Abstract: A magnetically steerable catheter system and method of using the system is provided. The system comprises an outer elongated, flexible member having a proximal and distal end, an inner elongated, flexible, member having a proximal end and a distal end, the inner member slidably disposed within the outer member. The system further comprises an electromagnet disposed on the distal end of one of the outer member and inner member, and a magnetically attractive element disposed on the distal end of another of the outer member and inner member. The magnetically attractive element is configured for magnetically interacting with the electromagnet to deflect the distal end of the inner member.

Abstract: Embolization, as well as related particles and methods, are described.

Abstract: Embolization, as well as related particles and methods, are described.

Abstract: A magnetically steerable catheter system and method of using the system is provided. The system comprises an outer elongated, flexible member having a proximal and distal end, an inner elongated, flexible, member having a proximal end and a distal end, the inner member slidably disposed within the outer member. The system further comprises an electromagnet disposed on the distal end of one of the outer member and inner member, and a magnetically attractive element disposed on the distal end of another of the outer member and inner member. The magnetically attractive element is configured for magnetically interacting with the electromagnet to deflect the distal end of the inner member.

Abstract: A valve may include (a) a housing defining a valve lumen adapted for fluid connection with a lumen of a catheter; (b) a substantially conical valve member coupled to the housing and extending across the valve lumen to control flow therethrough; (c) a plurality of slits extending through the valve member and separated from one another circumferentially around the valve member; and (d) a ramp formed within a distal end of the valve lumen extending proximally from a distal tip of the valve member toward a ramp vertex separated from the distal tip by a predetermined distance.

Abstract: A particle includes a ferromagnetic material, a radiopaque material, and/or an MRI-visible material.

Abstract: Embolic particles, as well as their methods of use and manufacture, are described.

Abstract: Embolic compositions and methods of delivering the compositions are disclosed. In some embodiments, an embolic composition includes a first collection of particles having a first shape, and a second collection of particles having a second shape different than the first shape.

Abstract: Syringe systems for mixing and delivery of particles into the body.

Abstract: Particles having agents are disclosed. The agents can be radioactive species. The agents can be therapeutic agents. The agents can be in and/or on the particles.

Abstract: The present invention provides a sectional crimped graft that allows graft flexibility where required and limits the overall longitudinal extension. The present invention overcomes the disadvantage of fully crimped grafts by controlling the number of crimps per unit length, crimp height, crimp geometry and their location along the graft wall, dependent on the particular end-use application. In so doing, flexibility and elongation can be controllably tailored only in areas where significant anatomical angulation is present. It may also be useful in applications other than stent grafts such as surgical grafts for aortic and peripheral areas. Limiting the overall graft longitudinal extension also facilitates the deployment of the stent-graft into the blood vessel.

Abstract: A method of treating tissue includes placing substantially spherical polymer particles in the tissue. The particles include an interior region having relatively large pores and a first region substantially surrounding the interior having fewer relatively large pores than the interior region.