrained gas and solid particles removed. The coalescing media is arranged in the volume/chamber of the separator tank, has a series of vertically aligned corrugated perforated sheets substantially filling the volume/chamber of the separator tank and removes the at least some, most or substantially all of the entrained gas and solid particles from the fluid.

Abstract: A coalescing removal separator includes a separator tank having a separator input configured to receive a fluid flowing through a system having entrained gasses and solid particles, having a tank wall configured to form a volume/chamber inside the separator tank to process the fluid, and having a separator output configured to provide processed fluid that is free of at least some of the entrained gasses and solid particles; and a coalescing media arranged in the volume/chamber of the separator tank, the coalescing media having at least one helically wound brush with a stem and intertwined bristles substantially filling the volume/chamber of the separator tank and being configured to enable the at least some of the entrained gasses and solid particles to come out of the fluid.

Abstract: The claims describe methods for isolating functionally active Factor VIII using a membrane-based separation system containing a separation membrane to create a first and second interstitial volume between at least two restriction membranes. One or more stabilizing agents are added to the sample and/or an interstitial volume. A solvent in the first interstitial volume maintains FVIII in a desired charge state. Applying a potential between the first and second interstitial volumes separates FVIII on one side of the separation membrane from unwanted molecules on the other side of the separation membrane. These methods may also be used as a substitute for one or more steps in a conventional purification scheme for the separation of native or recombinant FVIII.

Abstract: A method of removing a biological contaminant from a mixture containing a biomolecule and the biological contaminant, the method comprising: (a) placing the biomolecule and contaminant mixture in a first solvent stream, the first solvent stream being separated from a second solvent stream by an electrophoretic membrane; (b) selecting a buffer for the first solvent stream having a required pH; (c) applying an electric potential between the two solvent streams causing movement of the biomolecule through the membrane into the second solvent stream while the biological contaminant is substantially retained in the first sample stream, or if entering the membrane, being substantially prevented from entering the second solvent stream; (d) optionally, periodically stopping and reversing the electric potential to cause movement of any biological contaminants having entered the membrane to move back into the first solvent stream, wherein substantially not causing any biomolecules that have entered the second solvent st

Abstract: Methods for removing a non-enveloped virus from a sample containing a target compound and non-enveloped virus contamination place the sample containing the target compound in a solvent chamber of an electrophoresis apparatus having a cathode and an anode, and a first solvent chamber being separated from a second solvent chamber by a separation barrier that has a defined pore size. The solvent chambers and the separation barrier are located between the cathode and anode.

Abstract: A method for recovering a desired virus type from a mixture of unwanted compounds places a mixture in a first sample chamber of an electrophoresis apparatus that contains a separation membrane located between the first sample chamber and a second sample chamber. Applying an electric potential across the first and second sample chambers separates at least a portion of one virus type on one side of the separation membrane while unwanted compounds are located on the other side of the separation membrane. Either the desired virus type or the unwanted molecules move through the separation membrane. The potential is applied until the required amount of desired virus type is located on one side of the separation membrane. Approximately 50% or more of the desired virus type that is located on one side of the separation membrane remains viable or substantially unchanged after recovery.