Abstract: Surgical instruments include a first drive assembly having a first drive gear and a lockout mechanism positioned for releasable engagement with the first drive assembly to inhibit rotation of the first drive gear. The lockout mechanism includes a pawl and an actuator means for moving the pawl from a first position in engagement with the first drive gear to a second position spaced from the first drive gear.

Abstract: An adapter assembly includes a switch actuator, an actuation bar, and a latch. The switch actuator is movable between a proximal position, in which the switch actuator actuates a switch, and a distal position. The latch is movable between a first position, in which the latch permits proximal movement of the switch actuator, and a second position, in which the latch prevents proximal movement of the switch actuator. The latch is configured to move from the first position toward the second position in response to the actuation bar moving toward a proximal position.

Abstract: Techniques are provided for hand drawing an animation motion path for an object to follow on a graphical user interface (GUI). The motion path may be drawn with a user's finger or drawing device, such as an Apple Pencil®, by selecting a drawing tool (e.g., a freehand tool and/or straight line tool). A new motion path may be added to an existing motion path, such that the new motion path is an extension of the existing motion path. The new motion path may also be added to an end point of an existing motion path, such that the new motion path is a different segment of a motion path and is associated with a new key frame. A motion path segment may be split into additional segments with new key frames, reshaped using editing points, redrawn, and/or deleted from the overall motion path.

Abstract: Techniques are provided for hand drawing an animation motion path for an object to follow on a graphical user interface (GUI). The motion path may be drawn with a user's finger or drawing device, such as an Apple Pencil®, by selecting a drawing tool (e.g., a freehand tool and/or straight line tool). A new motion path may be added to an existing motion path, such that the new motion path is an extension of the existing motion path. The new motion path may also be added to an end point of an existing motion path, such that the new motion path is a different segment of a motion path and is associated with a new key frame. A motion path segment may be split into additional segments with new key frames, reshaped using editing points, redrawn, and/or deleted from the overall motion path.

Abstract: Techniques are provided for hand drawing an animation motion path for an object to follow on a graphical user interface (GUI). The motion path may be drawn with a user's finger or drawing device, such as an Apple Pencil®, by selecting a drawing tool (e.g., a freehand tool and/or straight line tool). A new motion path may be added to an existing motion path, such that the new motion path is an extension of the existing motion path. The new motion path may also be added to an end point of an existing motion path, such that the new motion path is a different segment of a motion path and is associated with a new key frame. A motion path segment may be split into additional segments with new key frames, reshaped using editing points, redrawn, and/or deleted from the overall motion path. In some embodiments, the actions applied to the object (e.g., motion path) may be indicated by an associated tray that provides editable context-specific properties related to the action.

Abstract: Techniques are provided for hand drawing an animation motion path for an object to follow on a graphical user interface (GUI). The motion path may be drawn with a user's finger or drawing device, such as an Apple Pencil®, by selecting a drawing tool (e.g., a freehand tool and/or straight line tool). A new motion path may be added to an existing motion path, such that the new motion path is an extension of the existing motion path. The new motion path may also be added to an end point of an existing motion path, such that the new motion path is a different segment of a motion path and is associated with a new key frame. A motion path segment may be split into additional segments with new key frames, reshaped using editing points, redrawn, and/or deleted from the overall motion path. In some embodiments, the actions applied to the object (e.g., motion path) may be indicated by an associated tray that provides editable context-specific properties related to the action.

Abstract: The present invention is drawn to a method for characterising nucleic acid molecules, which comprises the steps of: i) introducing a modified base which is a substrate for a DNA glycosylase into a DNA molecule; ii) excising the modified base with the DNA glycosylase to generate an abasic site; iii) cleaving the DNA at the abasic site to generate and release an extendible upstream DNA fragment having a 3? hydroxyl terminus; and iv) incubating the released extendible upstream DNA fragment in the presence of an enzyme allowing for extension thereof and an additional template nucleic acid and analysing resultant fragment(s).

Abstract: A method for the amplification of a template nucleic acid comprises simultaneously carrying out the steps of reacting a nucleic acid primer with said template nucleic acid, normal DNA precursor nucleotides, at least one modified DNA precursor nucleotide and a DNA polymerase so as to obtain an extended nucleic acid primer, said nucleic acid primer remaining bound to said template; cleaving the modified base-containing extended nucleic acid primer so as to generate a free 3′-OH terminus that is extendible by said DNA polymerase; and repeating steps i) and ii) on DNA fragments thereby generated. The modified precursor nucleotide may be a substrate for a DNA glycosylase or recognised by a 3′-endonuclease and determines the cleavage of the DNA and the site of the cleavage accordingly.

Abstract: A system for collecting, categorizing and searching metadata about content provided on the internet and/or intranet for delivery in accordance with customized user profiles. The system collects internet information and categorizes same for provision at a customer's intranet server. The system is additionally adapted to either passively receive or actively collect and categorize internally-provided content for delivery with the externally gathered and categorized content and for matching to user profiles.

Abstract: A novel process is presented for the detection of known mutations and polymorphisms in DNA. This process, termed glycosylase mediated polymorphism detection (GMPD) involves amplification of the target DNA using three normal dNTPs and a fourth modified dNTP, whose base is a substrate for a specific DNA-glycosylase once incorporated into the DNA.

Abstract: A radio communications apparatus employs a training routine for optimizing performance and has a modulator (64, 66) to modulate a radio channel with digital information, to provide baseband signals (I, Q) at a first data rate. A power amplifier (36) amplifies signals fed from the modulator. A feedback loop (40, 42, 44, 30) samples the output signals of the power amplifier and adjusts at least one of the amplitude and phase of the baseband signals to compensate for distortion introduced by the power amplifier. The data rate of the baseband signals is reduced during the training routine to reduce adjacent channel transmissions.

Abstract: A novel rubber band powered balloon is presented. No spine, frame, or other support member is used to resist the tension of the rubber band. Instead, the balloon, formed from a substantially non-elastomeric material, is sufficiently rigid when inflated such that supports for the rubber band can be directly connected to the balloon's outer skin. In addition, one embodiment of the present invention includes a novel flapping-vane propulsion system in which the rotational motion of the rubber band is converted into reciprocating motion of the vane.